SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v3y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 1v3y PEPTIDE DEFORMYLASE
(Thermus
thermophilus) 		4 / 8 ALA A  47
LEU A 108
LEU A 105
SER A 104
 None
None
OCS  A 102 ( 4.4A)
OCS  A 102 ( 3.3A)
 0.91A 1dvtA-1v3yA:
undetectable
1dvtB-1v3yA:
undetectable		 1dvtA-1v3yA:
20.81
1dvtB-1v3yA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 1v3y PEPTIDE DEFORMYLASE
(Thermus
thermophilus) 		5 / 12 MET A  33
LEU A  45
GLY A  44
VAL A 142
LEU A 150
 None
 1.39A 3h52A-1v3yA:
undetectable		 3h52A-1v3yA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 1v3y PEPTIDE DEFORMYLASE
(Thermus
thermophilus) 		3 / 3 GLU A 112
GLY A  98
THR A  99
 None
 0.49A 3iazA-1v3yA:
undetectable		 3iazA-1v3yA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1v3y PEPTIDE DEFORMYLASE
(Thermus
thermophilus) 		3 / 3 GLU A 146
HIS A 145
ARG A 141
 None
OCS  A 102 ( 3.8A)
None
 0.95A 5uunA-1v3yA:
undetectable		 5uunA-1v3yA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1v3y PEPTIDE DEFORMYLASE
(Thermus
thermophilus) 		3 / 3 ILE A 119
VAL A 121
PRO A  87
 None
 0.68A 5uunA-1v3yA:
undetectable		 5uunA-1v3yA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 1v3y PEPTIDE DEFORMYLASE
(Thermus
thermophilus) 		5 / 9 VAL A 113
GLY A  98
LEU A 105
ARG A 158
ASP A 148
 None
None
OCS  A 102 ( 4.4A)
None
None
 1.45A 6c2mC-1v3yA:
undetectable		 6c2mC-1v3yA:
17.11