SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 9 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.36A 1c9sL-1v7vA:
0.3
1c9sM-1v7vA:
0.4
1c9sL-1v7vA:
6.35
1c9sM-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 9 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.37A 1c9sS-1v7vA:
0.0
1c9sT-1v7vA:
0.0
1c9sS-1v7vA:
6.35
1c9sT-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 11 GLU A 464
LEU A 470
HIS A 428
ALA A 469
GLY A 381
None
1.35A 1cmaA-1v7vA:
undetectable
1cmaB-1v7vA:
undetectable
1cmaA-1v7vA:
10.79
1cmaB-1v7vA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 11 GLU A 595
LEU A 656
GLU A 653
ALA A 597
GLY A 552
None
1.26A 1cmaA-1v7vA:
undetectable
1cmaB-1v7vA:
undetectable
1cmaA-1v7vA:
10.79
1cmaB-1v7vA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 ALA A 597
GLY A 552
GLU A 595
LEU A 656
GLU A 653
None
1.27A 1cmcA-1v7vA:
undetectable
1cmcB-1v7vA:
undetectable
1cmcA-1v7vA:
10.79
1cmcB-1v7vA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_B_SAMB105_0
(MET REPRESSOR)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLU A 595
LEU A 656
GLU A 653
ALA A 597
GLY A 552
None
1.23A 1cmcA-1v7vA:
undetectable
1cmcB-1v7vA:
undetectable
1cmcA-1v7vA:
10.79
1cmcB-1v7vA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D8C_A_SORA4000_0
(MALATE SYNTHASE G)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
3 / 3 GLN A 377
HIS A 465
PRO A 453
None
0.92A 1d8cA-1v7vA:
undetectable
1d8cA-1v7vA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.39A 1gtfP-1v7vA:
undetectable
1gtfQ-1v7vA:
undetectable
1gtfP-1v7vA:
6.35
1gtfQ-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.37A 1gtfL-1v7vA:
0.0
1gtfV-1v7vA:
0.0
1gtfL-1v7vA:
6.35
1gtfV-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 9 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.39A 1gtnR-1v7vA:
undetectable
1gtnS-1v7vA:
0.7
1gtnR-1v7vA:
6.35
1gtnS-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 GLY A 729
PHE A 448
ARG A 753
THR A 442
None
0.81A 1h4oB-1v7vA:
undetectable
1h4oB-1v7vA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 4 GLY A 770
ASP A 736
GLY A 783
THR A 775
None
0.90A 1hxbB-1v7vA:
undetectable
1hxbB-1v7vA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ALA A 597
GLY A 552
GLU A 595
LEU A 656
GLU A 653
None
1.19A 1mj2A-1v7vA:
undetectable
1mj2B-1v7vA:
undetectable
1mj2A-1v7vA:
10.79
1mj2B-1v7vA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ALA A 597
GLY A 552
GLU A 595
LEU A 656
GLU A 653
None
1.17A 1mj2C-1v7vA:
undetectable
1mj2D-1v7vA:
undetectable
1mj2C-1v7vA:
10.79
1mj2D-1v7vA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ALA A 597
GLY A 552
GLU A 595
LEU A 656
GLU A 653
None
1.19A 1mjoC-1v7vA:
undetectable
1mjoD-1v7vA:
undetectable
1mjoC-1v7vA:
10.79
1mjoD-1v7vA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 11 GLU A 595
LEU A 656
GLU A 653
ALA A 597
GLY A 552
None
1.23A 1mjqA-1v7vA:
undetectable
1mjqB-1v7vA:
undetectable
1mjqA-1v7vA:
10.79
1mjqB-1v7vA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLU A 595
LEU A 656
GLU A 653
ALA A 597
GLY A 552
None
1.22A 1mjqC-1v7vA:
undetectable
1mjqD-1v7vA:
undetectable
1mjqC-1v7vA:
10.79
1mjqD-1v7vA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ALA A 597
GLY A 552
