SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vbm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 6 TRP A 100
GLY A  80
ASN A  92
PRO A  82
 None
 1.19A 1dedA-1vbmA:
undetectable		 1dedA-1vbmA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_A_CAMA503_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 9 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.37A 1dz8A-1vbmA:
undetectable		 1dz8A-1vbmA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_B_CAMB502_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 9 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.41A 1dz8B-1vbmA:
undetectable		 1dz8B-1vbmA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 9 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.34A 1gebA-1vbmA:
undetectable		 1gebA-1vbmA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 11 PHE A 114
ALA A 121
TYR A  37
LEU A 194
GLN A 195
 None
None
YSA  A3001 (-4.7A)
None
YSA  A3001 (-4.4A)
 1.23A 1hbpA-1vbmA:
undetectable		 1hbpA-1vbmA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 HIS A  66
LEU A  29
ALA A  26
LEU A  25
 None
 0.81A 1hwiD-1vbmA:
undetectable		 1hwiD-1vbmA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 8 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.38A 1iwiA-1vbmA:
undetectable		 1iwiA-1vbmA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWJ_A_CAMA418_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 9 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.38A 1iwjA-1vbmA:
0.0		 1iwjA-1vbmA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		6 / 11 GLY A  39
HIS A  48
HIS A  51
GLY A 198
ASP A 200
GLN A 201
 YSA  A3001 (-3.1A)
SO4  A2003 (-3.9A)
YSA  A3001 ( 3.8A)
YSA  A3001 (-3.0A)
YSA  A3001 (-3.2A)
YSA  A3001 (-3.5A)
 0.71A 1jzsA-1vbmA:
undetectable		 1jzsA-1vbmA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		6 / 11 GLY A  39
HIS A  51
GLY A 198
ASP A 200
GLN A 201
ILE A 228
 YSA  A3001 (-3.1A)
YSA  A3001 ( 3.8A)
YSA  A3001 (-3.0A)
YSA  A3001 (-3.2A)
YSA  A3001 (-3.5A)
YSA  A3001 (-4.1A)
 0.78A 1jzsA-1vbmA:
undetectable		 1jzsA-1vbmA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 10 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.36A 1o76A-1vbmA:
undetectable		 1o76A-1vbmA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 11 HIS A  48
GLY A  50
HIS A  51
GLY A 198
ASP A 200
 SO4  A2003 (-3.9A)
YSA  A3001 (-3.3A)
YSA  A3001 ( 3.8A)
YSA  A3001 (-3.0A)
YSA  A3001 (-3.2A)
 0.36A 1pg2A-1vbmA:
9.3		 1pg2A-1vbmA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 GLY A  50
HIS A  51
GLY A 198
ASP A 200
GLN A 201
 YSA  A3001 (-3.3A)
YSA  A3001 ( 3.8A)
YSA  A3001 (-3.0A)
YSA  A3001 (-3.2A)
YSA  A3001 (-3.5A)
 0.45A 1qu2A-1vbmA:
6.8		 1qu2A-1vbmA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 8 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.33A 1t86A-1vbmA:
undetectable		 1t86A-1vbmA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 9 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.32A 1t86B-1vbmA:
0.0		 1t86B-1vbmA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.37A 1t87A-1vbmA:
undetectable		 1t87A-1vbmA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.37A 1t87B-1vbmA:
undetectable		 1t87B-1vbmA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.19A 1uyuA-1vbmA:
undetectable		 1uyuA-1vbmA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.33A 1yrcA-1vbmA:
0.0		 1yrcA-1vbmA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.37A 1yrdA-1vbmA:
0.0		 1yrdA-1vbmA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 9 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.33A 2a1oB-1vbmA:
undetectable		 2a1oB-1vbmA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 LEU A 194
LEU A  36
ALA A  35
LEU A  29
THR A 212
 None
 1.25A 2aa6A-1vbmA:
undetectable		 2aa6A-1vbmA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA601_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 TYR A  37
GLY A  39
THR A  76
GLN A 179
GLN A 201
 YSA  A3001 (-4.7A)
YSA  A3001 (-3.1A)
YSA  A3001 (-3.7A)
YSA  A3001 (-3.5A)
YSA  A3001 (-3.5A)
 0.89A 2azxA-1vbmA:
20.5		 2azxA-1vbmA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 ASP A  41
TYR A 175
LEU A  71
LEU A 186
 YSA  A3001 (-3.9A)
YSA  A3001 (-4.3A)
None
None
 0.97A 2bfpC-1vbmA:
5.4		 2bfpC-1vbmA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 7 ASP A  41
GLY A  73
GLY A  74
ASN A 126
 YSA  A3001 (-3.9A)
YSA  A3001 ( 4.9A)
None
YSA  A3001 ( 4.9A)
 0.76A 2c49B-1vbmA:
2.2		 2c49B-1vbmA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 6 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.31A 2feuA-1vbmA:
0.0		 2feuA-1vbmA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.30A 2feuB-1vbmA:
0.0		 2feuB-1vbmA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 9 ILE A 196
GLY A 197
GLY A 198
LEU A  56
CYH A  57
 None
YSA  A3001 (-3.6A)
YSA  A3001 (-3.0A)
None
None
 1.13A 2qmmA-1vbmA:
undetectable		 2qmmA-1vbmA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 11 HIS A  48
GLY A  50
HIS A  51
GLY A 198
ASP A 200
 SO4  A2003 (-3.9A)
YSA  A3001 (-3.3A)
YSA  A3001 ( 3.8A)
YSA  A3001 (-3.0A)
YSA  A3001 (-3.2A)
 0.46A 2x1lA-1vbmA:
8.2		 2x1lA-1vbmA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 HIS A  48
GLY A  50
HIS A  51
GLY A 198
ASP A 200
 SO4  A2003 (-3.9A)
YSA  A3001 (-3.3A)
YSA  A3001 ( 3.8A)
YSA  A3001 (-3.0A)
YSA  A3001 (-3.2A)
 0.45A 2x1lB-1vbmA:
7.5		 2x1lB-1vbmA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 11 HIS A  48
GLY A  50
HIS A  51
GLY A 198
ASP A 200
 SO4  A2003 (-3.9A)
YSA  A3001 (-3.3A)
YSA  A3001 ( 3.8A)
YSA  A3001 (-3.0A)
YSA  A3001 (-3.2A)
 0.49A 2x1lC-1vbmA:
7.6		 2x1lC-1vbmA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 6 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.32A 2zuhA-1vbmA:
undetectable		 2zuhA-1vbmA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 6 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.39A 2zuiA-1vbmA:
0.0		 2zuiA-1vbmA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.35A 2zwtA-1vbmA:
0.0		 2zwtA-1vbmA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.35A 2zwuA-1vbmA:
0.0		 2zwuA-1vbmA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.30A 3fwfA-1vbmA:
0.0		 3fwfA-1vbmA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.29A 3fwfB-1vbmA:
0.0		 3fwfB-1vbmA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.37A 3fwiA-1vbmA:
undetectable		 3fwiA-1vbmA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.32A 3fwjA-1vbmA:
0.0		 3fwjA-1vbmA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECLB600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 LEU A 178
GLY A 203
ALA A 156
ILE A 168
 None
 0.79A 3jusB-1vbmA:
undetectable		 3jusB-1vbmA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.28A 3l63A-1vbmA:
0.0		 3l63A-1vbmA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_A_CYZA266_2
(GLUTAMATE RECEPTOR 2)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 5 ILE A 196
PRO A  54
SER A 199
GLY A 197
 None
YSA  A3001 (-4.1A)
None
YSA  A3001 (-3.6A)
 1.04A 3tkdB-1vbmA:
undetectable		 3tkdB-1vbmA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKD_B_CYZB267_1
(GLUTAMATE RECEPTOR 2)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 5 ILE A 196
PRO A  54
SER A 199
GLY A 197
 None
YSA  A3001 (-4.1A)
None
YSA  A3001 (-3.6A)
 1.04A 3tkdA-1vbmA:
undetectable		 3tkdA-1vbmA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.31A 3wrhA-1vbmA:
0.0		 3wrhA-1vbmA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.34A 3wrjA-1vbmA:
0.0		 3wrjA-1vbmA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.31A 3wrlA-1vbmA:
0.0		 3wrlA-1vbmA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.31A 3wrlE-1vbmA:
0.0		 3wrlE-1vbmA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.32A 3wrmA-1vbmA:
0.0		 3wrmA-1vbmA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 7 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.35A 3wrmF-1vbmA:
0.0		 3wrmF-1vbmA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 ASN A 126
TRP A 129
ASP A  41
 YSA  A3001 ( 4.9A)
None
YSA  A3001 (-3.9A)
 1.01A 4a7tA-1vbmA:
undetectable
4a7tF-1vbmA:
undetectable		 4a7tA-1vbmA:
18.87
4a7tF-1vbmA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 LEU A  55
LEU A  52
LEU A  49
HIS A 312
 None
 0.85A 4klaA-1vbmA:
undetectable		 4klaA-1vbmA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 8 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.35A 4l4aA-1vbmA:
0.0		 4l4aA-1vbmA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.17A 4l4eA-1vbmA:
0.0		 4l4eA-1vbmA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 HIS A  48
GLY A  50
HIS A  51
GLY A 198
ASP A 200
 SO4  A2003 (-3.9A)
YSA  A3001 (-3.3A)
YSA  A3001 ( 3.8A)
YSA  A3001 (-3.0A)
YSA  A3001 (-3.2A)
 1.00A 5hg0B-1vbmA:
7.8		 5hg0B-1vbmA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 LEU A 223
PHE A  61
LEU A  29
ILE A  34
 None
 0.92A 5mzjA-1vbmA:
0.3		 5mzjA-1vbmA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 6 ILE A 104
ILE A  79
LEU A  78
PHE A 138
 None
 0.97A 5vkqB-1vbmA:
undetectable
5vkqC-1vbmA:
undetectable		 5vkqB-1vbmA:
10.93
5vkqC-1vbmA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1vbm TYROSYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 6 ILE A 104
ILE A  79
LEU A  78
PHE A 138
 None
 0.95A 5vkqC-1vbmA:
undetectable
5vkqD-1vbmA:
undetectable		 5vkqC-1vbmA:
10.93
5vkqD-1vbmA:
10.93