SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v71'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		4 / 8 GLY A 183
GLY A 185
GLY A 186
LEU A 188
 PLP  A 350 (-3.3A)
PLP  A 350 (-3.4A)
PLP  A 350 (-3.1A)
None
 0.57A 1qzzA-1v71A:
undetectable		 1qzzA-1v71A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		4 / 8 GLY A 190
GLY A 186
GLY A 185
LEU A 187
 None
PLP  A 350 (-3.1A)
PLP  A 350 (-3.4A)
PLP  A 350 (-4.9A)
 0.65A 1qzzA-1v71A:
undetectable		 1qzzA-1v71A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 12 LYS A 166
GLY A 160
GLY A 162
ALA A 165
PHE A  23
 None
 1.14A 2dpmA-1v71A:
2.4		 2dpmA-1v71A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		3 / 3 ALA A  24
GLY A 160
SER A  66
 None
 0.60A 2ivuA-1v71A:
undetectable		 2ivuA-1v71A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		3 / 3 ALA A 234
GLY A 183
SER A 308
 None
PLP  A 350 (-3.3A)
PLP  A 350 (-2.8A)
 0.60A 2ivuA-1v71A:
undetectable		 2ivuA-1v71A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		4 / 8 LYS A 101
ILE A 124
GLU A 144
ILE A 140
 None
 0.58A 2j9dJ-1v71A:
0.0
2j9dK-1v71A:
0.0
2j9dL-1v71A:
0.0		 2j9dJ-1v71A:
16.93
2j9dK-1v71A:
16.93
2j9dL-1v71A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 12 GLY A 206
GLY A 190
GLY A 186
ASP A  12
VAL A  13
 None
None
PLP  A 350 (-3.1A)
None
None
 0.95A 2wa2A-1v71A:
undetectable		 2wa2A-1v71A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A 178
LEU A 168
VAL A  29
ILE A 307
TYR A 272
 None
 1.14A 2weyA-1v71A:
undetectable		 2weyA-1v71A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 11 THR A 239
GLY A 183
GLY A 236
PHE A  56
PRO A 151
 None
PLP  A 350 (-3.3A)
PLP  A 350 (-4.7A)
PLP  A 350 (-4.7A)
None
 0.97A 2y7kA-1v71A:
undetectable		 2y7kA-1v71A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 12 THR A 239
GLY A 183
GLY A 236
PHE A  56
PRO A 151
 None
PLP  A 350 (-3.3A)
PLP  A 350 (-4.7A)
PLP  A 350 (-4.7A)
None
 1.10A 2y7kC-1v71A:
undetectable		 2y7kC-1v71A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 12 THR A 239
GLY A 183
GLY A 236
PHE A  56
PRO A 151
 None
PLP  A 350 (-3.3A)
PLP  A 350 (-4.7A)
PLP  A 350 (-4.7A)
None
 1.10A 2y7kD-1v71A:
undetectable		 2y7kD-1v71A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 10 THR A 147
ILE A 148
HIS A  85
PRO A 150
ILE A  89
 None
 1.30A 2y7pA-1v71A:
undetectable		 2y7pA-1v71A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 10 THR A 239
GLY A 183
GLY A 236
PHE A  56
PRO A 151
 None
PLP  A 350 (-3.3A)
PLP  A 350 (-4.7A)
PLP  A 350 (-4.7A)
None
 1.02A 2y7pA-1v71A:
undetectable		 2y7pA-1v71A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 10 PHE A  39
LEU A 168
VAL A  29
VAL A 172
LEU A 175
 None
 0.97A 3gwxA-1v71A:
undetectable		 3gwxA-1v71A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		4 / 7 GLU A 208
LEU A 242
ASP A 214
THR A 239
 MG  A 360 (-3.2A)
None
MG  A 360 (-2.8A)
None
 1.00A 3mbgA-1v71A:
undetectable
3mbgB-1v71A:
undetectable		 3mbgA-1v71A:
19.56
3mbgB-1v71A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_B_SAMB6735_0
(N-LYSINE
METHYLTRANSFERASE
SETD6
TRANSCRIPTION FACTOR
P65)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 11 ALA A  55
GLY A  54
ALA A  90
TYR A 119
ASN A  84
 PLP  A 350 ( 4.4A)
None
None
None
PLP  A 350 (-3.6A)
 1.38A 3qxyB-1v71A:
0.0
3qxyQ-1v71A:
undetectable		 3qxyB-1v71A:
21.91
3qxyQ-1v71A:
