SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		3 / 3 TRP A 180
ALA A 154
VAL A 178
 None
 0.93A 1c4dC-1v9cA:
undetectable
1c4dD-1v9cA:
undetectable		 1c4dC-1v9cA:
7.83
1c4dD-1v9cA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 1c9sA-1v9cA:
undetectable
1c9sK-1v9cA:
0.0		 1c9sA-1v9cA:
19.25
1c9sK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.14A 1c9sA-1v9cA:
undetectable
1c9sB-1v9cA:
undetectable		 1c9sA-1v9cA:
19.25
1c9sB-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 1c9sB-1v9cA:
undetectable
1c9sC-1v9cA:
undetectable		 1c9sB-1v9cA:
19.25
1c9sC-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.20A 1c9sC-1v9cA:
undetectable
1c9sD-1v9cA:
undetectable		 1c9sC-1v9cA:
19.25
1c9sD-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.14A 1c9sD-1v9cA:
undetectable
1c9sE-1v9cA:
undetectable		 1c9sD-1v9cA:
19.25
1c9sE-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 1c9sE-1v9cA:
undetectable
1c9sF-1v9cA:
undetectable		 1c9sE-1v9cA:
19.25
1c9sF-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.19A 1c9sF-1v9cA:
undetectable
1c9sG-1v9cA:
undetectable		 1c9sF-1v9cA:
19.25
1c9sG-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 1c9sG-1v9cA:
undetectable
1c9sH-1v9cA:
undetectable		 1c9sG-1v9cA:
19.25
1c9sH-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 1c9sH-1v9cA:
undetectable
1c9sI-1v9cA:
undetectable		 1c9sH-1v9cA:
19.25
1c9sI-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 1c9sJ-1v9cA:
undetectable
1c9sK-1v9cA:
0.0		 1c9sJ-1v9cA:
19.25
1c9sK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.13A 1c9sL-1v9cA:
undetectable
1c9sM-1v9cA:
undetectable		 1c9sL-1v9cA:
19.25
1c9sM-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 1c9sM-1v9cA:
undetectable
1c9sN-1v9cA:
undetectable		 1c9sM-1v9cA:
19.25
1c9sN-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.12A 1c9sN-1v9cA:
undetectable
1c9sO-1v9cA:
undetectable		 1c9sN-1v9cA:
19.25
1c9sO-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 1c9sO-1v9cA:
undetectable
1c9sP-1v9cA:
undetectable		 1c9sO-1v9cA:
19.25
1c9sP-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.13A 1c9sP-1v9cA:
undetectable
1c9sQ-1v9cA:
undetectable		 1c9sP-1v9cA:
19.25
1c9sQ-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.12A 1c9sQ-1v9cA:
undetectable
1c9sR-1v9cA:
undetectable		 1c9sQ-1v9cA:
19.25
1c9sR-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.12A 1c9sR-1v9cA:
undetectable
1c9sS-1v9cA:
undetectable		 1c9sR-1v9cA:
19.25
1c9sS-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.13A 1c9sS-1v9cA:
undetectable
1c9sT-1v9cA:
undetectable		 1c9sS-1v9cA:
19.25
1c9sT-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 7 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 1c9sT-1v9cA:
undetectable
1c9sU-1v9cA:
undetectable		 1c9sT-1v9cA:
19.25
1c9sU-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.12A 1c9sL-1v9cA:
undetectable
1c9sV-1v9cA:
undetectable		 1c9sL-1v9cA:
19.25
1c9sV-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 1gtfA-1v9cA:
0.0
1gtfK-1v9cA:
0.0		 1gtfA-1v9cA:
19.25
1gtfK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 1gtfA-1v9cA:
0.0
1gtfB-1v9cA:
0.0		 1gtfA-1v9cA:
19.25
1gtfB-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 1gtfB-1v9cA:
undetectable
1gtfC-1v9cA:
undetectable		 1gtfB-1v9cA:
19.25
1gtfC-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 1gtfC-1v9cA:
undetectable
1gtfD-1v9cA:
undetectable		 1gtfC-1v9cA:
19.25
1gtfD-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.14A 1gtfD-1v9cA:
undetectable
1gtfE-1v9cA:
undetectable		 1gtfD-1v9cA:
19.25
1gtfE-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 1gtfE-1v9cA:
undetectable
1gtfF-1v9cA:
undetectable		 1gtfE-1v9cA:
19.25
1gtfF-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 1gtfF-1v9cA:
undetectable
1gtfG-1v9cA:
undetectable		 1gtfF-1v9cA:
19.25
1gtfG-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 1gtfG-1v9cA:
undetectable
1gtfH-1v9cA:
undetectable		 1gtfG-1v9cA:
19.25
1gtfH-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.19A 1gtfH-1v9cA:
undetectable
1gtfI-1v9cA:
0.0		 1gtfH-1v9cA:
19.25
1gtfI-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 1gtfI-1v9cA:
0.0
1gtfJ-1v9cA:
undetectable		 1gtfI-1v9cA:
19.25
1gtfJ-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 7 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 1gtfL-1v9cA:
undetectable
1gtfM-1v9cA:
undetectable		 1gtfL-1v9cA:
19.25
1gtfM-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 1gtfM-1v9cA:
undetectable
1gtfN-1v9cA:
undetectable		 1gtfM-1v9cA:
19.25
1gtfN-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 8 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 1gtfN-1v9cA:
