SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vdl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AJ6_A_NOVA1_1
(GYRASE)		 1vdl UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Mus
musculus) 		5 / 9 ASN A  65
ILE A  37
ALA A  40
ILE A  42
THR A  35
 None
 1.24A 1aj6A-1vdlA:
undetectable		 1aj6A-1vdlA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1vdl UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Mus
musculus) 		5 / 12 ILE A  42
ALA A  46
LEU A  28
LEU A  61
ALA A  57
 None
 0.98A 1fm9A-1vdlA:
undetectable		 1fm9A-1vdlA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1vdl UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Mus
musculus) 		5 / 12 ILE A  42
ALA A  46
LEU A  28
LEU A  61
ALA A  57
 None
 0.98A 1k74A-1vdlA:
undetectable		 1k74A-1vdlA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1vdl UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Mus
musculus) 		5 / 12 ILE A  42
ALA A  46
LEU A  28
LEU A  61
ALA A  57
 None
 0.92A 1xlsA-1vdlA:
undetectable		 1xlsA-1vdlA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1vdl UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Mus
musculus) 		5 / 12 ILE A  42
ALA A  46
LEU A  28
LEU A  61
ALA A  57
 None
 0.92A 1xlsB-1vdlA:
undetectable		 1xlsB-1vdlA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1vdl UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Mus
musculus) 		5 / 12 ILE A  42
ALA A  46
LEU A  28
LEU A  61
ALA A  57
 None
 0.93A 1xlsC-1vdlA:
undetectable		 1xlsC-1vdlA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1vdl UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Mus
musculus) 		5 / 12 ILE A  42
ALA A  46
LEU A  28
LEU A  61
ALA A  57
 None
 0.92A 1xlsD-1vdlA:
undetectable		 1xlsD-1vdlA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1vdl UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Mus
musculus) 		5 / 12 ILE A  42
ALA A  46
LEU A  28
LEU A  61
ALA A  57
 None
 0.93A 4k6iA-1vdlA:
undetectable		 4k6iA-1vdlA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1vdl UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 25
(Mus
musculus) 		5 / 12 ILE A  42
ALA A  46
LEU A  28
LEU A  61
ALA A  57
 None
 0.95A 5z12B-1vdlA:
undetectable		 5z12B-1vdlA:
17.86