SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v5i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 1v5i IA-1=SERINE
PROTEINASE INHIBITOR
(Pleurotus
ostreatus) 		5 / 12 GLY B  43
ILE B   8
LEU B  63
GLU B  15
VAL B  13
 None
None
GOL  B2002 (-3.6A)
None
GOL  B2014 ( 4.7A)
 0.92A 3o7wA-1v5iB:
undetectable		 3o7wA-1v5iB:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 1v5i IA-1=SERINE
PROTEINASE INHIBITOR
(Pleurotus
ostreatus) 		5 / 10 LEU B  53
VAL B  25
GLY B  43
ILE B   8
LEU B  48
 None
 1.01A 3ogqA-1v5iB:
undetectable		 3ogqA-1v5iB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1v5i IA-1=SERINE
PROTEINASE INHIBITOR
(Pleurotus
ostreatus) 		3 / 3 ASP B  23
LYS B  17
LEU B  63
 None
GOL  B2014 ( 3.4A)
GOL  B2002 (-3.6A)
 1.08A 4ptjA-1v5iB:
undetectable		 4ptjA-1v5iB:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 1v5i IA-1=SERINE
PROTEINASE INHIBITOR
(Pleurotus
ostreatus) 		5 / 12 PHE B  44
ILE B  32
GLY B  29
LEU B  48
THR B  49
 None
 1.18A 5byjA-1v5iB:
undetectable		 5byjA-1v5iB:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1v5i IA-1=SERINE
PROTEINASE INHIBITOR
(Pleurotus
ostreatus) 		5 / 12 ILE B  32
GLY B  46
GLU B  15
ILE B   8
TYR B  36
 None
 1.40A 5igwA-1v5iB:
0.0		 5igwA-1v5iB:
16.91