SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vb3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_2_T442129_1
(TRANSTHYRETIN)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 5 LYS A 383
LEU A 165
GLU A 387
ALA A 380
 None
 1.13A 1eta2-1vb3A:
undetectable		 1eta2-1vb3A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 184
SER A 210
ILE A 129
GLY A 138
ILE A 155
 None
 1.05A 1q8jB-1vb3A:
undetectable		 1q8jB-1vb3A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 6 LEU A 104
PHE A  99
ALA A 377
LEU A 400
 None
 1.01A 1ukbA-1vb3A:
2.3		 1ukbA-1vb3A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 5 ALA A 259
TYR A 225
ILE A 223
ASP A 252
 None
None
None
SO4  A 501 (-4.9A)
 1.23A 1upfA-1vb3A:
2.4		 1upfA-1vb3A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 5 ALA A 259
TYR A 225
ILE A 223
ASP A 252
 None
None
None
SO4  A 501 (-4.9A)
 1.16A 1upfC-1vb3A:
undetectable		 1upfC-1vb3A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_A_SAMA501_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 256
SER A 261
ALA A 255
ASP A 252
TYR A 225
 None
None
None
SO4  A 501 (-4.9A)
None
 1.46A 2avdA-1vb3A:
3.1		 2avdA-1vb3A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_A_SAMA501_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 256
SER A 261
VAL A 245
ALA A 255
TYR A 225
 None
 1.35A 2avdA-1vb3A:
3.1		 2avdA-1vb3A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 4 ASP A 136
ASP A 252
ASP A 108
GLY A 375
 KPA  A 500 (-4.7A)
SO4  A 501 (-4.9A)
None
None
 1.39A 2igtC-1vb3A:
2.2		 2igtC-1vb3A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 9 LEU A 394
PRO A 397
LEU A 400
LEU A 104
ALA A 377
 None
 1.16A 2vcvE-1vb3A:
undetectable		 2vcvE-1vb3A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 6 HIS A 284
GLN A 364
ALA A 330
THR A 273
 None
 1.08A 2xfhA-1vb3A:
undetectable		 2xfhA-1vb3A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 7 VAL A 312
ASN A 249
GLY A 248
VAL A 279
 None
KPA  A 500 ( 4.1A)
SO4  A 501 (-3.7A)
None
 0.81A 2y05A-1vb3A:
2.2
2y05B-1vb3A:
2.3		 2y05A-1vb3A:
22.71
2y05B-1vb3A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 PRO A  36
MET A   1
ILE A  63
LEU A 219
ILE A 216
 None
 1.01A 3a50D-1vb3A:
undetectable		 3a50D-1vb3A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A  94
LEU A  96
PRO A 234
ASN A  88
ALA A  87
 None
 1.04A 3av6A-1vb3A:
2.1		 3av6A-1vb3A:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 8 PHE A 106
THR A 137
ALA A 377
ALA A 105
 None
KPA  A 500 (-2.9A)
None
None
 0.84A 3ax9B-1vb3A:
undetectable		 3ax9B-1vb3A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		3 / 3 GLU A  97
VAL A  86
CYH A  95
 None
 1.00A 3fbxA-1vb3A:
undetectable		 3fbxA-1vb3A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 THR A 335
THR A 336
THR A 339
GLU A 342
LEU A 297
 None
 0.76A 3gwxB-1vb3A:
undetectable		 3gwxB-1vb3A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_A_ADNA439_1
(ADENOSYLHOMOCYSTEINA
SE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 10 LEU A  59
GLN A 116
HIS A 120
MET A 117
PHE A 113
 None
 1.39A 3h9uA-1vb3A:
2.0		 3h9uA-1vb3A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 10 LEU A  59
GLN A 116
HIS A 120
MET A 117
PHE A 113
 None
 1.42A 3h9uC-1vb3A:
undetectable		 3h9uC-1vb3A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 10 LEU A  59
GLN A 116
HIS A 120
MET A 117
PHE A 113
 None
 1.42A 3h9uD-1vb3A:
2.0		 3h9uD-1vb3A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 9 LEU A 409
THR A 179
HIS A 411
GLU A 178
HIS A 427
 None
 1.30A 3hy7B-1vb3A:
undetectable		 3hy7B-1vb3A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 6 SER A 134
GLN A 166
PHE A 382
HIS A 353
 KPA  A 500 (-3.1A)
None
None
None
 1.37A 3lskB-1vb3A:
0.0		 3lskB-1vb3A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 6 SER A 134
GLN A 166
PHE A 382
HIS A 353
 KPA  A 500 (-3.1A)
None
None
None
 1.33A 3lskD-1vb3A:
0.0		 3lskD-1vb3A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 6 PHE A 106
THR A 137
ALA A 377
ALA A 105
 None
