SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v9t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 1v9t CYCLOPHILIN B
(Escherichia
coli) 		5 / 9 LEU A 160
ILE A 159
ASN A  43
GLY A  39
ALA A 162
 None
 1.29A 1e7aA-1v9tA:
undetectable		 1e7aA-1v9tA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 1v9t CYCLOPHILIN B
(Escherichia
coli) 		3 / 3 PHE A 125
TYR A  41
TYR A  35
 None
 0.95A 1x70B-1v9tA:
undetectable		 1x70B-1v9tA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 1v9t CYCLOPHILIN B
(Escherichia
coli) 		4 / 5 LEU A  20
GLY A 126
PHE A 125
PHE A  32
 None
 1.16A 3smtA-1v9tA:
undetectable		 3smtA-1v9tA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 1v9t CYCLOPHILIN B
(Escherichia
coli) 		5 / 11 PHE A 103
PHE A  32
PHE A  46
ILE A 159
LEU A  18
 None
 1.11A 3t3rA-1v9tA:
undetectable		 3t3rA-1v9tA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1v9t CYCLOPHILIN B
(Escherichia
coli) 		3 / 3 GLN A 150
THR A 143
ASN A 151
 None
 0.81A 3v4tE-1v9tA:
0.0		 3v4tE-1v9tA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_F_AZ1F2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR-DAR)		 1v9t CYCLOPHILIN B
(Escherichia
coli) 		5 / 7 GLY A  86
PHE A 125
GLY A 126
VAL A 128
LEU A  20
 None
 0.82A 5izjB-1v9tA:
undetectable		 5izjB-1v9tA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1v9t CYCLOPHILIN B
(Escherichia
coli) 		3 / 3 VAL A 152
TYR A 149
GLN A 150
 None
 0.75A 5qgkA-1v9tA:
0.0		 5qgkA-1v9tA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1v9t CYCLOPHILIN B
(Escherichia
coli) 		3 / 3 VAL A 152
TYR A 149
GLN A 150
 None
 0.75A 5qgtA-1v9tA:
0.0		 5qgtA-1v9tA:
17.50