SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 7 ARG A 209
THR A 138
VAL A 124
ALA A 204
 None
 1.04A 1fo4B-1v9pA:
undetectable		 1fo4B-1v9pA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 8 LEU A 368
HIS A 360
VAL A 196
GLU A 387
 None
 1.00A 1jtvA-1v9pA:
undetectable		 1jtvA-1v9pA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 6 LYS A 218
ALA A 217
LEU A 221
VAL A  26
 None
 1.08A 1sn5A-1v9pA:
undetectable		 1sn5A-1v9pA:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 1v9p DNA LIGASE
(Thermus
filiformis) 		5 / 12 GLY A 206
VAL A 148
LEU A 122
SER A 123
LEU A 152
 None
None
None
AMP  A 700 ( 4.3A)
None
 1.26A 1ya4B-1v9pA:
2.5		 1ya4B-1v9pA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 6 ARG A 209
THR A 138
VAL A 124
ALA A 205
 None
 1.06A 2e1qA-1v9pA:
2.5		 2e1qA-1v9pA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 6 ARG A 209
THR A 138
VAL A 124
ALA A 205
 None
 1.06A 2e1qC-1v9pA:
undetectable		 2e1qC-1v9pA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 1v9p DNA LIGASE
(Thermus
filiformis) 		3 / 3 VAL A 518
VAL A 521
ASP A 448
 None
 0.77A 2fumD-1v9pA:
undetectable		 2fumD-1v9pA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 8 LEU A 152
ARG A 172
VAL A  76
GLY A 145
 None
 0.86A 2qd5B-1v9pA:
undetectable		 2qd5B-1v9pA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1v9p DNA LIGASE
(Thermus
filiformis) 		5 / 8 LEU A 526
LEU A 510
ALA A 539
LEU A 537
PHE A 567
 None
 1.43A 2vcvF-1v9pA:
undetectable		 2vcvF-1v9pA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 8 LEU A 247
LEU A 169
LEU A 237
ARG A 172
 None
 1.00A 2xn3A-1v9pA:
0.0
2xn3B-1v9pA:
0.0		 2xn3A-1v9pA:
19.39
2xn3B-1v9pA:
5.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 5 ARG A 535
MET A 533
THR A 532
LEU A 506
 None
 1.41A 3ag1J-1v9pA:
undetectable		 3ag1J-1v9pA:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 5 ARG A 535
MET A 533
THR A 532
LEU A 506
 None
 1.45A 3ag4J-1v9pA:
undetectable		 3ag4J-1v9pA:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 1v9p DNA LIGASE
(Thermus
filiformis) 		5 / 9 LEU A 152
ILE A 158
LEU A 208
SER A 207
LEU A 221
 None
 0.99A 3ai9X-1v9pA:
undetectable		 3ai9X-1v9pA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1v9p DNA LIGASE
(Thermus
filiformis) 		3 / 3 PRO A 406
LEU A 416
ARG A 424
 None
 0.60A 3aqiA-1v9pA:
undetectable		 3aqiA-1v9pA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 1v9p DNA LIGASE
(Thermus
filiformis) 		3 / 3 PRO A 406
LEU A 416
ARG A 424
 None
 0.75A 3aqiB-1v9pA:
undetectable		 3aqiB-1v9pA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 8 ARG A 209
THR A 138
VAL A 124
ALA A 205
 None
 1.01A 3ax7A-1v9pA:
undetectable		 3ax7A-1v9pA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1v9p DNA LIGASE
(Thermus
filiformis) 		5 / 9 ARG A 209
THR A 138
VAL A 124
ALA A 204
ALA A 205
 None
 1.16A 3ax7B-1v9pA:
0.0		 3ax7B-1v9pA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 8 ARG A 209
THR A 138
VAL A 124
ALA A 205
 None
 1.00A 3ax9A-1v9pA:
undetectable		 3ax9A-1v9pA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 6 ALA A 381
ILE A 385
VAL A 196
HIS A 360
 None
 0.91A 3nneG-1v9pA:
undetectable		 3nneG-1v9pA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 6 ARG A 209
THR A 138
ALA A 204
ALA A 205
 None
 1.15A 3ns1C-1v9pA:
undetectable		 3ns1C-1v9pA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 1v9p DNA LIGASE
(Thermus
filiformis) 		3 / 3 LYS A 421
ARG A 192
LYS A 198
 None
 1.49A 3okxA-1v9pA:
0.0		 3okxA-1v9pA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_A_T44A128_1
(TRANSTHYRETIN)		 1v9p DNA LIGASE
(Thermus
filiformis) 		5 / 9 LYS A 218
ALA A 217
LEU A 221
THR A 154
VAL A  26
 None
 1.41A 3ozkA-1v9pA:
0.2		 3ozkA-1v9pA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 7 ARG A 209
THR A 138
VAL A 124
ALA A 205
 None
 1.01A 3uniA-1v9pA:
undetectable		 3uniA-1v9pA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 1v9p DNA LIGASE
(Thermus
filiformis) 		3 / 3 ASP A  38
GLY A  65
TYR A  37
 None
 0.67A 3w9tC-1v9pA:
undetectable		 3w9tC-1v9pA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 1v9p DNA LIGASE
(Thermus
filiformis) 		3 / 3 ASP A  38
GLY A  65
TYR A  37
 None
 0.67A 3w9tG-1v9pA:
undetectable		 3w9tG-1v9pA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 8 LEU A 506
MET A 581
TYR A 473
TYR A 441
