SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v72'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 7 PHE A  12
ALA A 312
LEU A 309
VAL A 346
 None
 0.76A 1hk2A-1v72A:
undetectable		 1hk2A-1v72A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 7 ALA A 184
PHE A  52
ASN A 213
GLU A 219
 None
 1.30A 1t9wA-1v72A:
undetectable		 1t9wA-1v72A:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 5 ALA A 184
TRP A 262
LEU A 261
ALA A 266
 None
 1.15A 2jstA-1v72A:
undetectable
2jstB-1v72A:
undetectable		 2jstA-1v72A:
10.11
2jstB-1v72A:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		3 / 3 LEU A 257
LEU A 187
PHE A  52
 None
 0.47A 2pgrA-1v72A:
2.1		 2pgrA-1v72A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		5 / 8 PHE A 328
LEU A 343
VAL A 346
VAL A 288
LEU A 297
 None
 1.23A 2zujA-1v72A:
undetectable		 2zujA-1v72A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1v72 ALDOLASE
(Pseudomonas
putida) 		3 / 3 GLY A  11
GLY A 313
GLY A 315
 None
 0.34A 3bogC-1v72A:
undetectable		 3bogC-1v72A:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		3 / 3 CYH A  75
PRO A 102
ASP A 179
 None
None
PLP  A 513 (-2.8A)
 0.89A 3hlwB-1v72A:
undetectable		 3hlwB-1v72A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1v72 ALDOLASE
(Pseudomonas
putida) 		3 / 3 ALA A 294
ARG A 182
LYS A 212
 None
PLP  A 513 (-3.3A)
PLP  A 513 (-1.3A)
 0.98A 3kp3B-1v72A:
0.0		 3kp3B-1v72A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 8 GLU A  98
SER A 207
LEU A  76
ALA A 101
 None
 0.92A 3ns1L-1v72A:
undetectable		 3ns1L-1v72A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 5 ASN A  16
ASP A  97
GLU A 103
SER A  14
 None
 1.50A 3p2kC-1v72A:
undetectable		 3p2kC-1v72A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 1v72 ALDOLASE
(Pseudomonas
putida) 		5 / 12 ARG A 327
PHE A 298
ILE A 156
ALA A 150
THR A 148
 None
None
None
None
PLP  A 513 (-3.9A)
 1.16A 3s79A-1v72A:
undetectable		 3s79A-1v72A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 6 PRO A  66
SER A  77
THR A  69
THR A  67
 None
None
PLP  A 513 (-3.5A)
PLP  A 513 (-4.1A)
 1.10A 3tneA-1v72A:
undetectable		 3tneA-1v72A:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1v72 ALDOLASE
(Pseudomonas
putida) 		5 / 12 PHE A 298
CYH A 299
ILE A 306
LEU A 309
LEU A 276
 None
 1.26A 3vn2A-1v72A:
0.0		 3vn2A-1v72A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		3 / 3 ARG A 127
ARG A 131
ILE A 123
 None
 0.80A 4b7qA-1v72A:
undetectable		 4b7qA-1v72A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		3 / 3 ARG A 127
ARG A 131
ILE A 123
 None
 0.90A 4b7qC-1v72A:
undetectable		 4b7qC-1v72A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 8 ALA A 118
ASP A 160
ASP A 122
ILE A 123
 None
 0.91A 4kttB-1v72A:
undetectable		 4kttB-1v72A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1v72 ALDOLASE
(Pseudomonas
putida) 		5 / 12 GLY A 154
LEU A 187
THR A 198
GLY A 180
LEU A 206
 None
 1.01A 4n48B-1v72A:
2.5		 4n48B-1v72A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 1v72 ALDOLASE
(Pseudomonas
putida) 		3 / 3 CYH A  75
PRO A 102
ASP A 179
 None
None
PLP  A 513 (-2.8A)
 0.90A 4pm5A-1v72A:
undetectable		 4pm5A-1v72A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)		 1v72 ALDOLASE
(Pseudomonas
putida) 		5 / 9 ARG A 127
LEU A 126
LEU A 176
ILE A 147
ALA A 164
 None
