SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v6y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		4 / 7 GLU A 235
LEU A 236
VAL A 259
LEU A 221
 None
 1.01A 1hk3A-1v6yA:
undetectable		 1hk3A-1v6yA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		5 / 10 VAL A 296
GLY A 276
LEU A 295
TYR A 307
ILE A  33
 None
 1.41A 1sq5D-1v6yA:
0.0		 1sq5D-1v6yA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		5 / 10 PHE A 204
LEU A 227
VAL A 229
GLY A 228
VAL A 266
 None
 1.32A 2cp4A-1v6yA:
undetectable		 2cp4A-1v6yA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		3 / 3 ASN A 170
ILE A 199
MET A 188
 None
 0.82A 2h42C-1v6yA:
undetectable		 2h42C-1v6yA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_1
(DEOXYCYTIDINE KINASE)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		5 / 12 GLU A  46
VAL A  67
LEU A  25
TYR A  30
TYR A 281
 None
 1.33A 2ziaB-1v6yA:
undetectable		 2ziaB-1v6yA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		5 / 9 GLY A 292
VAL A 284
ASP A 237
ILE A 238
VAL A 210
 None
 1.48A 3fi0J-1v6yA:
undetectable		 3fi0J-1v6yA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		3 / 3 ARG A 218
THR A 234
THR A 182
 None
 0.65A 3k2hB-1v6yA:
undetectable		 3k2hB-1v6yA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_1
(YAEB-LIKE PROTEIN
RPA0152)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		4 / 5 SER A 206
ARG A 218
ASP A 216
THR A 182
 None
 1.40A 3okxA-1v6yA:
0.0		 3okxA-1v6yA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		3 / 3 TRP A 283
VAL A 274
TRP A 275
 None
 0.90A 3zq8C-1v6yA:
undetectable
3zq8D-1v6yA:
undetectable		 3zq8C-1v6yA:
4.71
3zq8D-1v6yA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		4 / 4 ASN A  39
ALA A  10
GLY A   6
THR A   4
 None
 1.34A 4bboC-1v6yA:
undetectable		 4bboC-1v6yA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		4 / 8 ASP A  65
GLY A  64
VAL A  78
HIS A 115
 None
 0.80A 4c5nC-1v6yA:
3.0		 4c5nC-1v6yA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		3 / 3 SER A 282
ASP A 279
GLN A 252
 None
 0.68A 4oltA-1v6yA:
undetectable
4oltB-1v6yA:
undetectable		 4oltA-1v6yA:
21.41
4oltB-1v6yA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		3 / 3 GLN A 252
SER A 282
ASP A 279
 None
 0.64A 4qwpA-1v6yA:
undetectable
4qwpB-1v6yA:
undetectable		 4qwpA-1v6yA:
21.41
4qwpB-1v6yA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		5 / 11 PHE A 204
ASP A 171
VAL A 189
TYR A 169
PHE A 224
 None
 1.19A 4xp4A-1v6yA:
undetectable		 4xp4A-1v6yA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XPB_A_COCA702_1
(TRANSPORTER)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		5 / 10 PHE A 204
ASP A 171
VAL A 189
TYR A 169
PHE A 224
 None
 1.22A 4xpbA-1v6yA:
undetectable		 4xpbA-1v6yA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		4 / 5 PHE A 130
SER A 131
ASN A 220
ASP A 216
 None
 1.40A 5kpcA-1v6yA:
undetectable		 5kpcA-1v6yA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 1v6y ENDO-1,4-BETA-D-XYLA
NASE AND
ENDO-1,4-BETA-XYLANA
SE B
(Cellulomonas
fimi;
Streptomyces
olivaceoviridis) 		4 / 8 ILE A 209
GLN A 252
TYR A 256
VAL A 284
 None
 1.10A 5vlmF-1v6yA:
0.0		 5vlmF-1v6yA:
19.87