SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v2b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 1v2b 23-KDA POLYPEPTIDE
OF PHOTOSYSTEM II
OXYGEN-EVOLVING
COMPLEX
(Nicotiana
tabacum) 		5 / 12 TYR A  86
LEU A 156
GLN A  83
PHE A  74
ILE A  71
 None
 1.29A 1xosA-1v2bA:
undetectable		 1xosA-1v2bA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_A_VDNA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 1v2b 23-KDA POLYPEPTIDE
OF PHOTOSYSTEM II
OXYGEN-EVOLVING
COMPLEX
(Nicotiana
tabacum) 		5 / 12 TYR A  86
LEU A 156
GLN A  83
PHE A  74
ILE A  71
 None
 1.37A 1xotA-1v2bA:
undetectable		 1xotA-1v2bA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 1v2b 23-KDA POLYPEPTIDE
OF PHOTOSYSTEM II
OXYGEN-EVOLVING
COMPLEX
(Nicotiana
tabacum) 		5 / 12 LEU A  81
GLU A  78
LEU A 114
SER A 130
LEU A 129
 None
 1.19A 2c12C-1v2bA:
undetectable		 2c12C-1v2bA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 1v2b 23-KDA POLYPEPTIDE
OF PHOTOSYSTEM II
OXYGEN-EVOLVING
COMPLEX
(Nicotiana
tabacum) 		5 / 11 LEU A  81
GLU A  78
LEU A 114
SER A 130
LEU A 129
 None
 1.17A 2c12F-1v2bA:
undetectable		 2c12F-1v2bA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 1v2b 23-KDA POLYPEPTIDE
OF PHOTOSYSTEM II
OXYGEN-EVOLVING
COMPLEX
(Nicotiana
tabacum) 		4 / 6 LEU A  87
TYR A  86
ILE A  60
ILE A 158
 None
 0.88A 2q8hA-1v2bA:
undetectable		 2q8hA-1v2bA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 1v2b 23-KDA POLYPEPTIDE
OF PHOTOSYSTEM II
OXYGEN-EVOLVING
COMPLEX
(Nicotiana
tabacum) 		4 / 6 ASP A  85
THR A  64
PRO A  65
THR A  66
 None
 1.12A 4yoaA-1v2bA:
undetectable		 4yoaA-1v2bA:
21.74