 1.19A 4z69A-1v72A:
0.0		 4z69A-1v72A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_B_BEZB601_0
(BENZOATE-COENZYME A
LIGASE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		5 / 8 ALA A 220
VAL A 222
PHE A  52
ALA A 210
GLY A 209
 None
 1.45A 4zjzB-1v72A:
3.1		 4zjzB-1v72A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 5 GLU A 132
THR A 130
THR A  80
LEU A 111
 None
 1.01A 5axaA-1v72A:
undetectable		 5axaA-1v72A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 5 GLU A 132
THR A 130
THR A  80
LEU A 111
 None
 1.01A 5axaC-1v72A:
undetectable		 5axaC-1v72A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 5 GLU A 132
THR A 130
THR A  80
LEU A 111
 None
 1.01A 5hm8A-1v72A:
undetectable		 5hm8A-1v72A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 5 GLU A 132
THR A 130
THR A  80
LEU A 111
 None
 1.01A 5hm8B-1v72A:
undetectable		 5hm8B-1v72A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 5 GLU A 132
THR A 130
THR A  80
LEU A 111
 None
 1.01A 5hm8C-1v72A:
undetectable		 5hm8C-1v72A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 5 GLU A 132
THR A 130
THR A  80
LEU A 111
 None
 1.01A 5hm8D-1v72A:
undetectable		 5hm8D-1v72A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 5 GLU A 132
THR A 130
THR A  80
LEU A 111
 None
 1.01A 5hm8E-1v72A:
undetectable		 5hm8E-1v72A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 5 GLU A 132
THR A 130
THR A  80
LEU A 111
 None
 1.01A 5hm8F-1v72A:
undetectable		 5hm8F-1v72A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 5 GLU A 132
THR A 130
THR A  80
LEU A 111
 None
 1.01A 5hm8G-1v72A:
undetectable		 5hm8G-1v72A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 5 GLU A 132
THR A 130
THR A  80
LEU A 111
 None
 1.01A 5hm8H-1v72A:
undetectable		 5hm8H-1v72A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		5 / 12 ARG A 327
PHE A 298
ILE A 156
ALA A 150
THR A 148
 None
None
None
None
PLP  A 513 (-3.9A)
 1.17A 5jkvA-1v72A:
undetectable		 5jkvA-1v72A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 8 SER A 207
ASP A 179
SER A  77
SER A  92
 None
PLP  A 513 (-2.8A)
None
None
 1.00A 5l1fA-1v72A:
2.1
5l1fB-1v72A:
1.9		 5l1fA-1v72A:
17.49
5l1fB-1v72A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 4 GLU A 132
THR A 130
THR A  80
LEU A 111
 None
 0.97A 5v96A-1v72A:
2.6		 5v96A-1v72A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 4 GLU A 132
THR A 130
THR A  80
LEU A 111
 None
 0.94A 5v96B-1v72A:
undetectable		 5v96B-1v72A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 4 GLU A 132
THR A 130
THR A  80
LEU A 111
 None
 0.94A 5v96C-1v72A:
2.5		 5v96C-1v72A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 4 GLU A 132
THR A 130
THR A  80
LEU A 111
 None
 0.95A 5v96D-1v72A:
0.3		 5v96D-1v72A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1v72 ALDOLASE
(Pseudomonas
putida) 		3 / 3 LYS A 268
ASN A 265
SER A  21
 None
 1.25A 5yw0A-1v72A:
undetectable		 5yw0A-1v72A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1v72 ALDOLASE
(Pseudomonas
putida) 		4 / 7 ALA A 118
ASP A 160
ASP A 122
ILE A 123
 None
 0.84A 6fbnA-1v72A:
undetectable		 6fbnA-1v72A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_1
(-)		 1v72 ALDOLASE
(Pseudomonas
putida) 		5 / 10 GLY A 180
TYR A 256
SER A 250
PHE A  52
VAL A 203
 None
 1.42A 6gnfC-1v72A:
undetectable		 6gnfC-1v72A:
20.83