SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v47'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 9 MET A 319
GLU A 172
LEU A 211
ILE A 204
LEU A 345
 None
 1.49A 1ereD-1v47A:
undetectable		 1ereD-1v47A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		4 / 8 MET A  45
LEU A 278
ARG A 273
GLY A 234
 CL  A 608 ( 4.2A)
None
None
None
 1.03A 2qd5B-1v47A:
3.4		 2qd5B-1v47A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 11 LEU A  16
THR A 228
ARG A 231
PHE A  32
MET A  33
 None
 1.50A 2vavA-1v47A:
0.9		 2vavA-1v47A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_C_CSCC1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 12 LEU A  16
THR A 228
ARG A 231
PHE A  32
MET A  33
 None
 1.48A 2vavC-1v47A:
0.8		 2vavC-1v47A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_D_CSCD1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 12 LEU A  16
THR A 228
ARG A 231
PHE A  32
MET A  33
 None
 1.46A 2vavD-1v47A:
0.8		 2vavD-1v47A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 12 LEU A  16
THR A 228
ARG A 231
PHE A  32
MET A  33
 None
 1.49A 2vavK-1v47A:
1.0		 2vavK-1v47A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_A_CSCA1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 12 LEU A  16
THR A 228
ARG A 231
PHE A  32
MET A  33
 None
 1.45A 2vaxA-1v47A:
0.9		 2vaxA-1v47A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_E_CSCE1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 12 LEU A  16
THR A 228
ARG A 231
PHE A  32
MET A  33
 None
 1.43A 2vaxE-1v47A:
1.0		 2vaxE-1v47A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_F_CSCF1384_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 12 LEU A  16
THR A 228
ARG A 231
PHE A  32
MET A  33
 None
 1.43A 2vaxF-1v47A:
0.8		 2vaxF-1v47A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 12 LEU A  16
THR A 228
ARG A 231
PHE A  32
MET A  33
 None
 1.40A 2vaxG-1v47A:
0.8		 2vaxG-1v47A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_J_CSCJ1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 12 LEU A  16
THR A 228
ARG A 231
PHE A  32
MET A  33
 None
 1.49A 2vaxJ-1v47A:
0.9		 2vaxJ-1v47A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		4 / 4 LEU A  93
PRO A 121
LEU A  95
ARG A 100
 None
 1.36A 3hcoA-1v47A:
2.8		 3hcoA-1v47A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		4 / 6 PHE A  26
HIS A  77
VAL A 130
PHE A  32
 None
 1.22A 4a97E-1v47A:
undetectable		 4a97E-1v47A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		4 / 8 GLU A 144
GLU A 145
GLY A 249
ARG A 147
 None
 1.02A 4fgzA-1v47A:
undetectable
4fgzB-1v47A:
undetectable		 4fgzA-1v47A:
19.78
4fgzB-1v47A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		4 / 9 TYR A 208
HIS A 168
PHE A 161
ILE A 190
 None
ADX  A 564 (-4.7A)
ADX  A 564 (-4.6A)
None
 1.27A 4jvlA-1v47A:
undetectable		 4jvlA-1v47A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		3 / 3 LEU A 336
LEU A 211
ASN A 165
 None
 0.59A 4otwA-1v47A:
undetectable		 4otwA-1v47A:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 11 THR A 201
GLN A 162
GLY A 192
THR A 228
ALA A 227
 None
ADX  A 564 (-3.7A)
None
None
None
 1.48A 4qvnH-1v47A:
undetectable
4qvnI-1v47A:
undetectable		 4qvnH-1v47A:
18.86
4qvnI-1v47A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 10 THR A 201
GLN A 162
GLY A 192
THR A 228
ALA A 227
 None
ADX  A 564 (-3.7A)
None
None
None
 1.48A 4qvnV-1v47A:
undetectable
4qvnW-1v47A:
undetectable		 4qvnV-1v47A:
18.86
4qvnW-1v47A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 12 ILE A 190
GLY A 192
ASP A  13
GLU A 237
VAL A 244
 None
 1.03A 5hw4A-1v47A:
undetectable		 5hw4A-1v47A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 12 ILE A 190
GLY A 192
ASP A  13
GLU A 237
VAL A 244
 None
 1.01A 5hw4C-1v47A:
undetectable		 5hw4C-1v47A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		6 / 11 LEU A  58
GLY A 126
VAL A  29
THR A  34
GLU A  36
ALA A  38
 None
 1.38A 5o96G-1v47A:
2.7		 5o96G-1v47A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 1v47 ATP SULFURYLASE
(Thermus
thermophilus) 		5 / 12 THR A  23
GLY A  24
LEU A  21
VAL A  29
ASP A  17
 None
 1.18A 6gngA-1v47A:
3.5		 6gngA-1v47A:
20.51