SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vct'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 1vct HYPOTHETICAL PROTEIN
PH0236
(Pyrococcus
horikoshii) 		3 / 3 GLU A  42
ALA A  44
SER A  35
 None
 0.62A 1errB-1vctA:
undetectable		 1errB-1vctA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 1vct HYPOTHETICAL PROTEIN
PH0236
(Pyrococcus
horikoshii) 		4 / 5 LEU A 142
ILE A 200
ILE A 192
ALA A 193
 None
 0.75A 2i2zA-1vctA:
undetectable		 2i2zA-1vctA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 1vct HYPOTHETICAL PROTEIN
PH0236
(Pyrococcus
horikoshii) 		3 / 3 GLU A 191
SER A 132
VAL A 133
 None
 0.71A 3eeoA-1vctA:
undetectable		 3eeoA-1vctA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1vct HYPOTHETICAL PROTEIN
PH0236
(Pyrococcus
horikoshii) 		5 / 12 VAL A 155
PRO A 165
GLY A 124
LEU A 189
ILE A 186
 None
 0.93A 3ku1H-1vctA:
undetectable		 3ku1H-1vctA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 1vct HYPOTHETICAL PROTEIN
PH0236
(Pyrococcus
horikoshii) 		5 / 12 GLY A 149
ASP A 143
ILE A 200
ILE A 126
ILE A 197
 None
 0.84A 5e5jB-1vctA:
undetectable		 5e5jB-1vctA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 1vct HYPOTHETICAL PROTEIN
PH0236
(Pyrococcus
horikoshii) 		4 / 8 GLY A 164
ARG A 180
ASP A  30
ASP A  23
 None
 0.83A 5vlmB-1vctA:
2.8		 5vlmB-1vctA:
20.72