SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v9d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1v9d DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 8 ILE A 874
ILE A 861
GLU A 863
VAL A 864
ILE A 923
 None
 1.14A 1linA-1v9dA:
undetectable		 1linA-1v9dA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1v9d DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		4 / 7 PHE A1069
ALA A 922
ILE A 861
ILE A 874
 None
 0.98A 1oniD-1v9dA:
undetectable
1oniF-1v9dA:
undetectable		 1oniD-1v9dA:
18.04
1oniF-1v9dA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 1v9d DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		3 / 3 ASP A 992
THR A1001
GLU A1134
 None
 0.81A 1pj7A-1v9dA:
undetectable		 1pj7A-1v9dA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_B_TOPB200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1v9d DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 12 ASN A 859
LEU A 869
ILE A 857
LEU A 877
PHE A 850
 None
 1.13A 3fl9B-1v9dA:
undetectable		 3fl9B-1v9dA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1v9d DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		5 / 11 ASP A1120
ASN A1123
LEU A1121
VAL A1027
ALA A1030
 None
 1.41A 3n23C-1v9dA:
undetectable		 3n23C-1v9dA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1v9d DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		4 / 6 PHE A 850
TYR A 854
VAL A 913
PHE A 906
 None
 1.15A 4a97E-1v9dA:
4.3		 4a97E-1v9dA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 1v9d DIAPHANOUS PROTEIN
HOMOLOG 1
(Mus
musculus) 		3 / 3 ASP A1064
ARG A 919
PRO A 914
 None
None
SO4  A1164 (-4.9A)
 1.02A 4wanC-1v9dA:
undetectable		 4wanC-1v9dA:
16.37