undetectable
1gtfO-1v9cA:
undetectable		 1gtfN-1v9cA:
19.25
1gtfO-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 1gtfO-1v9cA:
undetectable
1gtfP-1v9cA:
undetectable		 1gtfO-1v9cA:
19.25
1gtfP-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 1gtfP-1v9cA:
undetectable
1gtfQ-1v9cA:
undetectable		 1gtfP-1v9cA:
19.25
1gtfQ-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 1gtfR-1v9cA:
undetectable
1gtfS-1v9cA:
undetectable		 1gtfR-1v9cA:
19.25
1gtfS-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.13A 1gtfS-1v9cA:
undetectable
1gtfT-1v9cA:
undetectable		 1gtfS-1v9cA:
19.25
1gtfT-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 1gtfU-1v9cA:
0.0
1gtfV-1v9cA:
undetectable		 1gtfU-1v9cA:
19.25
1gtfV-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 1gtfL-1v9cA:
undetectable
1gtfV-1v9cA:
undetectable		 1gtfL-1v9cA:
19.25
1gtfV-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 8 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 1gtnA-1v9cA:
undetectable
1gtnB-1v9cA:
undetectable		 1gtnA-1v9cA:
19.25
1gtnB-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 1gtnB-1v9cA:
undetectable
1gtnC-1v9cA:
undetectable		 1gtnB-1v9cA:
19.25
1gtnC-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 1gtnG-1v9cA:
0.0
1gtnH-1v9cA:
undetectable		 1gtnG-1v9cA:
19.25
1gtnH-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.14A 1gtnH-1v9cA:
0.0
1gtnI-1v9cA:
undetectable		 1gtnH-1v9cA:
19.25
1gtnI-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 1gtnL-1v9cA:
undetectable
1gtnM-1v9cA:
undetectable		 1gtnL-1v9cA:
19.25
1gtnM-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.12A 1gtnN-1v9cA:
undetectable
1gtnO-1v9cA:
undetectable		 1gtnN-1v9cA:
19.25
1gtnO-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.13A 1gtnS-1v9cA:
undetectable
1gtnT-1v9cA:
undetectable		 1gtnS-1v9cA:
19.25
1gtnT-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.13A 1gtnU-1v9cA:
undetectable
1gtnV-1v9cA:
undetectable		 1gtnU-1v9cA:
19.25
1gtnV-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		4 / 4 ALA A 120
VAL A 117
ALA A 116
HIS A  98
 None
 1.19A 1q23A-1v9cA:
undetectable		 1q23A-1v9cA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 12 LEU A 197
LEU A 200
LEU A 203
ALA A 204
ILE A  69
 None
 0.77A 1s9pC-1v9cA:
undetectable		 1s9pC-1v9cA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		3 / 3 ALA A 154
VAL A 178
TRP A 180
 None
 0.84A 1tkqB-1v9cA:
undetectable		 1tkqB-1v9cA:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 1utdA-1v9cA:
undetectable
1utdB-1v9cA:
0.0		 1utdA-1v9cA:
19.25
1utdB-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 8 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 1utdB-1v9cA:
undetectable
1utdC-1v9cA:
undetectable		 1utdB-1v9cA:
19.25
1utdC-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 1utdC-1v9cA:
undetectable
1utdD-1v9cA:
undetectable		 1utdC-1v9cA:
19.25
1utdD-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.19A 1utdD-1v9cA:
0.0
1utdE-1v9cA:
undetectable		 1utdD-1v9cA:
19.25
1utdE-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 1utdE-1v9cA:
undetectable
1utdF-1v9cA:
undetectable		 1utdE-1v9cA:
19.25
1utdF-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 8 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.18A 1utdF-1v9cA:
undetectable
1utdG-1v9cA:
undetectable		 1utdF-1v9cA:
19.25
1utdG-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 1utdG-1v9cA:
undetectable
1utdH-1v9cA:
undetectable		 1utdG-1v9cA:
19.25
1utdH-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 1utdH-1v9cA:
0.0
1utdI-1v9cA:
undetectable		 1utdH-1v9cA:
19.25
1utdI-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 8 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 1utdJ-1v9cA:
undetectable
1utdK-1v9cA:
undetectable		 1utdJ-1v9cA:
19.25
1utdK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 1utdA-1v9cA:
undetectable
1utdK-1v9cA:
undetectable		 1utdA-1v9cA:
19.25
1utdK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.12A 1utdM-1v9cA:
undetectable
1utdN-1v9cA:
0.0		 1utdM-1v9cA:
19.25
1utdN-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 1utdN-1v9cA:
undetectable
1utdO-1v9cA:
undetectable		 1utdN-1v9cA:
19.25
1utdO-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 1utdQ-1v9cA:
undetectable
1utdR-1v9cA:
undetectable		 1utdQ-1v9cA:
19.25
1utdR-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 1utdT-1v9cA:
undetectable
1utdU-1v9cA:
undetectable		 1utdT-1v9cA:
19.25
1utdU-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		4 / 8 ILE A 130
GLY A  59
LEU A  60
LEU A 203
 None
 0.88A 2vctA-1v9cA:
