SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 1v30 HYPOTHETICAL UPF0131
PROTEIN PH0828
(Pyrococcus
horikoshii) 		4 / 4 VAL A  86
ARG A  17
ILE A  72
THR A  88
 None
 1.26A 3cl9A-1v30A:
undetectable		 3cl9A-1v30A:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 1v30 HYPOTHETICAL UPF0131
PROTEIN PH0828
(Pyrococcus
horikoshii) 		4 / 4 VAL A  12
GLU A  60
GLY A  14
LEU A  16
 NHE  A2854 (-3.4A)
None
NHE  A2854 (-2.9A)
NHE  A2854 (-3.3A)
 1.32A 5g5gC-1v30A:
undetectable		 5g5gC-1v30A:
12.05