SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ve0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAW_A_SUZA91_1
(SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-1)		 1ve0 HYPOTHETICAL PROTEIN
(ST2072)
(Sulfurisphaera
tokodaii) 		5 / 11 GLY A  94
ILE A  93
SER A  90
ILE A  89
VAL A  69
 None
 1.02A 2kawA-1ve0A:
undetectable		 2kawA-1ve0A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1ve0 HYPOTHETICAL PROTEIN
(ST2072)
(Sulfurisphaera
tokodaii) 		4 / 6 ILE A  93
ILE A 115
SER A  18
PHE A 119
 None
 0.93A 4m51A-1ve0A:
undetectable		 4m51A-1ve0A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 1ve0 HYPOTHETICAL PROTEIN
(ST2072)
(Sulfurisphaera
tokodaii) 		5 / 12 ASN A  63
ALA A  65
PHE A  16
GLY A  73
ASP A  72
 None
 1.23A 4n09A-1ve0A:
undetectable		 4n09A-1ve0A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 1ve0 HYPOTHETICAL PROTEIN
(ST2072)
(Sulfurisphaera
tokodaii) 		3 / 3 THR A  12
GLU A 118
HIS A  43
 None
None
SO4  A 135 (-4.1A)
 0.92A 5xioA-1ve0A:
undetectable		 5xioA-1ve0A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1ve0 HYPOTHETICAL PROTEIN
(ST2072)
(Sulfurisphaera
tokodaii) 		3 / 3 THR A  12
GLU A 118
HIS A  43
 None
None
SO4  A 135 (-4.1A)
 0.87A 5xiqB-1ve0A:
undetectable		 5xiqB-1ve0A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1ve0 HYPOTHETICAL PROTEIN
(ST2072)
(Sulfurisphaera
tokodaii) 		3 / 3 THR A  12
GLU A 118
HIS A  43
 None
None
SO4  A 135 (-4.1A)
 0.93A 5xiqD-1ve0A:
undetectable		 5xiqD-1ve0A:
15.09