SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ve2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4001_1
(SERUM ALBUMIN)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		5 / 9 LEU A 215
LEU A 129
VAL A 222
GLY A 219
ALA A 183
 None
 1.30A 1e7aA-1ve2A:
undetectable		 1e7aA-1ve2A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		5 / 9 GLY A 120
ALA A 121
SER A 123
LEU A 122
LEU A 185
 None
 1.35A 1y7iA-1ve2A:
undetectable		 1y7iA-1ve2A:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		4 / 5 SER A 117
ARG A  94
GLY A  95
GLU A  97
 None
 1.06A 3k9fA-1ve2A:
undetectable
3k9fB-1ve2A:
undetectable
3k9fC-1ve2A:
2.3		 3k9fA-1ve2A:
18.33
3k9fB-1ve2A:
18.33
3k9fC-1ve2A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		4 / 6 SER A 117
ARG A  94
GLY A  95
GLU A  97
 None
 1.06A 3k9fA-1ve2A:
undetectable
3k9fB-1ve2A:
undetectable
3k9fD-1ve2A:
2.3		 3k9fA-1ve2A:
18.33
3k9fB-1ve2A:
18.33
3k9fD-1ve2A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		5 / 8 VAL A  25
LEU A  26
VAL A   8
ARG A  83
LEU A  84
 None
 1.40A 3kp6A-1ve2A:
undetectable
3kp6B-1ve2A:
undetectable		 3kp6A-1ve2A:
20.17
3kp6B-1ve2A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 ALA A  46
VAL A  38
VAL A  42
LEU A  26
 None
 0.74A 3o14A-1ve2A:
undetectable		 3o14A-1ve2A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		5 / 12 GLY A  95
GLY A  93
ILE A  67
LEU A   7
VAL A 111
 None
 1.03A 4gc9A-1ve2A:
undetectable		 4gc9A-1ve2A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		5 / 12 ARG A  83
PRO A  89
LYS A  21
LEU A  84
GLY A  48
 None
 1.28A 4l9qA-1ve2A:
undetectable		 4l9qA-1ve2A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		4 / 5 ARG A  94
GLY A  95
GLU A  97
SER A 117
 None
 0.88A 4z3oA-1ve2A:
2.1
4z3oB-1ve2A:
2.3		 4z3oA-1ve2A:
15.09
4z3oB-1ve2A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		5 / 12 ALA A  46
LEU A  84
LEU A  23
HIS A  39
LEU A  50
 None
 0.99A 4zn7A-1ve2A:
undetectable		 4zn7A-1ve2A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 SER A 117
ARG A  94
GLY A  95
GLU A  97
 None
 1.03A 5btfA-1ve2A:
undetectable
5btfC-1ve2A:
undetectable
5btfD-1ve2A:
undetectable		 5btfA-1ve2A:
19.88
5btfC-1ve2A:
19.88
5btfD-1ve2A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		4 / 5 SER A 117
ARG A  94
GLY A  95
GLU A  97
 None
 1.11A 5btiA-1ve2A:
undetectable
5btiB-1ve2A:
undetectable		 5btiA-1ve2A:
19.88
5btiB-1ve2A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		4 / 5 SER A 117
ARG A  94
GLY A  95
GLU A  97
 None
 1.07A 5btiC-1ve2A:
undetectable
5btiD-1ve2A:
undetectable		 5btiC-1ve2A:
19.88
5btiD-1ve2A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		4 / 5 SER A 117
ARG A  94
GLY A  95
GLU A  97
 None
 1.09A 5cdqA-1ve2A:
undetectable
5cdqB-1ve2A:
2.4
5cdqC-1ve2A:
undetectable		 5cdqA-1ve2A:
19.67
5cdqB-1ve2A:
21.99
5cdqC-1ve2A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		4 / 5 SER A 117
ARG A  94
GLY A  95
GLU A  97
 None
 1.09A 5cdqR-1ve2A:
undetectable
5cdqS-1ve2A:
2.4
5cdqT-1ve2A:
undetectable		 5cdqR-1ve2A:
19.67
5cdqS-1ve2A:
21.99
5cdqT-1ve2A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		4 / 8 LEU A 122
LEU A 129
LEU A 159
LEU A 215
 None
 0.66A 5jqbA-1ve2A:
undetectable
5jqbB-1ve2A:
undetectable		 5jqbA-1ve2A:
20.35
5jqbB-1ve2A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE
(Thermus
thermophilus) 		4 / 6 LEU A 215
VAL A 157
LEU A 129
VAL A 140
 None
 0.91A 5x7zA-1ve2A:
undetectable		 5x7zA-1ve2A:
24.58