 None
 1.28A 3wipF-1v9pA:
undetectable
3wipJ-1v9pA:
undetectable		 3wipF-1v9pA:
16.07
3wipJ-1v9pA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 8 ILE A 155
ILE A 158
VAL A 124
GLY A 136
 None
 0.74A 4ac9C-1v9pA:
undetectable		 4ac9C-1v9pA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 8 ILE A 155
ILE A 158
VAL A 124
GLY A 136
 None
 0.75A 4acaC-1v9pA:
undetectable		 4acaC-1v9pA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 8 ILE A 155
ILE A 158
VAL A 124
GLY A 136
 None
 0.71A 4acbC-1v9pA:
undetectable		 4acbC-1v9pA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 8 GLY A 121
LEU A 122
VAL A 124
GLU A 174
 None
None
None
AMP  A 700 (-4.0A)
 0.92A 4fgzA-1v9pA:
undetectable		 4fgzA-1v9pA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 8 GLY A 121
LEU A 122
VAL A 124
GLU A 174
 None
None
None
AMP  A 700 (-4.0A)
 0.92A 4fgzB-1v9pA:
undetectable		 4fgzB-1v9pA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 1v9p DNA LIGASE
(Thermus
filiformis) 		5 / 12 LEU A 162
PHE A 252
PRO A 166
GLY A 229
LEU A 228
 None
 1.18A 4j7xB-1v9pA:
undetectable		 4j7xB-1v9pA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 1v9p DNA LIGASE
(Thermus
filiformis) 		3 / 3 GLU A 350
ARG A 278
HIS A 279
 None
 0.66A 4kf9A-1v9pA:
undetectable		 4kf9A-1v9pA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 1v9p DNA LIGASE
(Thermus
filiformis) 		5 / 12 ASP A 374
LEU A 325
LEU A 359
LEU A 368
ILE A 370
 None
 1.03A 4x1fA-1v9pA:
undetectable		 4x1fA-1v9pA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 1v9p DNA LIGASE
(Thermus
filiformis) 		5 / 12 ASP A 374
LEU A 325
LEU A 359
LEU A 368
ILE A 370
 None
 1.04A 4x1gA-1v9pA:
undetectable		 4x1gA-1v9pA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1v9p DNA LIGASE
(Thermus
filiformis) 		5 / 8 LEU A 536
ALA A 539
LEU A 562
ALA A 555
LEU A 526
 None
 0.87A 4z90A-1v9pA:
2.9
4z90B-1v9pA:
3.0
4z90C-1v9pA:
2.5
4z90D-1v9pA:
2.7
4z90E-1v9pA:
2.9		 4z90A-1v9pA:
20.18
4z90B-1v9pA:
20.18
4z90C-1v9pA:
20.18
4z90D-1v9pA:
20.18
4z90E-1v9pA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 5 SER A 501
ARG A 439
GLY A 453
GLU A 454
 None
 1.11A 5btiA-1v9pA:
undetectable
5btiB-1v9pA:
2.5		 5btiA-1v9pA:
23.96
5btiB-1v9pA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 5 SER A 501
ARG A 439
GLY A 453
GLU A 454
 None
 1.10A 5btiC-1v9pA:
undetectable
5btiD-1v9pA:
2.4		 5btiC-1v9pA:
23.96
5btiD-1v9pA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 5 THR A 216
ALA A 217
THR A 154
TYR A  22
 None
 1.29A 5ecmA-1v9pA:
undetectable		 5ecmA-1v9pA:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 5 LEU A 509
TYR A 511
LEU A 513
TYR A 441
 None
 1.18A 5ki6A-1v9pA:
undetectable		 5ki6A-1v9pA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 6 GLU A 552
ARG A 556
ALA A 555
LEU A 553
 None
 1.14A 5phhA-1v9pA:
undetectable		 5phhA-1v9pA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1v9p DNA LIGASE
(Thermus
filiformis) 		5 / 11 LEU A 152
ILE A 158
LEU A 208
SER A 207
LEU A 221
 None
 0.90A 5twjD-1v9pA:
undetectable		 5twjD-1v9pA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 5 THR A 224
GLU A 116
THR A 114
LEU A 245
 None
AMP  A 700 (-3.7A)
None
None
 1.30A 5utuH-1v9pA:
undetectable		 5utuH-1v9pA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 5 ARG A 535
MET A 533
THR A 532
LEU A 506
 None
 1.14A 5x19J-1v9pA:
undetectable		 5x19J-1v9pA:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 5 ARG A 535
MET A 533
THR A 532
LEU A 506
 None
 1.12A 5x1bJ-1v9pA:
undetectable		 5x1bJ-1v9pA:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 1v9p DNA LIGASE
(Thermus
filiformis) 		5 / 12 GLY A 145
THR A  72
ARG A  74
ARG A 209
LEU A 208
 None
 1.47A 6bp4A-1v9pA:
undetectable		 6bp4A-1v9pA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 5 ARG A 508
ALA A 446
TYR A 441
ILE A 449
 None
 1.41A 6g9bA-1v9pA:
undetectable
6g9bB-1v9pA:
undetectable		 6g9bA-1v9pA:
10.34
6g9bB-1v9pA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCX_A_ZMRA519_1
(NEURAMINIDASE)		 1v9p DNA LIGASE
(Thermus
filiformis) 		3 / 3 TRP A 405
ILE A 365
GLU A 190
 None
 0.83A 6hcxA-1v9pA:
undetectable		 6hcxA-1v9pA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1v9p DNA LIGASE
(Thermus
filiformis) 		4 / 5 ARG A 535
MET A 533
THR A 532
LEU A 506
 None
 1.44A 6nknJ-1v9pA:
undetectable		 6nknJ-1v9pA:
7.36