SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vd2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 1vd2 PROTEIN KINASE C,
IOTA TYPE
(Homo
sapiens) 		3 / 3 GLU A  76
LYS A  60
VAL A  71
 None
 0.91A 1l2iA-1vd2A:
undetectable		 1l2iA-1vd2A:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1vd2 PROTEIN KINASE C,
IOTA TYPE
(Homo
sapiens) 		4 / 8 VAL A  45
MET A  48
TYR A  22
ILE A  94
 None
 0.89A 3remA-1vd2A:
undetectable		 3remA-1vd2A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1vd2 PROTEIN KINASE C,
IOTA TYPE
(Homo
sapiens) 		4 / 8 VAL A  45
MET A  48
TYR A  22
ILE A  94
 None
 0.89A 3remB-1vd2A:
undetectable		 3remB-1vd2A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 1vd2 PROTEIN KINASE C,
IOTA TYPE
(Homo
sapiens) 		4 / 7 VAL A  19
MET A  59
LEU A  77
ILE A  36
 None
 0.89A 3rfmA-1vd2A:
undetectable		 3rfmA-1vd2A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 1vd2 PROTEIN KINASE C,
IOTA TYPE
(Homo
sapiens) 		4 / 5 ASN A  43
VAL A  19
LEU A  92
SER A  37
 None
 1.31A 6a7pA-1vd2A:
undetectable		 6a7pA-1vd2A:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA607_0
(ALPHA-AMYLASE)		 1vd2 PROTEIN KINASE C,
IOTA TYPE
(Homo
sapiens) 		4 / 4 ARG A  46
SER A  50
ASP A  47
ASN A  53
 None
 1.34A 6ag0A-1vd2A:
undetectable		 6ag0A-1vd2A:
23.66