GLU A 595
LEU A 656
GLU A 653
None
1.14A 1mjqC-1v7vA:
undetectable
1mjqD-1v7vA:
undetectable
1mjqC-1v7vA:
10.79
1mjqD-1v7vA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 11 GLU A 595
LEU A 656
GLU A 653
ALA A 597
GLY A 552
None
1.22A 1mjqI-1v7vA:
undetectable
1mjqJ-1v7vA:
undetectable
1mjqI-1v7vA:
10.79
1mjqJ-1v7vA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ALA A 597
GLY A 552
GLU A 595
LEU A 656
GLU A 653
None
1.13A 1mjqI-1v7vA:
undetectable
1mjqJ-1v7vA:
undetectable
1mjqI-1v7vA:
10.79
1mjqJ-1v7vA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
3 / 3 ASP A 426
HIS A 385
ASP A 350
None
0.86A 1nw5A-1v7vA:
undetectable
1nw5A-1v7vA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 7 THR A 530
TYR A 531
ASN A 537
LEU A 512
None
1.12A 1qzrA-1v7vA:
undetectable
1qzrA-1v7vA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.36A 1utdN-1v7vA:
undetectable
1utdO-1v7vA:
undetectable
1utdN-1v7vA:
6.35
1utdO-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.40A 1utdR-1v7vA:
0.0
1utdS-1v7vA:
0.0
1utdR-1v7vA:
6.35
1utdS-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 ASP A 388
GLY A 376
ASP A 427
THR A 423
None
0.93A 2aouA-1v7vA:
undetectable
2aouA-1v7vA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 LEU A 227
ALA A 228
GLN A 231
CYH A 245
PHE A 152
None
1.08A 2oaxB-1v7vA:
undetectable
2oaxB-1v7vA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 LEU A 227
ALA A 228
GLN A 231
CYH A 245
PHE A 152
None
1.02A 2oaxE-1v7vA:
undetectable
2oaxE-1v7vA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 LEU A 227
ALA A 228
GLN A 231
CYH A 245
PHE A 152
None
1.06A 2oaxF-1v7vA:
undetectable
2oaxF-1v7vA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 HIS A 385
SER A 425
SER A 501
ASP A 492
None
1.21A 2obvA-1v7vA:
undetectable
2obvA-1v7vA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 HIS A 385
SER A 425
SER A 501
ASP A 492
None
1.16A 2p02A-1v7vA:
undetectable
2p02A-1v7vA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
3 / 3 ARG A 681
THR A 709
VAL A 689
None
0.99A 2q64A-1v7vA:
undetectable
2q64A-1v7vA:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
6 / 12 ALA A 455
TYR A 454
GLY A 383
GLY A 376
ASP A 422
GLY A 381
None
1.09A 2qe6A-1v7vA:
undetectable
2qe6A-1v7vA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
3 / 3 THR A  56
SER A  45
PHE A 337
None
0.79A 3d4sA-1v7vA:
undetectable
3d4sA-1v7vA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 4 GLY A 770
ASP A 736
GLY A 783
THR A 775
None
0.88A 3k4vC-1v7vA:
undetectable
3k4vC-1v7vA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 11 GLN A 674
ASN A 670
VAL A 719
ALA A 718
THR A 321
None
1.20A 3n23A-1v7vA:
undetectable
3n23A-1v7vA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 11 GLN A 674
ASN A 670
VAL A 719
ALA A 718
THR A 321
None
1.21A 3n23C-1v7vA:
undetectable
3n23C-1v7vA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 11 GLU A 184
TYR A 198
GLY A 273
ILE A 265
ALA A 130
None
0.79A 3nmuB-1v7vA:
2.1
3nmuJ-1v7vA:
undetectable
3nmuB-1v7vA:
19.11
3nmuJ-1v7vA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_B_ACTB601_0
(CHOLINE OXIDASE)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 5 TRP A  86
ILE A 100
HIS A  39
VAL A  20
None
