SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vap'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1vap PHOSPHOLIPASE A2
(Agkistrodon
piscivorus) 		4 / 8 LEU A   2
GLY A  29
HIS A  47
PHE A  96
 None
 0.51A 1sv9A-1vapA:
21.6		 1sv9A-1vapA:
60.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 1vap PHOSPHOLIPASE A2
(Agkistrodon
piscivorus) 		6 / 7 GLY A  29
TRP A  30
HIS A  47
ASP A  48
TYR A  51
PRO A  59
 None
 0.73A 1th6A-1vapA:
21.6		 1th6A-1vapA:
60.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1vap PHOSPHOLIPASE A2
(Agkistrodon
piscivorus) 		6 / 7 GLY A  29
TRP A  30
HIS A  47
ASP A  48
TYR A  51
PRO A  59
 None
 0.72A 2armA-1vapA:
21.5		 2armA-1vapA:
60.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1vap PHOSPHOLIPASE A2
(Agkistrodon
piscivorus) 		5 / 10 LEU A   2
GLY A  29
HIS A  47
ASP A  48
PHE A  96
 None
 0.49A 2b17A-1vapA:
21.5		 2b17A-1vapA:
60.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1vap PHOSPHOLIPASE A2
(Agkistrodon
piscivorus) 		4 / 6 LEU A   2
HIS A  47
ASP A  48
TYR A  51
 None
 0.36A 2dpzA-1vapA:
21.8		 2dpzA-1vapA:
60.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1vap PHOSPHOLIPASE A2
(Agkistrodon
piscivorus) 		4 / 5 LEU A   2
SER A  22
GLY A  29
HIS A  47
 None
 0.39A 2otfA-1vapA:
21.8		 2otfA-1vapA:
60.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1vap PHOSPHOLIPASE A2
(Agkistrodon
piscivorus) 		5 / 5 HIS A  47
ASP A  48
TYR A  51
PRO A  59
LYS A  60
 None
 0.66A 3fo7A-1vapA:
21.5		 3fo7A-1vapA:
60.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 1vap PHOSPHOLIPASE A2
(Agkistrodon
piscivorus) 		4 / 5 HIS A  47
ASP A  48
TYR A  51
PRO A  59
 None
 0.37A 3h1xA-1vapA:
21.7		 3h1xA-1vapA:
60.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 1vap PHOSPHOLIPASE A2
(Agkistrodon
piscivorus) 		5 / 9 LEU A   2
PHE A   5
ILE A   9
GLY A  29
HIS A  47
 None
 0.37A 3oshA-1vapA:
18.2		 3oshA-1vapA:
40.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_B_DM5B602_1
(SERUM ALBUMIN)		 1vap PHOSPHOLIPASE A2
(Agkistrodon
piscivorus) 		5 / 9 VAL A  46
ALA A  92
PHE A  96
TYR A 103
TYR A  24
 None
 1.47A 4lb2B-1vapA:
1.4		 4lb2B-1vapA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 1vap PHOSPHOLIPASE A2
(Agkistrodon
piscivorus) 		5 / 12 GLY A  34
GLN A  33
ALA A  23
GLY A  25
TYR A 111
 None
 1.27A 4r29A-1vapA:
undetectable		 4r29A-1vapA:
15.35