SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v6h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E1Q_A_SALA2006_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	1v6h	DIVALENT CATION TOLERANCE PROTEIN CUTA1 (Thermus thermophilus)	4 / 6	PHE A 64 VAL A 57 LEU A 22 ALA A 63	None	1.01A	2e1qA-1v6hA: undetectable	2e1qA-1v6hA: 6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E1Q_C_SALC4006_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	1v6h	DIVALENT CATION TOLERANCE PROTEIN CUTA1 (Thermus thermophilus)	4 / 6	PHE A 64 VAL A 57 LEU A 22 ALA A 63	None	1.00A	2e1qC-1v6hA: undetectable	2e1qC-1v6hA: 6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z97_A_CAMA422_0 (CYTOCHROME P450-CAM)	1v6h	DIVALENT CATION TOLERANCE PROTEIN CUTA1 (Thermus thermophilus)	4 / 6	LEU A 74 VAL A 71 VAL A 31 VAL A 57	None	0.98A	2z97A-1v6hA: undetectable	2z97A-1v6hA: 13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B9M_A_SALA1100_1 (SERUM ALBUMIN)	1v6h	DIVALENT CATION TOLERANCE PROTEIN CUTA1 (Thermus thermophilus)	4 / 4	LEU A 55 ARG A 70 LEU A 67 ALA A 21	None	1.14A	3b9mA-1v6hA: undetectable	3b9mA-1v6hA: 10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UNI_A_SALA1344_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	1v6h	DIVALENT CATION TOLERANCE PROTEIN CUTA1 (Thermus thermophilus)	4 / 7	PHE A 64 VAL A 57 LEU A 22 ALA A 63	None	1.02A	3uniA-1v6hA: undetectable	3uniA-1v6hA: 6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G0V_A_MIXA1301_1 (DNA TOPOISOMERASE 2-BETA)	1v6h	DIVALENT CATION TOLERANCE PROTEIN CUTA1 (Thermus thermophilus)	4 / 7	ARG A 92 GLY A 90 ILE A 87 GLU A 2	None	1.12A	4g0vA-1v6hA: undetectable	4g0vA-1v6hA: 8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L4B_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	1v6h	DIVALENT CATION TOLERANCE PROTEIN CUTA1 (Thermus thermophilus)	4 / 8	LEU A 74 VAL A 71 VAL A 31 VAL A 57	None	1.03A	4l4bA-1v6hA: undetectable	4l4bA-1v6hA: 13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESG_A_1YNA701_2 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1v6h	DIVALENT CATION TOLERANCE PROTEIN CUTA1 (Thermus thermophilus)	4 / 4	LEU A 55 TYR A 41 PRO A 80 ILE A 82	None	1.13A	5esgA-1v6hA: undetectable	5esgA-1v6hA: 11.84

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2E1Q_A_SALA2006_1","XANTHINE DEHYDROGENASE\/OXIDASE","1v6h","DIVALENT CATION TOLERANCE PROTEIN CUTA1","Thermus thermophilus",4,"PHE A  64;VAL A  57;LEU A  22;ALA A  63","None","1.01A","2e1qA-1v6hA:undetectable","2e1qA-1v6hA:6.60"],["2E1Q_C_SALC4006_1","XANTHINE DEHYDROGENASE\/OXIDASE","1v6h","DIVALENT CATION TOLERANCE PROTEIN CUTA1","Thermus thermophilus",4,"PHE A  64;VAL A  57;LEU A  22;ALA A  63","None","1.00A","2e1qC-1v6hA:undetectable","2e1qC-1v6hA:6.60"],["2Z97_A_CAMA422_0","CYTOCHROME P450-CAM","1v6h","DIVALENT CATION TOLERANCE PROTEIN CUTA1","Thermus thermophilus",4,"LEU A  74;VAL A  71;VAL A  31;VAL A  57","None","0.98A","2z97A-1v6hA:undetectable","2z97A-1v6hA:13.32"],["3B9M_A_SALA1100_1","SERUM ALBUMIN","1v6h","DIVALENT CATION TOLERANCE PROTEIN CUTA1","Thermus thermophilus",4,"LEU A  55;ARG A  70;LEU A  67;ALA A  21","None","1.14A","3b9mA-1v6hA:undetectable","3b9mA-1v6hA:10.66"],["3UNI_A_SALA1344_1","XANTHINE DEHYDROGENASE\/OXIDASE","1v6h","DIVALENT CATION TOLERANCE PROTEIN CUTA1","Thermus thermophilus",4,"PHE A  64;VAL A  57;LEU A  22;ALA A  63","None","1.02A","3uniA-1v6hA:undetectable","3uniA-1v6hA:6.14"],["4G0V_A_MIXA1301_1","DNA TOPOISOMERASE 2-BETA","1v6h","DIVALENT CATION TOLERANCE PROTEIN CUTA1","Thermus thermophilus",4,"ARG A  92;GLY A  90;ILE A  87;GLU A   2","None","1.12A","4g0vA-1v6hA:undetectable","4g0vA-1v6hA:8.26"],["4L4B_A_CAMA502_0","CAMPHOR 5-MONOOXYGENASE","1v6h","DIVALENT CATION TOLERANCE PROTEIN CUTA1","Thermus thermophilus",4,"LEU A  74;VAL A  71;VAL A  31;VAL A  57","None","1.03A","4l4bA-1v6hA:undetectable","4l4bA-1v6hA:13.32"],["5ESG_A_1YNA701_2","LANOSTEROL 14-ALPHA DEMETHYLASE","1v6h","DIVALENT CATION TOLERANCE PROTEIN CUTA1","Thermus thermophilus",4,"LEU A  55;TYR A  41;PRO A  80;ILE A  82","None","1.13A","5esgA-1v6hA:undetectable","5esgA-1v6hA:11.84"]]