SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vav'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		4 / 7 VAL A 134
LEU A 148
LEU A 169
LEU A 170
 None
 0.72A 1cqpA-1vavA:
undetectable
1cqpB-1vavA:
undetectable		 1cqpA-1vavA:
19.91
1cqpB-1vavA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 193
LEU A 218
THR A  10
ARG A  59
 None
 1.40A 1i2wA-1vavA:
undetectable		 1i2wA-1vavA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 169
VAL A 164
VAL A 134
VAL A 117
 None
 0.98A 1iwiA-1vavA:
undetectable		 1iwiA-1vavA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 197
VAL A 220
LEU A  83
LEU A 218
LEU A   9
 None
 0.99A 1mx1F-1vavA:
undetectable		 1mx1F-1vavA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		3 / 3 TRP A  44
VAL A  45
PRO A  46
 None
 0.78A 1rg1A-1vavA:
undetectable		 1rg1A-1vavA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		3 / 3 TRP A  44
VAL A  45
PRO A  46
 None
 0.77A 1rh0A-1vavA:
undetectable		 1rh0A-1vavA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 218
THR A  22
GLN A  26
HIS A 222
LEU A  83
 None
 1.14A 2jn3A-1vavA:
undetectable		 2jn3A-1vavA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		4 / 6 LEU A   9
LEU A  62
ILE A  11
ARG A  59
 None
 0.92A 2rlfC-1vavA:
undetectable
2rlfD-1vavA:
undetectable		 2rlfC-1vavA:
13.16
2rlfD-1vavA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		5 / 11 SER A 171
SER A 173
TYR A 160
GLY A 163
PHE A 194
 None
 1.41A 2xh9A-1vavA:
undetectable		 2xh9A-1vavA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 169
VAL A 164
VAL A 134
VAL A 117
 None
 0.93A 2z97A-1vavA:
undetectable		 2z97A-1vavA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T8N_D_EDTD135_0
(STEROID
DELTA-ISOMERASE)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 210
PRO A  93
GLY A  49
PRO A  58
ASP A 202
 None
 1.01A 3t8nD-1vavA:
0.0
3t8nF-1vavA:
undetectable		 3t8nD-1vavA:
19.48
3t8nF-1vavA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 169
VAL A 164
VAL A 134
VAL A 117
 None
 1.01A 4l4bA-1vavA:
undetectable		 4l4bA-1vavA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		3 / 3 GLU A  90
ARG A  88
GLN A  35
 None
 0.83A 4rtbA-1vavA:
undetectable		 4rtbA-1vavA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 169
VAL A 164
GLY A 163
VAL A 134
VAL A 117
 None
 1.32A 5cp4A-1vavA:
undetectable		 5cp4A-1vavA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 169
VAL A 164
VAL A 134
VAL A 117
 None
 1.01A 6cp4A-1vavA:
undetectable		 6cp4A-1vavA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 218
SER A 216
PHE A 215
 None
 0.56A 6fgcA-1vavA:
undetectable		 6fgcA-1vavA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1vav ALGINATE LYASE
PA1167
(Pseudomonas
aeruginosa) 		4 / 7 HIS A 222
ARG A  63
HIS A 104
GLU A  64
 None
 1.42A 6mn4F-1vavA:
0.0		 6mn4F-1vavA:
21.85