1.47A 3nneB-1v7vA:
0.9
3nneB-1v7vA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_D_ACTD601_0
(CHOLINE OXIDASE)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 5 TRP A  86
ILE A 100
HIS A  39
VAL A  20
None
1.47A 3nneD-1v7vA:
0.0
3nneD-1v7vA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 PHE A 448
MET A 440
PHE A 730
ALA A 511
ALA A 468
None
0.90A 3nxuB-1v7vA:
undetectable
3nxuB-1v7vA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ASP A 549
GLY A 573
GLY A 557
PHE A 618
THR A 567
None
1.06A 3prsA-1v7vA:
undetectable
3prsA-1v7vA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_A_SAMA6734_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ALA A 469
GLY A 381
TYR A 382
ALA A 352
LEU A 512
None
1.12A 3qxyA-1v7vA:
undetectable
3qxyA-1v7vA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 11 ALA A 469
GLY A 381
TYR A 382
ALA A 352
LEU A 512
None
1.15A 3rc0A-1v7vA:
undetectable
3rc0A-1v7vA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_B_SAMB480_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
6 / 12 ALA A 469
GLY A 381
TYR A 382
ALA A 352
TYR A 348
LEU A 512
None
1.49A 3rc0B-1v7vA:
undetectable
3rc0B-1v7vA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
3 / 3 ARG A 753
GLU A 444
THR A 445
None
0.91A 3v4tA-1v7vA:
undetectable
3v4tA-1v7vA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 SER A 235
ASN A 236
GLY A 232
GLN A 231
None
0.94A 4af0A-1v7vA:
undetectable
4af0A-1v7vA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ASP A 667
TYR A 666
TRP A 650
THR A 321
ALA A 718
None
1.19A 4dajA-1v7vA:
0.0
4dajA-1v7vA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ASP A 667
TYR A 666
TRP A 650
THR A 321
ALA A 718
None
1.30A 4dajB-1v7vA:
0.1
4dajB-1v7vA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 PHE A 717
GLY A 713
SER A 712
ASP A 350
ALA A 355
None
1.16A 4dx5B-1v7vA:
undetectable
4dx5B-1v7vA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_2
(SUGAR KINASE PROTEIN)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 4 SER A  49
TYR A  52
GLY A 345
PRO A 389
None
1.34A 4e3aA-1v7vA:
undetectable
4e3aA-1v7vA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 GLY A 273
GLY A 271
LYS A 270
ASP A 210
GLY A 211
None
1.00A 4fp9D-1v7vA:
undetectable
4fp9D-1v7vA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 PRO A 740
GLY A 745
ASN A 763
SER A 308
LEU A 313
None
1.36A 4kowA-1v7vA:
1.1
4kowA-1v7vA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 HIS A 385
SER A 425
SER A 501
ASP A 492
None
1.20A 4kttC-1v7vA:
undetectable
4kttC-1v7vA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 HIS A 385
SER A 425
SER A 501
ASP A 492
None
1.18A 4ndnA-1v7vA:
undetectable
4ndnA-1v7vA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 11 MET A 466
PHE A 447
ILE A 452
ARG A 367
ILE A 370
None
1.49A 4p68A-1v7vA:
undetectable
4p68A-1v7vA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ALA A 228
GLY A 218
ALA A 238
GLY A 211
TYR A 209
None
1.09A 4r29A-1v7vA:
0.0
4r29A-1v7vA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ALA A 228
GLY A 218
ALA A 238
GLY A 211
TYR A 209
None
1.05A 4r29B-1v7vA:
undetectable
4r29B-1v7vA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ALA A 228
GLY A 218
ALA A 238
GLY A 211
