SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vb4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 8 SER A  80
GLY A 175
THR A 126
ILE A 128
 None
 0.81A 1c9sI-1vb4A:
undetectable
1c9sJ-1vb4A:
undetectable		 1c9sI-1vb4A:
14.55
1c9sJ-1vb4A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 8 GLY A 175
THR A 126
ILE A 128
SER A  80
 None
 0.79A 1c9sU-1vb4A:
undetectable
1c9sV-1vb4A:
undetectable		 1c9sU-1vb4A:
14.55
1c9sV-1vb4A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 8 SER A  80
GLY A 175
THR A 126
ILE A 128
 None
 0.80A 1gtnA-1vb4A:
undetectable
1gtnB-1vb4A:
undetectable		 1gtnA-1vb4A:
14.55
1gtnB-1vb4A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 7 SER A  80
GLY A 175
THR A 126
ILE A 128
 None
 0.81A 1gtnC-1vb4A:
undetectable
1gtnD-1vb4A:
undetectable		 1gtnC-1vb4A:
14.55
1gtnD-1vb4A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 6 SER A  80
GLY A 175
THR A 126
ILE A 128
 None
 0.80A 1gtnD-1vb4A:
undetectable
1gtnE-1vb4A:
undetectable		 1gtnD-1vb4A:
14.55
1gtnE-1vb4A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 8 SER A  80
GLY A 175
THR A 126
ILE A 128
 None
 0.81A 1gtnE-1vb4A:
undetectable
1gtnF-1vb4A:
undetectable		 1gtnE-1vb4A:
14.55
1gtnF-1vb4A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 7 SER A  80
GLY A 175
THR A 126
ILE A 128
 None
 0.81A 1gtnF-1vb4A:
undetectable
1gtnG-1vb4A:
undetectable		 1gtnF-1vb4A:
14.55
1gtnG-1vb4A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 7 SER A  80
GLY A 175
THR A 126
ILE A 128
 None
 0.81A 1gtnJ-1vb4A:
undetectable
1gtnK-1vb4A:
undetectable		 1gtnJ-1vb4A:
14.55
1gtnK-1vb4A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 8 GLY A 175
THR A 126
ILE A 128
SER A  80
 None
 0.82A 1gtnP-1vb4A:
0.4
1gtnQ-1vb4A:
undetectable		 1gtnP-1vb4A:
14.55
1gtnQ-1vb4A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 8 GLY A 175
THR A 126
ILE A 128
SER A  80
 None
 0.81A 1utdI-1vb4A:
undetectable
1utdJ-1vb4A:
undetectable		 1utdI-1vb4A:
14.55
1utdJ-1vb4A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 8 GLY A 175
THR A 126
ILE A 128
SER A  80
 None
 0.80A 1utdJ-1vb4A:
0.5
1utdK-1vb4A:
undetectable		 1utdJ-1vb4A:
14.55
1utdK-1vb4A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 8 GLY A 218
THR A 215
ALA A 216
VAL A 228
 None
 0.87A 2a1hA-1vb4A:
undetectable
2a1hB-1vb4A:
undetectable		 2a1hA-1vb4A:
20.65
2a1hB-1vb4A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 8 VAL A 228
GLY A 218
THR A 215
ALA A 216
 None
 0.85A 2a1hA-1vb4A:
undetectable
2a1hB-1vb4A:
undetectable		 2a1hA-1vb4A:
20.65
2a1hB-1vb4A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		5 / 12 GLY A 142
TYR A 145
LEU A 200
VAL A 197
SER A 122
 None
 1.37A 2vqyA-1vb4A:
undetectable		 2vqyA-1vb4A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		5 / 12 VAL A 155
LEU A 158
SER A 159
GLY A 167
SER A 138
 None
 1.01A 4coxC-1vb4A:
undetectable		 4coxC-1vb4A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 6 ASP A 196
ARG A 162
GLY A 142
VAL A 165
 None
 0.87A 4oltA-1vb4A:
undetectable		 4oltA-1vb4A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 6 ASP A 196
ARG A 162
GLY A 142
VAL A 165
 None
 0.87A 4oltB-1vb4A:
undetectable		 4oltB-1vb4A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		5 / 12 VAL A 155
LEU A 158
SER A 159
GLY A 167
SER A 138
 None
 1.03A 4otyA-1vb4A:
undetectable		 4otyA-1vb4A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		5 / 12 VAL A 155
LEU A 158
SER A 159
GLY A 167
SER A 138
 None
 1.05A 4otyB-1vb4A:
undetectable		 4otyB-1vb4A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		4 / 8 LEU A 227
ASP A 212
ALA A 216
VAL A 219
 None
 0.80A 4zbqA-1vb4A:
undetectable		 4zbqA-1vb4A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		5 / 9 ILE A 256
TYR A 254
LEU A  77
GLU A  81
GLY A 110
 None
 1.35A 5ifuB-1vb4A:
undetectable		 5ifuB-1vb4A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1vb4 COAT PROTEIN
(Sesbania
mosaic
virus) 		3 / 3 VAL A 197
SER A 122
TRP A 120
 None
 1.02A 5jwaA-1vb4A:
undetectable		 5jwaA-1vb4A:
16.99