SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vaj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 1vaj HYPOTHETICAL PROTEIN
PH0010
(Pyrococcus
horikoshii) 		4 / 6 LYS A 203
VAL A  14
ILE A 190
ARG A  53
 None
 1.10A 1iepA-1vajA:
undetectable		 1iepA-1vajA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1vaj HYPOTHETICAL PROTEIN
PH0010
(Pyrococcus
horikoshii) 		4 / 7 ILE A  66
ARG A  92
LEU A 147
GLY A  64
 None
 0.89A 1mt1H-1vajA:
2.1
1mt1K-1vajA:
undetectable		 1mt1H-1vajA:
21.66
1mt1K-1vajA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 1vaj HYPOTHETICAL PROTEIN
PH0010
(Pyrococcus
horikoshii) 		5 / 12 PHE A 191
LEU A  13
VAL A 110
GLU A  43
LEU A  75
 None
 1.32A 2bxfB-1vajA:
undetectable		 2bxfB-1vajA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 1vaj HYPOTHETICAL PROTEIN
PH0010
(Pyrococcus
horikoshii) 		4 / 6 LYS A 203
VAL A  14
ILE A 190
ARG A  53
 None
 0.88A 2hyyA-1vajA:
undetectable		 2hyyA-1vajA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1vaj HYPOTHETICAL PROTEIN
PH0010
(Pyrococcus
horikoshii) 		4 / 4 CYH A 175
PRO A 121
THR A 165
ASP A 180
 None
 1.39A 3hlwA-1vajA:
0.0		 3hlwA-1vajA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1vaj HYPOTHETICAL PROTEIN
PH0010
(Pyrococcus
horikoshii) 		4 / 6 LYS A 203
VAL A  14
ILE A 190
ARG A  53
 None
 0.83A 3ms9A-1vajA:
undetectable		 3ms9A-1vajA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1vaj HYPOTHETICAL PROTEIN
PH0010
(Pyrococcus
horikoshii) 		4 / 6 LYS A 203
VAL A  14
ILE A 190
ARG A  53
 None
 0.83A 3mssA-1vajA:
undetectable		 3mssA-1vajA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1vaj HYPOTHETICAL PROTEIN
PH0010
(Pyrococcus
horikoshii) 		4 / 6 LYS A 203
VAL A  14
ILE A 190
ARG A  53
 None
 0.82A 3mssC-1vajA:
undetectable		 3mssC-1vajA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 1vaj HYPOTHETICAL PROTEIN
PH0010
(Pyrococcus
horikoshii) 		4 / 6 LYS A 203
VAL A  14
ILE A 190
ARG A  53
 None
 0.91A 3pyyA-1vajA:
undetectable		 3pyyA-1vajA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOA_A_ACRA1587_2
(TREHALOSE
SYNTHASE/AMYLASE
TRES)		 1vaj HYPOTHETICAL PROTEIN
PH0010
(Pyrococcus
horikoshii) 		3 / 3 ARG A  92
PHE A  93
PRO A  94
 None
 0.58A 3zoaB-1vajA:
undetectable		 3zoaB-1vajA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 1vaj HYPOTHETICAL PROTEIN
PH0010
(Pyrococcus
horikoshii) 		5 / 11 ALA A 188
LEU A 147
GLY A  67
ILE A 136
VAL A 108
 None
 1.10A 3zosA-1vajA:
undetectable
3zosB-1vajA:
undetectable		 3zosA-1vajA:
21.60
3zosB-1vajA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 1vaj HYPOTHETICAL PROTEIN
PH0010
(Pyrococcus
horikoshii) 		4 / 6 GLU A 107
THR A  50
GLN A 149
LEU A 111
 None
 1.24A 4qzuC-1vajA:
undetectable		 4qzuC-1vajA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 1vaj HYPOTHETICAL PROTEIN
PH0010
(Pyrococcus
horikoshii) 		4 / 5 LEU A 171
CYH A 166
THR A 165
GLY A 144
 None
 0.92A 6gtqA-1vajA:
undetectable		 6gtqA-1vajA:
21.13