SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v5z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1v5z MAJOR NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Aliivibrio
fischeri) 		4 / 5 LEU A  85
VAL A  83
ALA A  79
CYH A  80
 None
 1.14A 1mz9D-1v5zA:
undetectable		 1mz9D-1v5zA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 1v5z MAJOR NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Aliivibrio
fischeri) 		5 / 11 ALA A 155
PRO A   4
LEU A  32
ALA A  35
VAL A  31
 None
 1.13A 1rv7A-1v5zA:
0.0
1rv7B-1v5zA:
undetectable		 1rv7A-1v5zA:
16.98
1rv7B-1v5zA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 1v5z MAJOR NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Aliivibrio
fischeri) 		3 / 3 SER A 121
VAL A 100
LEU A 101
 None
 0.72A 1yajG-1v5zA:
undetectable		 1yajG-1v5zA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1v5z MAJOR NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Aliivibrio
fischeri) 		5 / 8 ALA A 150
LEU A  36
LEU A  33
ILE A 191
VAL A  52
 None
 1.26A 2uxpA-1v5zA:
undetectable		 2uxpA-1v5zA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 1v5z MAJOR NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Aliivibrio
fischeri) 		4 / 8 ILE A  51
ALA A 188
ILE A  53
PHE A 176
 None
 0.84A 2w9sE-1v5zA:
undetectable		 2w9sE-1v5zA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 1v5z MAJOR NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Aliivibrio
fischeri) 		4 / 8 ASP A  98
SER A 102
GLU A 112
GLU A 113
 None
 1.08A 3sg9B-1v5zA:
1.7		 3sg9B-1v5zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1v5z MAJOR NAD(P)H-FLAVIN
OXIDOREDUCTASE
(Aliivibrio
fischeri) 		5 / 12 LEU A 189
ILE A  84
GLY A 192
SER A 161
LEU A 154
 None
 1.03A 4lmnA-1v5zA:
undetectable		 4lmnA-1v5zA:
20.00