undetectable		 2vctA-1v9cA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 12 ILE A 130
ALA A 154
LEU A 155
ALA A 142
VAL A 133
 None
 1.19A 2yvlC-1v9cA:
undetectable		 2yvlC-1v9cA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		4 / 7 VAL A  56
ILE A  63
GLN A  64
GLY A  66
 None
 0.90A 3bjwF-1v9cA:
undetectable		 3bjwF-1v9cA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 12 GLY A 208
ILE A 181
GLY A  59
ALA A 199
ALA A 196
 None
 1.01A 3sueA-1v9cA:
undetectable		 3sueA-1v9cA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 12 GLY A 208
ILE A 181
GLY A  59
ALA A 199
ALA A 196
 None
 0.97A 3sufB-1v9cA:
undetectable		 3sufB-1v9cA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 12 LEU A 197
LEU A 200
LEU A 203
ALA A 204
ALA A  58
 None
 1.06A 4fn9A-1v9cA:
undetectable		 4fn9A-1v9cA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 LEU A 197
LEU A 200
LEU A 157
ALA A 154
LEU A 155
 None
 0.99A 4wg0B-1v9cA:
undetectable
4wg0C-1v9cA:
undetectable
4wg0D-1v9cA:
undetectable		 4wg0B-1v9cA:
5.80
4wg0C-1v9cA:
5.80
4wg0D-1v9cA:
5.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 LEU A 197
LEU A 200
LEU A 157
ALA A 154
LEU A 155
 None
 1.01A 4wg0D-1v9cA:
undetectable
4wg0E-1v9cA:
undetectable
4wg0F-1v9cA:
undetectable		 4wg0D-1v9cA:
5.80
4wg0E-1v9cA:
5.80
4wg0F-1v9cA:
5.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 ALA A 154
LEU A 155
LEU A 157
LEU A 197
LEU A 200
 None
 1.00A 4wg0C-1v9cA:
undetectable
4wg0D-1v9cA:
undetectable
4wg0E-1v9cA:
undetectable		 4wg0C-1v9cA:
5.80
4wg0D-1v9cA:
5.80
4wg0E-1v9cA:
5.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 LEU A 197
LEU A 200
LEU A 157
ALA A 154
LEU A 155
 None
 1.00A 4wg0F-1v9cA:
undetectable
4wg0G-1v9cA:
undetectable
4wg0H-1v9cA:
undetectable		 4wg0F-1v9cA:
5.80
4wg0G-1v9cA:
5.80
4wg0H-1v9cA:
5.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 LEU A 197
LEU A 200
LEU A 157
ALA A 154
LEU A 155
 None
 1.02A 4wg0H-1v9cA:
undetectable
4wg0I-1v9cA:
undetectable
4wg0J-1v9cA:
undetectable		 4wg0H-1v9cA:
5.80
4wg0I-1v9cA:
5.80
4wg0J-1v9cA:
5.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 ALA A 154
LEU A 155
LEU A 157
LEU A 197
LEU A 200
 None
 1.02A 4wg0G-1v9cA:
undetectable
4wg0H-1v9cA:
undetectable
4wg0I-1v9cA:
undetectable		 4wg0G-1v9cA:
5.80
4wg0H-1v9cA:
5.80
4wg0I-1v9cA:
5.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 ALA A 154
LEU A 155
LEU A 157
LEU A 197
LEU A 200
 None
 0.99A 4wg0K-1v9cA:
undetectable
4wg0L-1v9cA:
undetectable
4wg0M-1v9cA:
undetectable		 4wg0K-1v9cA:
5.80
4wg0L-1v9cA:
5.80
4wg0M-1v9cA:
5.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 12 GLY A  79
LEU A  80
ALA A  73
ASP A  72
VAL A  92
 None
 0.90A 4wnwB-1v9cA:
undetectable		 4wnwB-1v9cA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eeuB-1v9cA:
undetectable
5eeuC-1v9cA:
undetectable		 5eeuB-1v9cA:
19.25
5eeuC-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eeuC-1v9cA:
undetectable
5eeuD-1v9cA:
0.0		 5eeuC-1v9cA:
19.25
5eeuD-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.21A 5eeuD-1v9cA:
undetectable
5eeuE-1v9cA:
undetectable		 5eeuD-1v9cA:
19.25
5eeuE-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 5eeuE-1v9cA:
undetectable
5eeuF-1v9cA:
undetectable		 5eeuE-1v9cA:
19.25
5eeuF-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eeuF-1v9cA:
undetectable
5eeuG-1v9cA:
0.0		 5eeuF-1v9cA:
19.25
5eeuG-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5eeuG-1v9cA:
undetectable
5eeuH-1v9cA:
undetectable		 5eeuG-1v9cA:
19.25
5eeuH-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5eeuJ-1v9cA:
undetectable
5eeuK-1v9cA:
0.0		 5eeuJ-1v9cA:
19.25
5eeuK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.19A 5eeuA-1v9cA:
undetectable
5eeuK-1v9cA:
undetectable		 5eeuA-1v9cA:
19.25
5eeuK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eeuL-1v9cA:
undetectable
5eeuV-1v9cA:
undetectable		 5eeuL-1v9cA:
19.25
5eeuV-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 5eeuL-1v9cA:
undetectable
5eeuM-1v9cA:
undetectable		 5eeuL-1v9cA:
19.25
5eeuM-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.12A 5eeuM-1v9cA:
undetectable
5eeuN-1v9cA:
undetectable		 5eeuM-1v9cA:
19.25
5eeuN-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eeuN-1v9cA:
undetectable
5eeuO-1v9cA:
undetectable		 5eeuN-1v9cA:
19.25
5eeuO-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5eeuO-1v9cA:
0.0
5eeuP-1v9cA:
undetectable		 5eeuO-1v9cA:
19.25
5eeuP-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 5eeuP-1v9cA:
undetectable
5eeuQ-1v9cA:
undetectable		 5eeuP-1v9cA:
19.25
5eeuQ-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5eeuQ-1v9cA:
