SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v5c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 11 THR A 421
THR A 390
LEU A 325
VAL A 328
VAL A  64
 None
 1.24A 1akdA-1v5cA:
undetectable		 1akdA-1v5cA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 8 THR A 421
LEU A 325
VAL A 328
VAL A  64
 None
 0.93A 1iwiA-1v5cA:
undetectable		 1iwiA-1v5cA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWJ_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 9 THR A 421
THR A 390
LEU A 325
VAL A 328
VAL A  64
 None
 1.10A 1iwjA-1v5cA:
0.0		 1iwjA-1v5cA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 ARG A 411
ASP A 292
ASN A 314
 None
 0.70A 1nbhA-1v5cA:
undetectable		 1nbhA-1v5cA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 ARG A 411
ASP A 292
ASN A 314
 None
 0.69A 1nbhD-1v5cA:
undetectable		 1nbhD-1v5cA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 8 THR A 421
THR A 390
LEU A 325
VAL A 328
VAL A  64
 None
 1.25A 1t86A-1v5cA:
undetectable		 1t86A-1v5cA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 9 THR A 421
THR A 390
LEU A 325
VAL A 328
VAL A  64
 None
 1.23A 1t86B-1v5cA:
0.0		 1t86B-1v5cA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 6 ILE A 215
ILE A 327
ILE A 290
ASP A 247
 None
 0.76A 1uwhA-1v5cA:
undetectable		 1uwhA-1v5cA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 6 ILE A 215
ILE A 327
ILE A 290
ASP A 247
 None
 0.76A 1uwhB-1v5cA:
undetectable		 1uwhB-1v5cA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 7 ILE A 215
ILE A 327
ILE A 290
ASP A 247
 None
 0.82A 1uwjA-1v5cA:
undetectable		 1uwjA-1v5cA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 PHE A 293
ASN A 223
ILE A 219
LEU A 163
GLY A 184
 None
 1.24A 2e7fB-1v5cA:
undetectable		 2e7fB-1v5cA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 5 SER A 321
VAL A 323
VAL A 379
SER A 246
 None
 1.20A 2j9cA-1v5cA:
undetectable
2j9cB-1v5cA:
undetectable
2j9cC-1v5cA:
undetectable		 2j9cA-1v5cA:
15.96
2j9cB-1v5cA:
15.96
2j9cC-1v5cA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 PHE A 293
ASN A 223
ILE A 219
LEU A 163
GLY A 184
 None
 1.21A 2ogyB-1v5cA:
undetectable		 2ogyB-1v5cA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 PHE A 293
ASN A 223
ILE A 219
LEU A 163
GLY A 184
 None
 1.27A 2ycjA-1v5cA:
undetectable		 2ycjA-1v5cA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 6 THR A 421
LEU A 325
VAL A 328
VAL A  64
 None
 0.82A 2z97A-1v5cA:
undetectable		 2z97A-1v5cA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_B_C2FB401_0
(AMINOMETHYLTRANSFERA
SE)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 ASP A 292
ILE A 290
TYR A 276
VAL A 323
PHE A 279
 None
 1.22A 3a8iB-1v5cA:
undetectable		 3a8iB-1v5cA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 9 THR A 421
THR A 390
LEU A 325
VAL A 328
VAL A  64
 None
 1.15A 3cppA-1v5cA:
0.0		 3cppA-1v5cA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 LEU A 420
VAL A  79
TYR A  83
PHE A  55
LEU A 133
 None
 1.18A 3medA-1v5cA:
undetectable
3medB-1v5cA:
undetectable		 3medA-1v5cA:
20.11
3medB-1v5cA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 8 THR A 154
MET A 164
LEU A  98
LEU A  95
 None
 0.92A 3nbqC-1v5cA:
undetectable		 3nbqC-1v5cA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 MET A 214
SER A 191
ILE A 188
ILE A 144