KPA  A 500 (-2.9A)
None
None
 0.85A 3ns1C-1vb3A:
undetectable		 3ns1C-1vb3A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 8 PHE A 106
THR A 137
ALA A 377
ALA A 105
 None
KPA  A 500 (-2.9A)
None
None
 0.85A 3ns1L-1vb3A:
undetectable		 3ns1L-1vb3A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 ASN A 366
GLY A 371
PRO A 367
GLY A 368
CYH A  95
 None
 1.46A 3r24A-1vb3A:
undetectable		 3r24A-1vb3A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 256
ALA A 255
SER A  55
PHE A  38
GLU A  37
 None
 1.11A 3s8pA-1vb3A:
undetectable		 3s8pA-1vb3A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 256
ALA A 255
SER A  55
PHE A  38
GLU A  37
 None
 1.12A 3s8pB-1vb3A:
0.4		 3s8pB-1vb3A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_2
(ADENOSINE KINASE,
PUTATIVE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 5 ALA A  18
MET A 114
PHE A  15
ASN A 209
 None
 1.48A 3uq6A-1vb3A:
undetectable		 3uq6A-1vb3A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 PRO A  36
MET A   1
ILE A  63
ILE A 216
ILE A  58
 None
 1.00A 3vrmA-1vb3A:
undetectable		 3vrmA-1vb3A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 256
ALA A 255
SER A  55
PHE A  38
GLU A  37
 None
 1.16A 4bupB-1vb3A:
0.1		 4bupB-1vb3A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 LEU A 394
PHE A 382
VAL A 386
GLU A  97
HIS A 100
 None
 1.25A 4hvcB-1vb3A:
undetectable		 4hvcB-1vb3A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 11 SER A 134
GLY A 135
ALA A 105
ILE A  58
LEU A 262
 KPA  A 500 (-3.1A)
KPA  A 500 ( 4.2A)
None
None
None
 1.00A 4kt0A-1vb3A:
undetectable
4kt0J-1vb3A:
undetectable		 4kt0A-1vb3A:
20.26
4kt0J-1vb3A:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		3 / 3 HIS A 411
VAL A 193
LEU A 420
 None
 0.68A 4m2vA-1vb3A:
undetectable		 4m2vA-1vb3A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 THR A 137
GLY A 135
HIS A 353
ILE A 155
SER A 210
 KPA  A 500 (-2.9A)
KPA  A 500 ( 4.2A)
None
None
None
 1.27A 4pooB-1vb3A:
2.2		 4pooB-1vb3A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 5 TYR A 226
GLY A 251
TYR A 225
GLY A 110
 None
SO4  A 501 (-3.6A)
None
None
 1.07A 5ayfA-1vb3A:
undetectable		 5ayfA-1vb3A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 375
ALA A 272
ILE A 270
LEU A 361
ALA A  87
 None
 1.24A 5bw4B-1vb3A:
undetectable		 5bw4B-1vb3A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 256
ALA A 255
SER A  55
PHE A  38
GLU A  37
 None
 1.18A 5cprB-1vb3A:
undetectable		 5cprB-1vb3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 4 VAL A 242
GLU A 369
GLY A 371
LEU A 361
 None
 1.40A 5g5gC-1vb3A:
undetectable		 5g5gC-1vb3A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 LEU A 372
THR A 237
GLY A  94
VAL A  89
LEU A 233
 None
 1.24A 5jo9A-1vb3A:
3.4		 5jo9A-1vb3A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 GLY A 111
MET A 114
LEU A 118
ASN A 215
ASN A 209
 None
 1.42A 5kbwA-1vb3A:
undetectable		 5kbwA-1vb3A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 4 GLN A 240
THR A 237
LEU A 361
LEU A 365
 None
 1.23A 5m5kB-1vb3A:
2.3		 5m5kB-1vb3A:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 7 SER A 261
LEU A 258
LEU A 315
PRO A  36
 None
 1.01A 5u4sA-1vb3A:
undetectable		 5u4sA-1vb3A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		3 / 3 LEU A 104
ALA A 105
LEU A 400
 None
 0.52A 5uunB-1vb3A:
undetectable		 5uunB-1vb3A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		5 / 12 LEU A 394
PHE A 382
VAL A 386
GLU A  97
HIS A 100
 None
 1.31A 5xiqB-1vb3A:
undetectable		 5xiqB-1vb3A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		4 / 6 ALA A 377
SER A 350
THR A 336
ASN A 274
 None
 0.81A 6f88B-1vb3A:
undetectable		 6f88B-1vb3A:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		3 / 3 LEU A 264
LEU A  47
ARG A 238
 None
 0.64A 6fgcA-1vb3A:
undetectable		 6fgcA-1vb3A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 1vb3 THREONINE SYNTHASE
(Escherichia
coli) 		3 / 3 LEU A 264
LEU A  47
ARG A 238
 None
 0.66A 6fgdA-1vb3A:
undetectable		 6fgdA-1vb3A:
23.37