undetectable
5eeuR-1v9cA:
undetectable		 5eeuQ-1v9cA:
19.25
5eeuR-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eeuT-1v9cA:
undetectable
5eeuU-1v9cA:
undetectable		 5eeuT-1v9cA:
19.25
5eeuU-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 5eeuU-1v9cA:
0.0
5eeuV-1v9cA:
undetectable		 5eeuU-1v9cA:
19.25
5eeuV-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eevB-1v9cA:
undetectable
5eevC-1v9cA:
undetectable		 5eevB-1v9cA:
19.25
5eevC-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5eevC-1v9cA:
0.0
5eevD-1v9cA:
0.0		 5eevC-1v9cA:
19.25
5eevD-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.21A 5eevD-1v9cA:
undetectable
5eevE-1v9cA:
undetectable		 5eevD-1v9cA:
19.25
5eevE-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 5eevE-1v9cA:
undetectable
5eevF-1v9cA:
undetectable		 5eevE-1v9cA:
19.25
5eevF-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eevF-1v9cA:
0.0
5eevG-1v9cA:
undetectable		 5eevF-1v9cA:
19.25
5eevG-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eevG-1v9cA:
undetectable
5eevH-1v9cA:
undetectable		 5eevG-1v9cA:
19.25
5eevH-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5eevH-1v9cA:
undetectable
5eevI-1v9cA:
0.0		 5eevH-1v9cA:
19.25
5eevI-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 12 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5eevI-1v9cA:
undetectable
5eevJ-1v9cA:
undetectable		 5eevI-1v9cA:
19.25
5eevJ-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5eevJ-1v9cA:
undetectable
5eevK-1v9cA:
undetectable		 5eevJ-1v9cA:
19.25
5eevK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.19A 5eevA-1v9cA:
undetectable
5eevK-1v9cA:
undetectable		 5eevA-1v9cA:
19.25
5eevK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 5eevL-1v9cA:
undetectable
5eevM-1v9cA:
undetectable		 5eevL-1v9cA:
19.25
5eevM-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.12A 5eevM-1v9cA:
undetectable
5eevN-1v9cA:
undetectable		 5eevM-1v9cA:
19.25
5eevN-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eevN-1v9cA:
undetectable
5eevO-1v9cA:
undetectable		 5eevN-1v9cA:
19.25
5eevO-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 5eevO-1v9cA:
0.0
5eevP-1v9cA:
undetectable		 5eevO-1v9cA:
19.25
5eevP-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 5eevP-1v9cA:
undetectable
5eevQ-1v9cA:
undetectable		 5eevP-1v9cA:
19.25
5eevQ-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5eevQ-1v9cA:
undetectable
5eevR-1v9cA:
undetectable		 5eevQ-1v9cA:
19.25
5eevR-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eevT-1v9cA:
undetectable
5eevU-1v9cA:
undetectable		 5eevT-1v9cA:
19.25
5eevU-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.13A 5eevU-1v9cA:
undetectable
5eevV-1v9cA:
undetectable		 5eevU-1v9cA:
19.25
5eevV-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eewB-1v9cA:
undetectable
5eewC-1v9cA:
undetectable		 5eewB-1v9cA:
19.25
5eewC-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5eewC-1v9cA:
undetectable
5eewD-1v9cA:
0.0		 5eewC-1v9cA:
19.25
5eewD-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.21A 5eewD-1v9cA:
undetectable
5eewE-1v9cA:
undetectable		 5eewD-1v9cA:
19.25
5eewE-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 5eewE-1v9cA:
undetectable
5eewF-1v9cA:
undetectable		 5eewE-1v9cA:
19.25
5eewF-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eewF-1v9cA:
0.0
5eewG-1v9cA:
0.0		 5eewF-1v9cA:
19.25
5eewG-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eewG-1v9cA:
undetectable
5eewH-1v9cA:
0.0		 5eewG-1v9cA:
19.25
5eewH-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5eewH-1v9cA:
0.0
5eewI-1v9cA:
0.0		 5eewH-1v9cA:
19.25
5eewI-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5eewJ-1v9cA:
0.0
5eewK-1v9cA:
0.0		 5eewJ-1v9cA:
19.25
5eewK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.18A 5eewA-1v9cA:
undetectable
5eewK-1v9cA:
undetectable		 5eewA-1v9cA:
19.25
5eewK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eewL-1v9cA:
undetectable
5eewM-1v9cA:
undetectable		 5eewL-1v9cA:
19.25
5eewM-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.12A 5eewM-1v9cA:
undetectable
5eewN-1v9cA:
undetectable		 5eewM-1v9cA:
19.25
5eewN-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eewN-1v9cA:
undetectable
5eewO-1v9cA:
undetectable		 5eewN-1v9cA:
19.25
5eewO-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5eewO-1v9cA:
undetectable
5eewP-1v9cA:
0.0		 5eewO-1v9cA:
19.25
5eewP-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 5eewP-1v9cA:
undetectable
5eewQ-1v9cA:
undetectable		 5eewP-1v9cA:
19.25
5eewQ-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 5eewQ-1v9cA:
undetectable
5eewR-1v9cA:
undetectable		 5eewQ-1v9cA:
19.25
5eewR-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eewT-1v9cA:
undetectable
5eewU-1v9cA:
undetectable		 5eewT-1v9cA:
19.25
5eewU-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.13A 5eewU-1v9cA:
undetectable
5eewV-1v9cA:
undetectable		 5eewU-1v9cA:
19.25
5eewV-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eexB-1v9cA:
undetectable
5eexC-1v9cA:
undetectable		 5eexB-1v9cA:
19.25
5eexC-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5eexC-1v9cA:
0.0
5eexD-1v9cA:
0.0		 5eexC-1v9cA:
19.25
5eexD-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.21A 5eexD-1v9cA:
undetectable
5eexE-1v9cA:
undetectable		 5eexD-1v9cA:
19.25
5eexE-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 5eexE-1v9cA:
undetectable
5eexF-1v9cA:
undetectable		 5eexE-1v9cA:
19.25
5eexF-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eexF-1v9cA:
0.0
5eexG-1v9cA:
undetectable		 5eexF-1v9cA:
19.25
5eexG-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eexG-1v9cA:
0.0
5eexH-1v9cA:
0.0		 5eexG-1v9cA:
19.25
5eexH-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5eexH-1v9cA:
undetectable
5eexI-1v9cA:
undetectable		 5eexH-1v9cA:
19.25
5eexI-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eexI-1v9cA:
undetectable
5eexJ-1v9cA:
undetectable		 5eexI-1v9cA:
19.25
5eexJ-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5eexJ-1v9cA:
undetectable
5eexK-1v9cA:
undetectable		 5eexJ-1v9cA:
19.25
5eexK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.19A 5eexA-1v9cA:
undetectable
5eexK-1v9cA:
undetectable		 5eexA-1v9cA:
19.25
5eexK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 5eexL-1v9cA:
undetectable
5eexV-1v9cA:
undetectable		 5eexL-1v9cA:
19.25
5eexV-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eexL-1v9cA:
undetectable
5eexM-1v9cA:
undetectable		 5eexL-1v9cA:
19.25
5eexM-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.11A 5eexM-1v9cA:
undetectable
5eexN-1v9cA:
undetectable		 5eexM-1v9cA:
19.25
5eexN-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eexN-1v9cA:
undetectable
5eexO-1v9cA:
undetectable		 5eexN-1v9cA:
19.25
5eexO-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5eexO-1v9cA:
undetectable
5eexP-1v9cA:
0.0		 5eexO-1v9cA:
19.25
5eexP-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 5eexP-1v9cA:
undetectable
5eexQ-1v9cA:
undetectable		 5eexP-1v9cA:
19.25
5eexQ-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 5eexQ-1v9cA:
undetectable
5eexR-1v9cA:
undetectable		 5eexQ-1v9cA:
19.25
5eexR-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eexT-1v9cA:
undetectable
5eexU-1v9cA:
undetectable		 5eexT-1v9cA:
19.25
5eexU-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.13A 5eexU-1v9cA:
undetectable
5eexV-1v9cA:
undetectable		 5eexU-1v9cA:
19.25
5eexV-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5eeyB-1v9cA:
undetectable
5eeyC-1v9cA:
undetectable		 5eeyB-1v9cA:
19.25
5eeyC-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eeyC-1v9cA:
0.0
5eeyD-1v9cA:
0.0		 5eeyC-1v9cA:
19.25
5eeyD-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.21A 5eeyD-1v9cA:
undetectable
5eeyE-1v9cA:
undetectable		 5eeyD-1v9cA:
19.25
5eeyE-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 5eeyE-1v9cA:
undetectable
5eeyF-1v9cA:
undetectable		 5eeyE-1v9cA:
19.25
5eeyF-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eeyF-1v9cA:
0.0
5eeyG-1v9cA:
0.0		 5eeyF-1v9cA:
19.25
5eeyG-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eeyG-1v9cA:
0.0
5eeyH-1v9cA:
0.0		 5eeyG-1v9cA:
19.25
5eeyH-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5eeyH-1v9cA:
0.0
5eeyI-1v9cA:
0.0		 5eeyH-1v9cA:
19.25
5eeyI-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eeyI-1v9cA:
undetectable
5eeyJ-1v9cA:
undetectable		 5eeyI-1v9cA:
19.25
5eeyJ-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5eeyJ-1v9cA:
undetectable
5eeyK-1v9cA:
0.0		 5eeyJ-1v9cA:
19.25
5eeyK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.18A 5eeyA-1v9cA:
undetectable
5eeyK-1v9cA:
undetectable		 5eeyA-1v9cA:
19.25
5eeyK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eeyL-1v9cA:
undetectable
5eeyV-1v9cA:
undetectable		 5eeyL-1v9cA:
19.25
5eeyV-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eeyL-1v9cA:
undetectable
5eeyM-1v9cA:
undetectable		 5eeyL-1v9cA:
19.25
5eeyM-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.11A 5eeyM-1v9cA:
undetectable
5eeyN-1v9cA:
undetectable		 5eeyM-1v9cA:
19.25
5eeyN-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eeyN-1v9cA:
undetectable
5eeyO-1v9cA:
undetectable		 5eeyN-1v9cA:
19.25
5eeyO-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5eeyO-1v9cA:
