SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v9k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C
(Escherichia
coli) 		5 / 12 ALA A 112
GLY A 116
GLY A 115
LEU A 200
ARG A 208
 None
 0.87A 1eizA-1v9kA:
undetectable		 1eizA-1v9kA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C
(Escherichia
coli) 		4 / 7 LEU A 160
LEU A 152
MET A 172
LEU A 167
 None
 1.09A 1kt3A-1v9kA:
undetectable		 1kt3A-1v9kA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C
(Escherichia
coli) 		3 / 3 GLU A 217
THR A 218
LEU A 195
 None
 0.65A 1v8bC-1v9kA:
undetectable		 1v8bC-1v9kA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C
(Escherichia
coli) 		3 / 3 SER A 120
GLU A 204
ASP A 144
 None
 0.56A 2avdB-1v9kA:
undetectable		 2avdB-1v9kA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C
(Escherichia
coli) 		4 / 6 GLU A  98
ILE A 102
HIS A 141
VAL A 113
 None
 1.05A 4ejwB-1v9kA:
undetectable		 4ejwB-1v9kA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C
(Escherichia
coli) 		4 / 8 LEU A 105
LEU A 151
VAL A 153
ILE A 124
 None
 0.95A 4oj4A-1v9kA:
undetectable		 4oj4A-1v9kA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C
(Escherichia
coli) 		5 / 12 LEU A 137
LEU A 139
LEU A 127
LYS A 107
ILE A  95
 None
 1.08A 4x1yB-1v9kA:
undetectable		 4x1yB-1v9kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C
(Escherichia
coli) 		4 / 5 GLN A 249
PRO A 254
ILE A 255
ASP A 258
 None
 1.34A 4z4hA-1v9kA:
undetectable		 4z4hA-1v9kA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C
(Escherichia
coli) 		4 / 6 ALA A 251
VAL A 191
VAL A 232
HIS A 253
 None
 1.01A 5eckA-1v9kA:
undetectable		 5eckA-1v9kA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C
(Escherichia
coli) 		4 / 6 ALA A 251
VAL A 191
VAL A 232
HIS A 253
 None
 1.03A 5eckD-1v9kA:
undetectable		 5eckD-1v9kA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C
(Escherichia
coli) 		4 / 6 ALA A 251
VAL A 191
VAL A 232
HIS A 253
 None
 0.97A 5eclA-1v9kA:
undetectable		 5eclA-1v9kA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C
(Escherichia
coli) 		5 / 12 LEU A 137
LEU A 139
LEU A 127
LYS A 107
ILE A  95
 None
 1.04A 5itzB-1v9kA:
undetectable		 5itzB-1v9kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C
(Escherichia
coli) 		5 / 12 LEU A 200
ILE A 206
ASP A 258
LEU A 280
HIS A 242
 None
 1.48A 5nn8A-1v9kA:
undetectable		 5nn8A-1v9kA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_B_RBFB201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 1v9k RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE C
(Escherichia
coli) 		4 / 7 ARG A 316
TYR A 226
GLU A 224
LEU A 308
 None
 1.04A 5umwB-1v9kA:
0.0
5umwE-1v9kA:
0.0		 5umwB-1v9kA:
17.59
5umwE-1v9kA:
17.59