TYR A 209
None
0.98A 4r29C-1v7vA:
undetectable
4r29C-1v7vA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ALA A 228
GLY A 218
ALA A 238
GLY A 211
TYR A 209
None
1.06A 4r29D-1v7vA:
undetectable
4r29D-1v7vA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 THR A 581
LEU A 605
LEU A 669
ILE A 641
None
0.81A 4r38A-1v7vA:
undetectable
4r38A-1v7vA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 THR A 581
LEU A 605
LEU A 669
ILE A 641
None
0.80A 4r38D-1v7vA:
undetectable
4r38D-1v7vA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZU_B_Y70B505_1
(PROTEIN CEREBLON)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 7 TRP A 320
PHE A   6
THR A 327
TRP A 707
None
1.27A 4tzuB-1v7vA:
0.0
4tzuC-1v7vA:
undetectable
4tzuB-1v7vA:
9.09
4tzuC-1v7vA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ASP A 667
TYR A 666
TRP A 650
THR A 321
ALA A 718
None
1.35A 4u14A-1v7vA:
undetectable
4u14A-1v7vA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 PHE A 717
GLY A 713
SER A 712
ASP A 350
ALA A 355
None
1.13A 4u8vB-1v7vA:
2.7
4u8vB-1v7vA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_1
(MINERALOCORTICOID
RECEPTOR)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ALA A 228
GLN A 231
SER A 235
CYH A 245
PHE A 152
None
1.34A 4udaA-1v7vA:
undetectable
4udaA-1v7vA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 6 LEU A 669
ASN A 670
PRO A 671
ARG A 333
None
1.22A 4yv5B-1v7vA:
undetectable
4yv5B-1v7vA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 6 LEU A 669
ASN A 670
PRO A 671
ARG A 333
None
1.26A 4yv5A-1v7vA:
undetectable
4yv5A-1v7vA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 HIS A 385
SER A 425
SER A 501
ASP A 492
None
1.14A 5a1iA-1v7vA:
undetectable
5a1iA-1v7vA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 5 PHE A 150
ASP A 210
PHE A 216
VAL A 229
None
1.20A 5a1rA-1v7vA:
undetectable
5a1rA-1v7vA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 5 SER A 728
ARG A 300
GLU A 326
ARG A 750
None
1.16A 5cdqR-1v7vA:
undetectable
5cdqS-1v7vA:
undetectable
5cdqT-1v7vA:
undetectable
5cdqR-1v7vA:
19.85
5cdqS-1v7vA:
14.14
5cdqT-1v7vA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.43A 5eeuN-1v7vA:
0.3
5eeuO-1v7vA:
0.3
5eeuN-1v7vA:
6.35
5eeuO-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.44A 5eeuP-1v7vA:
0.3
5eeuQ-1v7vA:
undetectable
5eeuP-1v7vA:
6.35
5eeuQ-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.40A 5eeuS-1v7vA:
0.0
5eeuT-1v7vA:
0.0
5eeuS-1v7vA:
6.35
5eeuT-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.43A 5eevN-1v7vA:
0.7
5eevO-1v7vA:
0.7
5eevN-1v7vA:
6.35
5eevO-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.44A 5eevP-1v7vA:
0.0
5eevQ-1v7vA:
0.0
5eevP-1v7vA:
6.35
5eevQ-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.40A 5eevS-1v7vA:
0.0
5eevT-1v7vA:
0.0
5eevS-1v7vA:
6.35
5eevT-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.43A 5eewN-1v7vA:
0.7
5eewO-1v7vA:
0.3
5eewN-1v7vA:
6.35
5eewO-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.43A 5eewP-1v7vA:
0.3
5eewQ-1v7vA:
0.0
5eewP-1v7vA:
6.35
5eewQ-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.41A 5eewS-1v7vA:
0.0
5eewT-1v7vA:
0.0
5eewS-1v7vA:
6.35
5eewT-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.42A 5eexN-1v7vA:
0.7
5eexO-1v7vA:
undetectable
5eexN-1v7vA:
6.35
5eexO-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.44A 5eexP-1v7vA:
0.3
5eexQ-1v7vA:
0.3
5eexP-1v7vA:
6.35
5eexQ-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.40A 5eexS-1v7vA:
0.0
5eexT-1v7vA:
0.0
5eexS-1v7vA:
6.35
5eexT-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.43A 5eeyN-1v7vA:
0.7
5eeyO-1v7vA:
0.4
5eeyN-1v7vA:
6.35
5eeyO-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.44A 5eeyP-1v7vA:
0.3
5eeyQ-1v7vA:
0.3
5eeyP-1v7vA:
6.35
5eeyQ-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.40A 5eeyS-1v7vA:
0.0
5eeyT-1v7vA:
0.0
5eeyS-1v7vA:
6.35
5eeyT-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.43A 5eezN-1v7vA:
0.7
5eezO-1v7vA:
0.4
5eezN-1v7vA:
6.35
5eezO-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.44A 5eezP-1v7vA:
0.3
5eezQ-1v7vA:
undetectable
5eezP-1v7vA:
6.35
5eezQ-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.40A 5eezS-1v7vA:
0.0
5eezT-1v7vA:
0.0
5eezS-1v7vA:
6.35
5eezT-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.43A 5ef0N-1v7vA:
0.7
5ef0O-1v7vA:
0.7
5ef0N-1v7vA:
6.35
5ef0O-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.44A 5ef0P-1v7vA:
0.3
5ef0Q-1v7vA:
undetectable
5ef0P-1v7vA:
6.35
5ef0Q-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.40A 5ef0S-1v7vA:
0.0
5ef0T-1v7vA:
0.0
5ef0S-1v7vA:
6.35
5ef0T-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.43A 5ef1N-1v7vA:
undetectable
5ef1O-1v7vA:
0.3
5ef1N-1v7vA:
6.35
5ef1O-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.44A 5ef1P-1v7vA:
0.0
5ef1Q-1v7vA:
0.0
5ef1P-1v7vA:
6.35
5ef1Q-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.40A 5ef1S-1v7vA:
0.0
5ef1T-1v7vA:
0.0
5ef1S-1v7vA:
6.35
5ef1T-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.43A 5ef2N-1v7vA:
0.3
5ef2O-1v7vA:
0.3
5ef2N-1v7vA:
6.35
5ef2O-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.44A 5ef2P-1v7vA:
0.0
5ef2Q-1v7vA:
0.0
5ef2P-1v7vA:
6.35
5ef2Q-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.40A 5ef2S-1v7vA:
0.0
5ef2T-1v7vA:
0.0
5ef2S-1v7vA:
6.35
5ef2T-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.43A 5ef3N-1v7vA:
0.3
5ef3O-1v7vA:
undetectable
5ef3N-1v7vA:
6.35
5ef3O-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.44A 5ef3P-1v7vA:
0.0
5ef3Q-1v7vA:
0.0
5ef3P-1v7vA:
6.35
5ef3Q-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 419
HIS A 418
HIS A 385
THR A 423
ILE A 420
None
1.40A 5ef3S-1v7vA:
0.0
5ef3T-1v7vA:
0.0
5ef3S-1v7vA:
6.35
5ef3T-1v7vA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 732
GLY A 729
SER A 728
LEU A 733
GLU A 441
None
1.30A 5hwkA-1v7vA:
undetectable
5hwkA-1v7vA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 10 GLY A 732
GLY A 729
SER A 728
LEU A 733
GLU A 441
None
1.30A 5hwkB-1v7vA:
0.0
5hwkB-1v7vA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_A_ADNA401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 7 GLY A 610
ALA A 649
ASP A 602
PHE A 606
None
1.00A 5mvsA-1v7vA:
2.1
5mvsA-1v7vA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 GLY A 610
ALA A 649
ASP A 602
PHE A 606
None
0.98A 5mvsB-1v7vA:
undetectable
5mvsB-1v7vA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_1
(TETRACYCLINE
DESTRUCTASE TET(50))
