SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v76'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 1v76 RNASE P PROTEIN
PH1771P
(Pyrococcus
horikoshii) 		5 / 12 THR A 103
ALA A  99
ASP A 101
LEU A  48
ILE A  44
 None
 1.23A 1errA-1v76A:
undetectable		 1errA-1v76A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1v76 RNASE P PROTEIN
PH1771P
(Pyrococcus
horikoshii) 		4 / 7 LEU A  78
ARG A 119
ILE A  43
GLY A 109
 None
 0.95A 4eq4A-1v76A:
undetectable		 4eq4A-1v76A:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1v76 RNASE P PROTEIN
PH1771P
(Pyrococcus
horikoshii) 		4 / 7 LEU A  78
ARG A 119
ILE A  43
GLY A 109
 None
 0.93A 4eqlA-1v76A:
undetectable		 4eqlA-1v76A:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1v76 RNASE P PROTEIN
PH1771P
(Pyrococcus
horikoshii) 		4 / 7 LEU A  78
ARG A 119
ILE A  43
GLY A 109
 None
 0.96A 4eqlB-1v76A:
undetectable		 4eqlB-1v76A:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1v76 RNASE P PROTEIN
PH1771P
(Pyrococcus
horikoshii) 		4 / 6 LEU A  78
ARG A 119
ILE A  43
GLY A 109
 None
 0.94A 4l39A-1v76A:
undetectable		 4l39A-1v76A:
9.86