SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 1vc9 NDX1
(Thermus
thermophilus) 		4 / 7 ALA A  43
GLU A  46
VAL A   9
MET A  81
 None
MG  A2001 (-2.6A)
None
None
 0.88A 1hk2A-1vc9A:
undetectable		 1hk2A-1vc9A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 1vc9 NDX1
(Thermus
thermophilus) 		5 / 11 ALA A 120
VAL A   8
MET A  81
ARG A  82
ALA A  43
 None
 1.19A 1n4hA-1vc9A:
undetectable		 1n4hA-1vc9A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 1vc9 NDX1
(Thermus
thermophilus) 		3 / 3 ASP A 113
LEU A 116
HIS A  32
 ATP  A1001 ( 4.9A)
None
ATP  A1001 ( 4.2A)
 0.64A 1qknA-1vc9A:
undetectable		 1qknA-1vc9A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1vc9 NDX1
(Thermus
thermophilus) 		4 / 8 LEU A 108
LEU A 121
ALA A 120
PHE A  10
 None
 0.88A 2vcvF-1vc9A:
undetectable		 2vcvF-1vc9A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1vc9 NDX1
(Thermus
thermophilus) 		4 / 8 LEU A 108
LEU A 121
ALA A 120
PHE A  10
 None
 0.85A 2vcvP-1vc9A:
undetectable		 2vcvP-1vc9A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 1vc9 NDX1
(Thermus
thermophilus) 		5 / 7 LEU A 108
LEU A  18
PHE A  28
GLU A 118
PRO A 101
 None
 1.41A 2vq5B-1vc9A:
undetectable		 2vq5B-1vc9A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 1vc9 NDX1
(Thermus
thermophilus) 		3 / 3 ASN A  11
LEU A 121
PHE A  99
 None
 0.77A 4dajB-1vc9A:
undetectable		 4dajB-1vc9A:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1vc9 NDX1
(Thermus
thermophilus) 		3 / 3 ASN A  11
LEU A 121
PHE A  99
 None
 0.77A 5dsgA-1vc9A:
undetectable		 5dsgA-1vc9A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1vc9 NDX1
(Thermus
thermophilus) 		5 / 12 LEU A  58
ALA A 120
VAL A   9
GLY A  83
ALA A  55
 None
 1.09A 5jw1B-1vc9A:
undetectable		 5jw1B-1vc9A:
15.11