0.0
5eeyP-1v9cA:
0.0		 5eeyO-1v9cA:
19.25
5eeyP-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 5eeyP-1v9cA:
undetectable
5eeyQ-1v9cA:
undetectable		 5eeyP-1v9cA:
19.25
5eeyQ-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 5eeyQ-1v9cA:
undetectable
5eeyR-1v9cA:
undetectable		 5eeyQ-1v9cA:
19.25
5eeyR-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eeyT-1v9cA:
undetectable
5eeyU-1v9cA:
undetectable		 5eeyT-1v9cA:
19.25
5eeyU-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.13A 5eeyU-1v9cA:
undetectable
5eeyV-1v9cA:
undetectable		 5eeyU-1v9cA:
19.25
5eeyV-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eezB-1v9cA:
undetectable
5eezC-1v9cA:
0.0		 5eezB-1v9cA:
19.25
5eezC-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5eezC-1v9cA:
undetectable
5eezD-1v9cA:
0.0		 5eezC-1v9cA:
19.25
5eezD-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.21A 5eezD-1v9cA:
undetectable
5eezE-1v9cA:
undetectable		 5eezD-1v9cA:
19.25
5eezE-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 5eezE-1v9cA:
undetectable
5eezF-1v9cA:
undetectable		 5eezE-1v9cA:
19.25
5eezF-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eezF-1v9cA:
0.0
5eezG-1v9cA:
undetectable		 5eezF-1v9cA:
19.25
5eezG-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5eezG-1v9cA:
0.0
5eezH-1v9cA:
0.0		 5eezG-1v9cA:
19.25
5eezH-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5eezH-1v9cA:
0.0
5eezI-1v9cA:
undetectable		 5eezH-1v9cA:
19.25
5eezI-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5eezI-1v9cA:
undetectable
5eezJ-1v9cA:
undetectable		 5eezI-1v9cA:
19.25
5eezJ-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5eezJ-1v9cA:
undetectable
5eezK-1v9cA:
undetectable		 5eezJ-1v9cA:
19.25
5eezK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.19A 5eezA-1v9cA:
undetectable
5eezK-1v9cA:
undetectable		 5eezA-1v9cA:
19.25
5eezK-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 8 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 5eezL-1v9cA:
undetectable
5eezV-1v9cA:
undetectable		 5eezL-1v9cA:
19.25
5eezV-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eezL-1v9cA:
undetectable
5eezM-1v9cA:
undetectable		 5eezL-1v9cA:
19.25
5eezM-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.11A 5eezM-1v9cA:
undetectable
5eezN-1v9cA:
undetectable		 5eezM-1v9cA:
19.25
5eezN-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eezN-1v9cA:
undetectable
5eezO-1v9cA:
undetectable		 5eezN-1v9cA:
19.25
5eezO-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5eezO-1v9cA:
0.0
5eezP-1v9cA:
0.0		 5eezO-1v9cA:
19.25
5eezP-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5eezP-1v9cA:
undetectable
5eezQ-1v9cA:
undetectable		 5eezP-1v9cA:
19.25
5eezQ-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 5eezQ-1v9cA:
undetectable
5eezR-1v9cA:
undetectable		 5eezQ-1v9cA:
19.25
5eezR-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5eezT-1v9cA:
undetectable
5eezU-1v9cA:
undetectable		 5eezT-1v9cA:
19.25
5eezU-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.13A 5eezU-1v9cA:
0.0
5eezV-1v9cA:
0.0		 5eezU-1v9cA:
19.25
5eezV-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5ef0B-1v9cA:
undetectable
5ef0C-1v9cA:
undetectable		 5ef0B-1v9cA:
19.25
5ef0C-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5ef0C-1v9cA:
0.0
5ef0D-1v9cA:
0.0		 5ef0C-1v9cA:
19.25
5ef0D-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.21A 5ef0D-1v9cA:
undetectable
5ef0E-1v9cA:
undetectable		 5ef0D-1v9cA:
19.25
5ef0E-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 5ef0E-1v9cA:
undetectable
5ef0F-1v9cA:
undetectable		 5ef0E-1v9cA:
19.25
5ef0F-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5ef0F-1v9cA:
0.0
5ef0G-1v9cA:
undetectable		 5ef0F-1v9cA:
19.25
5ef0G-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5ef0G-1v9cA:
undetectable
5ef0H-1v9cA:
0.0		 5ef0G-1v9cA:
19.25
5ef0H-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5ef0H-1v9cA:
0.0
5ef0I-1v9cA:
0.0		 5ef0H-1v9cA:
19.25
5ef0I-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5ef0I-1v9cA:
undetectable
5ef0J-1v9cA:
undetectable		 5ef0I-1v9cA:
19.25
5ef0J-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5ef0J-1v9cA:
0.0
5ef0K-1v9cA:
0.0		 5ef0J-1v9cA:
19.25
5ef0K-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.19A 5ef0A-1v9cA:
undetectable
5ef0K-1v9cA:
undetectable		 5ef0A-1v9cA:
19.25
5ef0K-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 5ef0L-1v9cA:
undetectable
5ef0V-1v9cA:
undetectable		 5ef0L-1v9cA:
19.25
5ef0V-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5ef0L-1v9cA:
undetectable
5ef0M-1v9cA:
undetectable		 5ef0L-1v9cA:
19.25