ALA A 141
 None
 1.16A 3nxuB-1v5cA:
undetectable		 3nxuB-1v5cA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 9 THR A 421
THR A 390
LEU A 325
VAL A 328
VAL A  64
 None
 1.19A 4ek1B-1v5cA:
0.0		 4ek1B-1v5cA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 4 LEU A 148
LEU A  98
GLN A 142
GLU A 210
 None
 1.25A 4i41A-1v5cA:
undetectable		 4i41A-1v5cA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 8 THR A 421
LEU A 325
VAL A 328
VAL A  64
 None
 0.91A 4l4bA-1v5cA:
0.2		 4l4bA-1v5cA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		5 / 12 ALA A 386
ILE A 389
ASN A  76
LEU A  75
GLN A  72
 None
 1.23A 4r38B-1v5cA:
undetectable		 4r38B-1v5cA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_B_377B401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 5 TYR A 375
GLU A 410
TYR A 318
PHE A 413
 None
 1.50A 4twdA-1v5cA:
2.6
4twdB-1v5cA:
2.6		 4twdA-1v5cA:
21.92
4twdB-1v5cA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 6 TYR A 334
GLU A 258
TYR A 190
PHE A 256
 None
 1.47A 4twdG-1v5cA:
0.0
4twdH-1v5cA:
0.0		 4twdG-1v5cA:
21.92
4twdH-1v5cA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 6 TYR A 375
GLU A 410
TYR A 318
PHE A 413
 None
 1.49A 4twdG-1v5cA:
0.0
4twdH-1v5cA:
0.0		 4twdG-1v5cA:
21.92
4twdH-1v5cA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 7 TYR A 276
GLY A 288
SER A 284
LEU A 367
 None
 1.12A 5bphB-1v5cA:
undetectable		 5bphB-1v5cA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 6 PHE A 424
HIS A 252
MET A 333
LEU A 420
 None
 1.06A 5dzka-1v5cA:
undetectable
5dzko-1v5cA:
undetectable		 5dzka-1v5cA:
21.26
5dzko-1v5cA:
1.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 7 PHE A 424
HIS A 252
MET A 333
LEU A 420
 None
 0.99A 5dzkD-1v5cA:
undetectable
5dzkR-1v5cA:
undetectable		 5dzkD-1v5cA:
21.26
5dzkR-1v5cA:
1.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 6 PHE A 424
HIS A 252
MET A 333
LEU A 325
 None
 1.20A 5dzke-1v5cA:
undetectable
5dzks-1v5cA:
undetectable		 5dzke-1v5cA:
21.26
5dzks-1v5cA:
1.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 6 PHE A 424
MET A 333
LEU A 420
LEU A 325
 None
 1.31A 5dzke-1v5cA:
undetectable
5dzks-1v5cA:
undetectable		 5dzke-1v5cA:
21.26
5dzks-1v5cA:
1.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 SER A 321
TYR A 317
TYR A 316
 None
 0.84A 5lakA-1v5cA:
undetectable
5lakI-1v5cA:
undetectable		 5lakA-1v5cA:
22.11
5lakI-1v5cA:
2.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 SER A 321
TYR A 317
TYR A 316
 None
 0.90A 5lakC-1v5cA:
undetectable
5lakJ-1v5cA:
undetectable		 5lakC-1v5cA:
22.11
5lakJ-1v5cA:
2.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 4 VAL A 323
LEU A 272
ASN A 319
ASP A 292
 None
 1.27A 5vcyA-1v5cA:
undetectable		 5vcyA-1v5cA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 ARG A 326
PHE A 279
LEU A 272
 None
 0.79A 5veuA-1v5cA:
undetectable		 5veuA-1v5cA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		3 / 3 GLY A 218
ASN A 160
ARG A 153
 None
 0.75A 5w7bD-1v5cA:
undetectable		 5w7bD-1v5cA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 1v5c CHITOSANASE
(Bacillus
sp.
(in:
Bacteria)) 		4 / 8 ASP A  94
TYR A 103
GLY A 125
SER A 191
 None
 1.01A 6giqL-1v5cA:
undetectable
6giqP-1v5cA:
undetectable
6giqT-1v5cA:
undetectable		 6giqL-1v5cA:
21.30
6giqP-1v5cA:
23.36
6giqT-1v5cA:
9.40