SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v5j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 ARG A  45
GLY A  44
LEU A  80
PRO A  91
VAL A  81
 None
 1.25A 1gseA-1v5jA:
undetectable		 1gseA-1v5jA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		3 / 3 LEU A  42
LEU A  80
SER A  92
 None
 0.67A 1tlmA-1v5jA:
undetectable		 1tlmA-1v5jA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		4 / 6 LEU A  42
LEU A  80
SER A  92
THR A  94
 None
 1.27A 1tyrA-1v5jA:
3.1		 1tyrA-1v5jA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 1.03A 2f80A-1v5jA:
undetectable		 2f80A-1v5jA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 0.98A 2f80B-1v5jA:
undetectable		 2f80B-1v5jA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 1.02A 2f81A-1v5jA:
undetectable		 2f81A-1v5jA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_2
(PROTEASE)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 0.93A 2ieoB-1v5jA:
undetectable		 2ieoB-1v5jA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 0.95A 2q64A-1v5jA:
undetectable		 2q64A-1v5jA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 0.93A 2qhcB-1v5jA:
undetectable		 2qhcB-1v5jA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		4 / 7 PRO A  30
LEU A  37
ALA A  84
PHE A  87
 None
 1.05A 2vcvL-1v5jA:
undetectable		 2vcvL-1v5jA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		3 / 3 ARG A  79
GLU A  43
SER A   6
 None
 0.85A 2xctD-1v5jA:
undetectable		 2xctD-1v5jA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 0.97A 2z54A-1v5jA:
undetectable		 2z54A-1v5jA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 0.91A 3d20B-1v5jA:
undetectable		 3d20B-1v5jA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 11 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 0.91A 3ektD-1v5jA:
undetectable		 3ektD-1v5jA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 0.93A 3el5B-1v5jA:
undetectable		 3el5B-1v5jA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 0.93A 3gguA-1v5jA:
undetectable		 3gguA-1v5jA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 0.98A 3lzsA-1v5jA:
undetectable		 3lzsA-1v5jA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 0.97A 3lzsB-1v5jA:
undetectable		 3lzsB-1v5jA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 1.02A 3mwsA-1v5jA:
undetectable		 3mwsA-1v5jA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 0.89A 5t2zA-1v5jA:
undetectable		 5t2zA-1v5jA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 1v5j KIAA1355 PROTEIN
(Homo
sapiens) 		5 / 12 GLY A  85
ALA A  84
VAL A  33
GLY A  60
PRO A  11
 None
 0.88A 5t2zB-1v5jA:
undetectable		 5t2zB-1v5jA:
22.52