SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v4l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		3 / 3 TRP B 267
VAL B 242
TRP B 225
 None
 1.16A 1c4dC-1v4lB:
undetectable
1c4dD-1v4lB:
undetectable		 1c4dC-1v4lB:
8.00
1c4dD-1v4lB:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		3 / 3 VAL B 320
TRP B 225
TRP B 267
 None
 1.24A 2xdcA-1v4lB:
undetectable
2xdcB-1v4lB:
undetectable		 2xdcA-1v4lB:
8.00
2xdcB-1v4lB:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		3 / 3 TRP B 267
VAL B 320
TRP B 225
 None
 1.25A 2xdcA-1v4lB:
undetectable
2xdcB-1v4lB:
undetectable		 2xdcA-1v4lB:
8.00
2xdcB-1v4lB:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		3 / 3 VAL B 320
TRP B 225
TRP B 267
 None
 1.24A 2xdcC-1v4lB:
undetectable
2xdcD-1v4lB:
undetectable		 2xdcC-1v4lB:
8.00
2xdcD-1v4lB:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		3 / 3 TRP B 267
VAL B 320
TRP B 225
 None
 1.26A 2xdcC-1v4lB:
undetectable
2xdcD-1v4lB:
undetectable		 2xdcC-1v4lB:
8.00
2xdcD-1v4lB:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		3 / 3 TRP B 267
VAL B 320
TRP B 225
 None
 1.29A 2xdcE-1v4lB:
undetectable
2xdcF-1v4lB:
undetectable		 2xdcE-1v4lB:
8.00
2xdcF-1v4lB:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		3 / 3 VAL B 320
TRP B 225
TRP B 267
 None
 1.23A 2y5mA-1v4lB:
undetectable
2y5mB-1v4lB:
undetectable		 2y5mA-1v4lB:
8.00
2y5mB-1v4lB:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		3 / 3 TRP B 267
VAL B 320
TRP B 225
 None
 1.27A 2y5mE-1v4lB:
undetectable
2y5mF-1v4lB:
undetectable		 2y5mE-1v4lB:
8.00
2y5mF-1v4lB:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		3 / 3 VAL B 320
TRP B 225
TRP B 267
 None
 1.22A 2y6nA-1v4lB:
undetectable
2y6nB-1v4lB:
undetectable		 2y6nA-1v4lB:
8.00
2y6nB-1v4lB:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		3 / 3 TRP B 267
VAL B 320
TRP B 225
 None
 1.24A 2y6nA-1v4lB:
undetectable
2y6nB-1v4lB:
undetectable		 2y6nA-1v4lB:
8.00
2y6nB-1v4lB:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		3 / 3 TRP B 267
VAL B 320
TRP B 225
 None
 1.25A 2y6nC-1v4lB:
undetectable
2y6nD-1v4lB:
undetectable		 2y6nC-1v4lB:
8.00
2y6nD-1v4lB:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		3 / 3 TRP B 267
VAL B 320
TRP B 225
 None
 1.25A 2y6nE-1v4lB:
undetectable
2y6nF-1v4lB:
undetectable		 2y6nE-1v4lB:
8.00
2y6nF-1v4lB:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		3 / 3 VAL B 320
TRP B 225
TRP B 267
 None
 1.20A 3zq8A-1v4lB:
undetectable
3zq8B-1v4lB:
undetectable		 3zq8A-1v4lB:
8.00
3zq8B-1v4lB:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		3 / 3 TRP B 267
VAL B 242
TRP B 225
 None
 1.02A 3zq8C-1v4lB:
undetectable
3zq8D-1v4lB:
undetectable		 3zq8C-1v4lB:
8.00
3zq8D-1v4lB:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		4 / 5 VAL B 250
GLU B 249
VAL B 242
LYS B 322
 None
 1.08A 4p6vB-1v4lB:
undetectable
4p6vE-1v4lB:
undetectable		 4p6vB-1v4lB:
12.80
4p6vE-1v4lB:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		4 / 6 LEU B 309
SER B 301
PHE B 265
HIS B 263
 None
 1.14A 5om3A-1v4lB:
0.0
5om3B-1v4lB:
0.0		 5om3A-1v4lB:
19.69
5om3B-1v4lB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		4 / 4 VAL B 242
VAL B 320
TYR B 216
GLN B 217
 None
 1.35A 5qggA-1v4lB:
undetectable		 5qggA-1v4lB:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		4 / 4 VAL B 242
VAL B 320
TYR B 216
GLN B 217
 None
 1.31A 5qgoA-1v4lB:
0.0		 5qgoA-1v4lB:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		4 / 4 VAL B 242
VAL B 320
TYR B 216
GLN B 217
 None
 1.29A 5qgpA-1v4lB:
undetectable		 5qgpA-1v4lB:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		4 / 4 VAL B 242
VAL B 320
TYR B 216
GLN B 217
 None
 1.31A 5qgqA-1v4lB:
undetectable		 5qgqA-1v4lB:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1v4l MUCROCETIN BETA
CHAIN
(Protobothrops
mucrosquamatus) 		4 / 4 VAL B 242
VAL B 320
TYR B 216
GLN B 217
 None
 1.34A 5qhbA-1v4lB:
0.0		 5qhbA-1v4lB:
18.03