SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vbk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 1vbk HYPOTHETICAL PROTEIN
PH1313
(Pyrococcus
horikoshii) 		5 / 12 VAL A 247
ILE A 183
ILE A 260
ALA A 194
PHE A 282
 None
 1.09A 2gj5A-1vbkA:
undetectable		 2gj5A-1vbkA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 1vbk HYPOTHETICAL PROTEIN
PH1313
(Pyrococcus
horikoshii) 		3 / 3 LYS A 212
ARG A 246
VAL A 240
 None
 1.03A 2r2vC-1vbkA:
0.0
2r2vD-1vbkA:
0.0		 2r2vC-1vbkA:
7.89
2r2vD-1vbkA:
7.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 1vbk HYPOTHETICAL PROTEIN
PH1313
(Pyrococcus
horikoshii) 		5 / 12 ALA A 241
PHE A 244
VAL A 259
GLY A 258
PRO A 283
 None
 1.06A 2ve3B-1vbkA:
undetectable		 2ve3B-1vbkA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 1vbk HYPOTHETICAL PROTEIN
PH1313
(Pyrococcus
horikoshii) 		4 / 5 ILE A  87
TYR A 134
MET A  94
ILE A 152
 None
 1.23A 3eteB-1vbkA:
2.5
3eteC-1vbkA:
2.8		 3eteB-1vbkA:
22.16
3eteC-1vbkA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1vbk HYPOTHETICAL PROTEIN
PH1313
(Pyrococcus
horikoshii) 		3 / 3 ASP A 253
ARG A 246
LYS A 249
 None
 1.01A 3wipG-1vbkA:
undetectable		 3wipG-1vbkA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1vbk HYPOTHETICAL PROTEIN
PH1313
(Pyrococcus
horikoshii) 		4 / 4 THR A  36
ARG A  31
GLU A  32
VAL A  35
 None
 1.38A 4odoC-1vbkA:
0.0		 4odoC-1vbkA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1vbk HYPOTHETICAL PROTEIN
PH1313
(Pyrococcus
horikoshii) 		4 / 7 GLU A  43
ARG A  50
ILE A  51
MET A  27
 None
 0.97A 4xumA-1vbkA:
undetectable		 4xumA-1vbkA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 1vbk HYPOTHETICAL PROTEIN
PH1313
(Pyrococcus
horikoshii) 		5 / 7 ILE A 154
MET A  94
ALA A  91
ASN A  88
ILE A  87
 None
 1.48A 4y03A-1vbkA:
undetectable		 4y03A-1vbkA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1vbk HYPOTHETICAL PROTEIN
PH1313
(Pyrococcus
horikoshii) 		4 / 5 PRO A 289
GLY A 262
TYR A 288
VAL A 259
 None
 1.19A 5x80C-1vbkA:
undetectable
5x80D-1vbkA:
undetectable		 5x80C-1vbkA:
19.03
5x80D-1vbkA:
19.03