SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1v9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZUL_A_SAMA376_1 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	1v9x	POLY (ADP-RIBOSE) POLYMERASE (Arabidopsis thaliana)	3 / 3	SER A 3 GLU A 73 ASP A 71	None	0.73A	2zulA-1v9xA: undetectable	2zulA-1v9xA: 11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DMH_A_SAMA384_1 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	1v9x	POLY (ADP-RIBOSE) POLYMERASE (Arabidopsis thaliana)	3 / 3	SER A 3 GLU A 73 ASP A 71	None	0.68A	3dmhA-1v9xA: undetectable	3dmhA-1v9xA: 11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YNP_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	1v9x	POLY (ADP-RIBOSE) POLYMERASE (Arabidopsis thaliana)	5 / 12	HIS A 55 CYH A 23 LYS A 24 CYH A 26 ILE A 30	ZN A 200 (-3.1A) ZN A 200 (-2.3A) None ZN A 200 (-2.3A) None	1.37A	4ynpA-1v9xA: undetectable	4ynpA-1v9xA: 18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6INE_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	1v9x	POLY (ADP-RIBOSE) POLYMERASE (Arabidopsis thaliana)	5 / 12	HIS A 55 CYH A 23 LYS A 24 CYH A 26 ILE A 30	ZN A 200 (-3.1A) ZN A 200 (-2.3A) None ZN A 200 (-2.3A) None	1.45A	6ineA-1v9xA: undetectable	6ineA-1v9xA: 17.16

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZUL_A_SAMA376_1","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","1v9x","POLY (ADP-RIBOSE) POLYMERASE","Arabidopsis thaliana",3,"SER A   3;GLU A  73;ASP A  71","None","0.73A","2zulA-1v9xA:undetectable","2zulA-1v9xA:11.23"],["3DMH_A_SAMA384_1","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","1v9x","POLY (ADP-RIBOSE) POLYMERASE","Arabidopsis thaliana",3,"SER A   3;GLU A  73;ASP A  71","None","0.68A","3dmhA-1v9xA:undetectable","3dmhA-1v9xA:11.23"],["4YNP_A_SAMA2304_0","HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L","1v9x","POLY (ADP-RIBOSE) POLYMERASE","Arabidopsis thaliana",5,"HIS A  55;CYH A  23;LYS A  24;CYH A  26;ILE A  30"," ZN A 200 (-3.1A); ZN A 200 (-2.3A);None; ZN A 200 (-2.3A);None","1.37A","4ynpA-1v9xA:undetectable","4ynpA-1v9xA:18.58"],["6INE_A_SAMA2304_0","HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L","1v9x","POLY (ADP-RIBOSE) POLYMERASE","Arabidopsis thaliana",5,"HIS A  55;CYH A  23;LYS A  24;CYH A  26;ILE A  30"," ZN A 200 (-3.1A); ZN A 200 (-2.3A);None; ZN A 200 (-2.3A);None","1.45A","6ineA-1v9xA:undetectable","6ineA-1v9xA:17.16"]]