SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)
1v32 HYPOTHETICAL PROTEIN
RAFL09-47-K03

(Arabidopsis
thaliana)
4 / 7 TYR A  83
GLN A  94
TYR A  90
ILE A  44
None
1.22A 2ph9A-1v32A:
undetectable
2ph9B-1v32A:
undetectable
2ph9A-1v32A:
16.96
2ph9B-1v32A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)
1v32 HYPOTHETICAL PROTEIN
RAFL09-47-K03

(Arabidopsis
thaliana)
4 / 8 ILE A  77
LEU A  85
ARG A  75
GLY A  73
None
0.79A 2vdbA-1v32A:
undetectable
2vdbA-1v32A:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)
1v32 HYPOTHETICAL PROTEIN
RAFL09-47-K03

(Arabidopsis
thaliana)
4 / 8 TYR A  90
ASP A  39
VAL A  82
LEU A  20
None
1.09A 4f8hC-1v32A:
undetectable
4f8hD-1v32A:
undetectable
4f8hC-1v32A:
15.14
4f8hD-1v32A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)
1v32 HYPOTHETICAL PROTEIN
RAFL09-47-K03

(Arabidopsis
thaliana)
4 / 8 TYR A  90
ASP A  39
VAL A  82
LEU A  20
None
1.08A 4f8hD-1v32A:
undetectable
4f8hE-1v32A:
undetectable
4f8hD-1v32A:
15.14
4f8hE-1v32A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)
1v32 HYPOTHETICAL PROTEIN
RAFL09-47-K03

(Arabidopsis
thaliana)
4 / 8 VAL A  82
LEU A  20
TYR A  90
ASP A  39
None
1.08A 4f8hA-1v32A:
undetectable
4f8hE-1v32A:
undetectable
4f8hA-1v32A:
15.14
4f8hE-1v32A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
1v32 HYPOTHETICAL PROTEIN
RAFL09-47-K03

(Arabidopsis
thaliana)
5 / 12 LEU A  86
VAL A  62
LEU A  54
LEU A  68
ALA A  45
None
1.41A 4m11A-1v32A:
undetectable
4m11A-1v32A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
1v32 HYPOTHETICAL PROTEIN
RAFL09-47-K03

(Arabidopsis
thaliana)
5 / 12 ILE A  77
VAL A  62
LEU A  54
LEU A  68
ALA A  45
None
1.06A 4m11B-1v32A:
undetectable
4m11B-1v32A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)
1v32 HYPOTHETICAL PROTEIN
RAFL09-47-K03

(Arabidopsis
thaliana)
4 / 7 ILE A  77
PHE A  72
VAL A  62
ILE A  48
None
0.93A 4zzbC-1v32A:
undetectable
4zzbD-1v32A:
undetectable
4zzbC-1v32A:
14.83
4zzbD-1v32A:
14.83