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 5 ASP A 350
ARG A 333
LEU A 582
MET A 503
None
1.13A 5tuiB-1v7vA:
0.4
5tuiB-1v7vA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 9 GLY A 783
VAL A 798
ILE A 785
GLY A 732
PHE A 746
None
0.99A 5vkqC-1v7vA:
2.7
5vkqD-1v7vA:
2.7
5vkqC-1v7vA:
17.30
5vkqD-1v7vA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ALA A 652
LEU A 585
MET A 503
THR A 709
LEU A 669
None
1.02A 5x24A-1v7vA:
undetectable
5x24A-1v7vA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_Y_EF2Y501_1
(PROTEIN CEREBLON)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 7 THR A 327
TRP A 707
TRP A 320
PHE A   6
None
1.24A 5yizG-1v7vA:
0.0
5yizY-1v7vA:
0.0
5yizG-1v7vA:
7.60
5yizY-1v7vA:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_K_EF2K501_1
(PROTEIN CEREBLON)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 7 TRP A 320
PHE A   6
THR A 327
TRP A 707
None
1.25A 5yj0k-1v7vA:
0.0
5yj0t-1v7vA:
0.0
5yj0k-1v7vA:
7.60
5yj0t-1v7vA:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_Y_EF2Y501_1
(PROTEIN CEREBLON)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 7 THR A 327
TRP A 707
TRP A 320
PHE A   6
None
1.25A 5yj0G-1v7vA:
0.0
5yj0Y-1v7vA:
0.0
5yj0G-1v7vA:
7.60
5yj0Y-1v7vA:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_K_6ELK501_0
(PROTEIN CEREBLON)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 7 TRP A 320
PHE A   6
THR A 327
TRP A 707
None
1.22A 5yj1k-1v7vA:
0.0
5yj1t-1v7vA:
0.0
5yj1k-1v7vA:
8.51
5yj1t-1v7vA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_Y_6ELY501_0
(PROTEIN CEREBLON)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 7 THR A 327
TRP A 707
TRP A 320
PHE A   6
None
1.23A 5yj1G-1v7vA:
0.0
5yj1Y-1v7vA:
0.0
5yj1G-1v7vA:
8.51
5yj1Y-1v7vA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
3 / 3 VAL A 631
TYR A 632
GLU A 637
None
0.99A 5zmqD-1v7vA:
undetectable
5zmqE-1v7vA:
undetectable
5zmqD-1v7vA:
12.20
5zmqE-1v7vA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
5 / 12 ILE A 435
TYR A 348
GLY A 381
ALA A 469
LEU A 470
None
1.00A 5zwrA-1v7vA:
undetectable
5zwrA-1v7vA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 6 GLY A   4
THR A  16
GLN A  99
TYR A   5
None
1.21A 6ag0A-1v7vA:
undetectable
6ag0A-1v7vA:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 6 GLY A   4
THR A  16
GLN A  99
TYR A   5
None
1.22A 6ag0C-1v7vA:
undetectable
6ag0C-1v7vA:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 6 GLN A 353
VAL A 329
LEU A 507
PRO A 433
None
1.10A 6brdB-1v7vA:
undetectable
6brdB-1v7vA:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 THR A 709
GLN A 324
THR A 327
SER A 336
None
1.14A 6c06C-1v7vA:
undetectable
6c06C-1v7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 HIS A 385
SER A 425
SER A 501
ASP A 492
None
1.18A 6fbnB-1v7vA:
undetectable
6fbnB-1v7vA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 HIS A 385
SER A 425
SER A 501
ASP A 492
None
1.15A 6fboA-1v7vA:
undetectable
6fboA-1v7vA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 8 HIS A 385
SER A 425
SER A 501
ASP A 492
None
1.16A 6fcdA-1v7vA:
undetectable
6fcdA-1v7vA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus)
4 / 4 MET A 693
GLY A 694
HIS A 612
GLY A 634
None
1.47A 6fgdA-1v7vA:
undetectable
6fgdA-1v7vA:
18.44