SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v29'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 1v29 NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii) 		4 / 6 GLU B 123
GLN B  45
LYS B 117
VAL B 119
 None
 1.35A 1l2iB-1v29B:
undetectable		 1l2iB-1v29B:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 1v29 NITRILE HYDRATASE A
CHAIN
NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii) 		4 / 6 ASP A 172
ASP B 218
LEU B 196
HIS B 179
 None
 1.21A 3bj8C-1v29A:
undetectable
3bj8D-1v29A:
undetectable		 3bj8C-1v29A:
23.61
3bj8D-1v29A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 1v29 NITRILE HYDRATASE A
CHAIN
NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii) 		4 / 8 SER A 175
TYR B 176
VAL A 107
LEU A  92
 None
 1.06A 3jq7C-1v29A:
undetectable		 3jq7C-1v29A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 1v29 NITRILE HYDRATASE A
CHAIN
NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii) 		5 / 12 PHE B  13
GLY B  12
ARG A 144
GLY B   3
ARG B 163
 None
 1.36A 3jzjA-1v29B:
undetectable		 3jzjA-1v29B:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 1v29 NITRILE HYDRATASE A
CHAIN
NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii) 		3 / 3 ARG B 166
VAL A 148
THR A 121
 None
 0.73A 3ndtA-1v29B:
undetectable		 3ndtA-1v29B:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 1v29 NITRILE HYDRATASE A
CHAIN
(Bacillus
smithii) 		3 / 3 PHE A 179
SER A 174
SER A 175
 None
 0.97A 3ufgB-1v29A:
undetectable		 3ufgB-1v29A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 1v29 NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii) 		4 / 9 TYR B  72
PHE B  36
PHE B  55
ILE B  77
 None
 1.17A 4jvlA-1v29B:
undetectable		 4jvlA-1v29B:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1v29 NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii) 		4 / 6 LEU B 206
ILE B 217
THR B 150
GLY B 170
 None
 0.98A 4l39A-1v29B:
undetectable		 4l39A-1v29B:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1v29 NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii) 		4 / 7 LEU B 206
ILE B 217
THR B 150
GLY B 170
 None
 0.96A 4l39B-1v29B:
undetectable		 4l39B-1v29B:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1v29 NITRILE HYDRATASE A
CHAIN
NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii;
Bacillus
smithii) 		3 / 3 TYR B 164
SER A 145
TRP B 207
 None
 0.78A 5n8jB-1v29B:
undetectable		 5n8jB-1v29B:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1v29 NITRILE HYDRATASE A
CHAIN
NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii;
Bacillus
smithii) 		3 / 3 TYR B 164
SER A 145
TRP B 207
 None
 0.75A 5n8jA-1v29B:
undetectable		 5n8jA-1v29B:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1v29 NITRILE HYDRATASE A
CHAIN
NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii;
Bacillus
smithii) 		3 / 3 TYR B 164
SER A 145
TRP B 207
 None
 0.73A 5n8jD-1v29B:
undetectable		 5n8jD-1v29B:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1v29 NITRILE HYDRATASE A
CHAIN
(Bacillus
smithii) 		5 / 12 VAL A 177
LEU A  85
SER A 173
PRO A 127
LEU A 130
 None
 1.20A 5syfB-1v29A:
undetectable		 5syfB-1v29A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 1v29 NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii) 		4 / 6 TYR B 197
VAL B 199
ILE B 148
GLU B 146
 None
 0.79A 5z3jA-1v29B:
undetectable		 5z3jA-1v29B:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 1v29 NITRILE HYDRATASE A
CHAIN
NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii;
Bacillus
smithii) 		4 / 7 ARG B 200
ASN B 212
GLU A 167
ARG A 169
 None
 1.18A 6b8kA-1v29B:
undetectable		 6b8kA-1v29B:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 1v29 NITRILE HYDRATASE A
CHAIN
NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii;
Bacillus
smithii) 		4 / 8 ARG B 200
ASN B 212
GLU A 167
ARG A 169
 None
 1.18A 6b94A-1v29B:
undetectable		 6b94A-1v29B:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1v29 NITRILE HYDRATASE A
CHAIN
NITRILE HYDRATASE B
CHAIN
(Bacillus
smithii;
Bacillus
smithii) 		5 / 12 TYR B 164
SER A 175
ILE B 217
PHE A 179
VAL A 177
 None
 1.40A 6djzB-1v29B:
undetectable		 6djzB-1v29B:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA807_0
(GEPHYRIN)		 1v29 NITRILE HYDRATASE A
CHAIN
(Bacillus
smithii) 		4 / 4 PRO A  88
LEU A  84
VAL A 108
ARG A 106
 None
 1.42A 6fgdA-1v29A:
undetectable		 6fgdA-1v29A:
19.31