SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vbc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 6 LEU 3 100
ILE 3  53
ASP 3  92
PRO 3  89
 None
 0.99A 1ditH-1vbc3:
undetectable
1ditP-1vbc3:
undetectable		 1ditH-1vbc3:
23.21
1ditP-1vbc3:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 7 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.90A 1v55C-1vbc3:
undetectable
1v55N-1vbc3:
undetectable
1v55P-1vbc3:
undetectable		 1v55C-1vbc3:
22.66
1v55N-1vbc3:
18.30
1v55P-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.86A 2y69C-1vbc3:
undetectable
2y69N-1vbc3:
undetectable
2y69P-1vbc3:
undetectable		 2y69C-1vbc3:
22.66
2y69N-1vbc3:
18.30
2y69P-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 HIS 3  97
ASP 3 227
THR 3 228
LEU 3 225
 None
 0.97A 3ablA-1vbc3:
undetectable
3ablC-1vbc3:
undetectable
3ablP-1vbc3:
undetectable		 3ablA-1vbc3:
18.30
3ablC-1vbc3:
22.66
3ablP-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.87A 3ablC-1vbc3:
undetectable
3ablN-1vbc3:
undetectable
3ablP-1vbc3:
undetectable		 3ablC-1vbc3:
22.66
3ablN-1vbc3:
18.30
3ablP-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 6 ILE 3  82
ARG 3 197
THR 3 127
LEU 3 158
 None
 0.92A 3ag1N-1vbc3:
undetectable
3ag1W-1vbc3:
undetectable		 3ag1N-1vbc3:
18.30
3ag1W-1vbc3:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.92A 3asnC-1vbc3:
undetectable
3asnN-1vbc3:
undetectable
3asnP-1vbc3:
undetectable		 3asnC-1vbc3:
22.66
3asnN-1vbc3:
18.30
3asnP-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.92A 3asoC-1vbc3:
undetectable
3asoN-1vbc3:
undetectable
3asoP-1vbc3:
undetectable		 3asoC-1vbc3:
22.66
3asoN-1vbc3:
18.30
3asoP-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.84A 3x2qC-1vbc3:
undetectable
3x2qN-1vbc3:
undetectable
3x2qP-1vbc3:
undetectable		 3x2qC-1vbc3:
22.66
3x2qN-1vbc3:
18.30
3x2qP-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 5 ILE 3  49
HIS 3 230
TYR 3 107
VAL 3 222
 None
 1.29A 4s0vA-1vbc3:
undetectable		 4s0vA-1vbc3:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 HIS 3  97
ASP 3 227
THR 3 228
LEU 3 225
 None
 0.97A 5b1bA-1vbc3:
undetectable
5b1bC-1vbc3:
undetectable
5b1bP-1vbc3:
undetectable		 5b1bA-1vbc3:
18.30
5b1bC-1vbc3:
22.66
5b1bP-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 HIS 3  97
ASP 3 227
THR 3 228
LEU 3 225
 None
 0.93A 5w97A-1vbc3:
undetectable
5w97C-1vbc3:
undetectable
5w97c-1vbc3:
undetectable		 5w97A-1vbc3:
18.30
5w97C-1vbc3:
22.66
5w97c-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 7 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.95A 5w97C-1vbc3:
undetectable
5w97a-1vbc3:
undetectable
5w97c-1vbc3:
undetectable		 5w97C-1vbc3:
22.66
5w97a-1vbc3:
18.30
5w97c-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 7 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.95A 5wauC-1vbc3:
undetectable
5waua-1vbc3:
undetectable
5wauc-1vbc3:
undetectable		 5wauC-1vbc3:
22.66
5waua-1vbc3:
18.30
5wauc-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 HIS 3  97