5.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 12 ARG A 316
GLY A 284
ILE A 307
VAL A 280
ILE A 278
 None
PLP  A 350 ( 4.8A)
None
None
None
 1.11A 4aztA-1v71A:
2.7		 4aztA-1v71A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		3 / 3 ASN A  49
LEU A 187
PHE A  45
 None
PLP  A 350 (-4.9A)
None
 0.73A 4dajB-1v71A:
undetectable		 4dajB-1v71A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		4 / 7 ILE A 306
LEU A 178
PHE A 169
GLY A 173
 None
 0.94A 4hajA-1v71A:
undetectable		 4hajA-1v71A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 12 GLY A 190
GLY A 162
PHE A  56
GLY A 185
LEU A 242
 None
None
PLP  A 350 (-4.7A)
PLP  A 350 (-3.4A)
None
 1.07A 4n48A-1v71A:
2.2		 4n48A-1v71A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 12 GLY A 190
GLY A 162
PHE A  56
GLY A 185
LEU A 242
 None
None
PLP  A 350 (-4.7A)
PLP  A 350 (-3.4A)
None
 1.09A 4n48B-1v71A:
undetectable		 4n48B-1v71A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 12 ALA A  16
GLU A 170
VAL A  13
LEU A 178
ALA A 164
 None
 1.15A 4qrcA-1v71A:
undetectable		 4qrcA-1v71A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		4 / 7 VAL A 312
PHE A 320
HIS A 319
GLU A 315
 None
 1.19A 5ad9A-1v71A:
undetectable
5ad9B-1v71A:
undetectable		 5ad9A-1v71A:
21.33
5ad9B-1v71A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		4 / 8 SER A 189
GLY A 190
ALA A  61
GLY A 160
 None
 0.88A 5albL-1v71A:
undetectable		 5albL-1v71A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		4 / 5 SER A  82
GLY A 183
THR A 259
GLU A 208
 None
PLP  A 350 (-3.3A)
None
MG  A 360 (-3.2A)
 1.16A 5btiA-1v71A:
undetectable
5btiB-1v71A:
undetectable		 5btiA-1v71A:
20.47
5btiB-1v71A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		4 / 5 SER A  82
GLY A 183
THR A 259
GLU A 208
 None
PLP  A 350 (-3.3A)
None
MG  A 360 (-3.2A)
 1.13A 5btiC-1v71A:
undetectable
5btiD-1v71A:
undetectable		 5btiC-1v71A:
20.47
5btiD-1v71A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 12 GLY A 183
GLY A 185
GLY A 186
LEU A 187
GLU A 208
 PLP  A 350 (-3.3A)
PLP  A 350 (-3.4A)
PLP  A 350 (-3.1A)
PLP  A 350 (-4.9A)
MG  A 360 (-3.2A)
 0.90A 5c0oF-1v71A:
undetectable		 5c0oF-1v71A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		3 / 3 ASP A 228
ASN A 213
GLN A 217
 None
 0.65A 5k7uA-1v71A:
0.2		 5k7uA-1v71A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8O_B_CHDB1001_0
(GASTROTROPIN)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 12 GLN A 161
THR A 163
LEU A  91
SER A  92
SER A  66
 None
 1.45A 5l8oB-1v71A:
0.0		 5l8oB-1v71A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 12 GLY A 206
GLY A 190
GLY A 186
ASP A  12
VAL A  13
 None
None
PLP  A 350 (-3.1A)
None
None
 1.04A 5njvD-1v71A:
0.3		 5njvD-1v71A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		4 / 6 PHE A 288
LEU A 269
SER A 287
GLY A 284
 None
None
None
PLP  A 350 ( 4.8A)
 1.07A 5o4yF-1v71A:
undetectable		 5o4yF-1v71A:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 7 GLY A 160
GLY A  60
SER A 308
THR A 163
ALA A 164
 None
None
PLP  A 350 (-2.8A)
None
None
 1.34A 5o96C-1v71A:
2.9		 5o96C-1v71A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)		 1v71 HYPOTHETICAL PROTEIN
C320.14 IN
CHROMOSOME III
(Schizosaccharomy
ces
pombe) 		5 / 12 GLY A  54
GLY A 310
SER A 308
PHE A  58
THR A  27
 None
None
PLP  A 350 (-2.8A)
None
None
 1.12A 5yf0A-1v71A:
2.4		 5yf0A-1v71A:
20.49