5ef0M-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.11A 5ef0M-1v9cA:
undetectable
5ef0N-1v9cA:
undetectable		 5ef0M-1v9cA:
19.25
5ef0N-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5ef0N-1v9cA:
undetectable
5ef0O-1v9cA:
undetectable		 5ef0N-1v9cA:
19.25
5ef0O-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 5ef0O-1v9cA:
undetectable
5ef0P-1v9cA:
undetectable		 5ef0O-1v9cA:
19.25
5ef0P-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 5ef0P-1v9cA:
undetectable
5ef0Q-1v9cA:
undetectable		 5ef0P-1v9cA:
19.25
5ef0Q-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 5ef0Q-1v9cA:
undetectable
5ef0R-1v9cA:
undetectable		 5ef0Q-1v9cA:
19.25
5ef0R-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5ef0T-1v9cA:
undetectable
5ef0U-1v9cA:
undetectable		 5ef0T-1v9cA:
19.25
5ef0U-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.12A 5ef0U-1v9cA:
undetectable
5ef0V-1v9cA:
0.0		 5ef0U-1v9cA:
19.25
5ef0V-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5ef1B-1v9cA:
undetectable
5ef1C-1v9cA:
undetectable		 5ef1B-1v9cA:
19.25
5ef1C-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5ef1C-1v9cA:
undetectable
5ef1D-1v9cA:
0.0		 5ef1C-1v9cA:
19.25
5ef1D-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.21A 5ef1D-1v9cA:
undetectable
5ef1E-1v9cA:
undetectable		 5ef1D-1v9cA:
19.25
5ef1E-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 5ef1E-1v9cA:
undetectable
5ef1F-1v9cA:
undetectable		 5ef1E-1v9cA:
19.25
5ef1F-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5ef1F-1v9cA:
0.0
5ef1G-1v9cA:
undetectable		 5ef1F-1v9cA:
19.25
5ef1G-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5ef1G-1v9cA:
undetectable
5ef1H-1v9cA:
0.0		 5ef1G-1v9cA:
19.25
5ef1H-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5ef1H-1v9cA:
undetectable
5ef1I-1v9cA:
0.0		 5ef1H-1v9cA:
19.25
5ef1I-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5ef1I-1v9cA:
undetectable
5ef1J-1v9cA:
undetectable		 5ef1I-1v9cA:
19.25
5ef1J-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5ef1J-1v9cA:
undetectable
5ef1K-1v9cA:
undetectable		 5ef1J-1v9cA:
19.25
5ef1K-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.19A 5ef1A-1v9cA:
undetectable
5ef1K-1v9cA:
undetectable		 5ef1A-1v9cA:
19.25
5ef1K-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 8 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 5ef1L-1v9cA:
undetectable
5ef1V-1v9cA:
undetectable		 5ef1L-1v9cA:
19.25
5ef1V-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 5ef1L-1v9cA:
undetectable
5ef1M-1v9cA:
undetectable		 5ef1L-1v9cA:
19.25
5ef1M-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.11A 5ef1M-1v9cA:
undetectable
5ef1N-1v9cA:
undetectable		 5ef1M-1v9cA:
19.25
5ef1N-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5ef1N-1v9cA:
undetectable
5ef1O-1v9cA:
undetectable		 5ef1N-1v9cA:
19.25
5ef1O-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5ef1O-1v9cA:
undetectable
5ef1P-1v9cA:
undetectable		 5ef1O-1v9cA:
19.25
5ef1P-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 5ef1P-1v9cA:
undetectable
5ef1Q-1v9cA:
undetectable		 5ef1P-1v9cA:
19.25
5ef1Q-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 5ef1Q-1v9cA:
undetectable
5ef1R-1v9cA:
undetectable		 5ef1Q-1v9cA:
19.25
5ef1R-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5ef1T-1v9cA:
undetectable
5ef1U-1v9cA:
undetectable		 5ef1T-1v9cA:
19.25
5ef1U-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.13A 5ef1U-1v9cA:
undetectable
5ef1V-1v9cA:
0.0		 5ef1U-1v9cA:
19.25
5ef1V-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5ef2B-1v9cA:
undetectable
5ef2C-1v9cA:
undetectable		 5ef2B-1v9cA:
19.25
5ef2C-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5ef2C-1v9cA:
0.0
5ef2D-1v9cA:
0.0		 5ef2C-1v9cA:
19.25
5ef2D-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.21A 5ef2D-1v9cA:
undetectable
5ef2E-1v9cA:
undetectable		 5ef2D-1v9cA:
19.25
5ef2E-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 5ef2E-1v9cA:
undetectable
5ef2F-1v9cA:
undetectable		 5ef2E-1v9cA:
19.25
5ef2F-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5ef2F-1v9cA:
0.0
5ef2G-1v9cA:
undetectable		 5ef2F-1v9cA:
19.25
5ef2G-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5ef2G-1v9cA:
undetectable
5ef2H-1v9cA:
0.0		 5ef2G-1v9cA:
19.25
5ef2H-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5ef2H-1v9cA:
undetectable
5ef2I-1v9cA:
undetectable		 5ef2H-1v9cA:
19.25
5ef2I-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5ef2I-1v9cA:
undetectable
5ef2J-1v9cA:
undetectable		 5ef2I-1v9cA:
19.25
5ef2J-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5ef2J-1v9cA:
undetectable
5ef2K-1v9cA:
0.0		 5ef2J-1v9cA:
19.25