ASP 3 227
THR 3 228
LEU 3 225
 None
 1.01A 5x19A-1vbc3:
undetectable
5x19C-1vbc3:
undetectable
5x19P-1vbc3:
undetectable		 5x19A-1vbc3:
18.30
5x19C-1vbc3:
22.66
5x19P-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 7 HIS 3  97
ASP 3 227
THR 3 228
LEU 3 225
 None
 1.02A 5x1bA-1vbc3:
undetectable
5x1bC-1vbc3:
undetectable
5x1bP-1vbc3:
undetectable		 5x1bA-1vbc3:
18.30
5x1bC-1vbc3:
22.66
5x1bP-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 7 HIS 3  97
ASP 3 227
THR 3 228
LEU 3 225
 None
 0.95A 5x1fA-1vbc3:
undetectable
5x1fC-1vbc3:
undetectable
5x1fP-1vbc3:
undetectable		 5x1fA-1vbc3:
18.30
5x1fC-1vbc3:
22.66
5x1fP-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 THR 3 229
THR 3 228
TYR 3 106
PRO 3  93
 None
 1.02A 5x2sI-1vbc3:
undetectable
5x2sJ-1vbc3:
undetectable
5x2sK-1vbc3:
undetectable		 5x2sI-1vbc3:
19.83
5x2sJ-1vbc3:
20.70
5x2sK-1vbc3:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.91A 5xdqC-1vbc3:
undetectable
5xdqN-1vbc3:
undetectable
5xdqP-1vbc3:
undetectable		 5xdqC-1vbc3:
22.66
5xdqN-1vbc3:
18.30
5xdqP-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.91A 5xdxC-1vbc3:
undetectable
5xdxN-1vbc3:
undetectable
5xdxP-1vbc3:
undetectable		 5xdxC-1vbc3:
23.16
5xdxN-1vbc3:
18.30
5xdxP-1vbc3:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 7 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.93A 5z84C-1vbc3:
undetectable
5z84N-1vbc3:
undetectable
5z84P-1vbc3:
undetectable		 5z84C-1vbc3:
22.66
5z84N-1vbc3:
18.30
5z84P-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.92A 5z86C-1vbc3:
undetectable
5z86N-1vbc3:
undetectable
5z86P-1vbc3:
undetectable		 5z86C-1vbc3:
22.66
5z86N-1vbc3:
18.30
5z86P-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.91A 5zcoC-1vbc3:
undetectable
5zcoN-1vbc3:
undetectable
5zcoP-1vbc3:
undetectable		 5zcoC-1vbc3:
22.66
5zcoN-1vbc3:
18.30
5zcoP-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 6 ILE 3  82
ARG 3 197
THR 3 127
LEU 3 158
 None
 1.04A 5zcoN-1vbc3:
undetectable
5zcoW-1vbc3:
undetectable		 5zcoN-1vbc3:
18.30
5zcoW-1vbc3:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.93A 5zcpC-1vbc3:
undetectable
5zcpN-1vbc3:
undetectable
5zcpP-1vbc3:
undetectable		 5zcpC-1vbc3:
22.66
5zcpN-1vbc3:
18.30
5zcpP-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 8 LEU 3 225
HIS 3  97
ASP 3 227
THR 3 228
 None
 0.97A 6nknC-1vbc3:
undetectable
6nknN-1vbc3:
undetectable
6nknP-1vbc3:
undetectable		 6nknC-1vbc3:
22.66
6nknN-1vbc3:
18.30
6nknP-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 7 HIS 3  97
ASP 3 227
THR 3 228
LEU 3 225
 None
 1.00A 6nmfA-1vbc3:
undetectable
6nmfC-1vbc3:
undetectable
6nmfP-1vbc3:
undetectable		 6nmfA-1vbc3:
18.30
6nmfC-1vbc3:
22.66
6nmfP-1vbc3:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1vbc POLIOVIRUS TYPE 3
(Enterovirus
C) 		4 / 5 ILE 3  82
ARG 3 197
THR 3 127
LEU 3 158
 None
 0.93A 6nmpN-1vbc3:
undetectable
6nmpW-1vbc3:
0.0		 6nmpN-1vbc3:
18.30
6nmpW-1vbc3:
13.79