5ef2K-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.19A 5ef2A-1v9cA:
undetectable
5ef2K-1v9cA:
undetectable		 5ef2A-1v9cA:
19.25
5ef2K-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 8 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.15A 5ef2L-1v9cA:
undetectable
5ef2V-1v9cA:
undetectable		 5ef2L-1v9cA:
19.25
5ef2V-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 5ef2L-1v9cA:
undetectable
5ef2M-1v9cA:
undetectable		 5ef2L-1v9cA:
19.25
5ef2M-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.11A 5ef2M-1v9cA:
undetectable
5ef2N-1v9cA:
undetectable		 5ef2M-1v9cA:
19.25
5ef2N-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5ef2N-1v9cA:
undetectable
5ef2O-1v9cA:
undetectable		 5ef2N-1v9cA:
19.25
5ef2O-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5ef2O-1v9cA:
undetectable
5ef2P-1v9cA:
undetectable		 5ef2O-1v9cA:
19.25
5ef2P-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 5ef2P-1v9cA:
undetectable
5ef2Q-1v9cA:
undetectable		 5ef2P-1v9cA:
19.25
5ef2Q-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 5ef2Q-1v9cA:
undetectable
5ef2R-1v9cA:
undetectable		 5ef2Q-1v9cA:
19.25
5ef2R-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5ef2T-1v9cA:
undetectable
5ef2U-1v9cA:
undetectable		 5ef2T-1v9cA:
19.25
5ef2U-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.13A 5ef2U-1v9cA:
undetectable
5ef2V-1v9cA:
undetectable		 5ef2U-1v9cA:
19.25
5ef2V-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5ef3B-1v9cA:
undetectable
5ef3C-1v9cA:
undetectable		 5ef3B-1v9cA:
19.25
5ef3C-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5ef3C-1v9cA:
0.0
5ef3D-1v9cA:
0.0		 5ef3C-1v9cA:
19.25
5ef3D-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.21A 5ef3D-1v9cA:
undetectable
5ef3E-1v9cA:
undetectable		 5ef3D-1v9cA:
19.25
5ef3E-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5ef3E-1v9cA:
undetectable
5ef3F-1v9cA:
undetectable		 5ef3E-1v9cA:
19.25
5ef3F-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5ef3F-1v9cA:
0.0
5ef3G-1v9cA:
undetectable		 5ef3F-1v9cA:
19.25
5ef3G-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.16A 5ef3G-1v9cA:
undetectable
5ef3H-1v9cA:
0.0		 5ef3G-1v9cA:
19.25
5ef3H-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5ef3H-1v9cA:
undetectable
5ef3I-1v9cA:
undetectable		 5ef3H-1v9cA:
19.25
5ef3I-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 11 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.17A 5ef3I-1v9cA:
undetectable
5ef3J-1v9cA:
undetectable		 5ef3I-1v9cA:
19.25
5ef3J-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 THR A  40
GLY A 188
ALA A 196
THR A  49
THR A 183
 None
 1.18A 5ef3J-1v9cA:
undetectable
5ef3K-1v9cA:
0.0		 5ef3J-1v9cA:
19.25
5ef3K-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.19A 5ef3A-1v9cA:
undetectable
5ef3K-1v9cA:
undetectable		 5ef3A-1v9cA:
19.25
5ef3K-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 5ef3L-1v9cA:
undetectable
5ef3M-1v9cA:
undetectable		 5ef3L-1v9cA:
19.25
5ef3M-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.11A 5ef3M-1v9cA:
undetectable
5ef3N-1v9cA:
undetectable		 5ef3M-1v9cA:
19.25
5ef3N-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.16A 5ef3N-1v9cA:
undetectable
5ef3O-1v9cA:
undetectable		 5ef3N-1v9cA:
19.25
5ef3O-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5ef3O-1v9cA:
undetectable
5ef3P-1v9cA:
0.0		 5ef3O-1v9cA:
19.25
5ef3P-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.17A 5ef3P-1v9cA:
undetectable
5ef3Q-1v9cA:
undetectable		 5ef3P-1v9cA:
19.25
5ef3Q-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 9 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.14A 5ef3Q-1v9cA:
undetectable
5ef3R-1v9cA:
undetectable		 5ef3Q-1v9cA:
19.25
5ef3R-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.15A 5ef3T-1v9cA:
undetectable
5ef3U-1v9cA:
undetectable		 5ef3T-1v9cA:
19.25
5ef3U-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 10 GLY A 188
ALA A 196
THR A  49
THR A 183
THR A  40
 None
 1.13A 5ef3U-1v9cA:
0.0
5ef3V-1v9cA:
undetectable		 5ef3U-1v9cA:
19.25
5ef3V-1v9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_2
(TUBULIN BETA-2B
CHAIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 12 LEU A  80
LEU A 200
MET A 159
THR A 183
ALA A 199
 None
 1.31A 5nm5B-1v9cA:
4.1		 5nm5B-1v9cA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		3 / 3 LEU A 203
ALA A 204
LEU A  28
 None
 0.55A 5uunB-1v9cA:
undetectable		 5uunB-1v9cA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 1v9c PRECORRIN-8X METHYL
MUTASE
(Thermus
thermophilus) 		5 / 12 GLY A 208
ILE A 181
GLY A  59
ALA A 199
ALA A 196
 None
 0.95A 6c2mD-1v9cA:
undetectable		 6c2mD-1v9cA:
17.56