SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vel'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 7 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.11A 1v55C-1velA:
5.5
1v55N-1velA:
1.3
1v55P-1velA:
5.5
1v55C-1velA:
17.80
1v55N-1velA:
17.45
1v55P-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 ASP A  30
THR A  27
TYR A  28
LEU A  35
None
1.13A 3ablA-1velA:
1.7
3ablC-1velA:
5.5
3ablP-1velA:
5.5
3ablA-1velA:
17.45
3ablC-1velA:
17.80
3ablP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.11A 3ablC-1velA:
5.5
3ablN-1velA:
4.3
3ablP-1velA:
5.5
3ablC-1velA:
17.80
3ablN-1velA:
17.45
3ablP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 ASP A  30
THR A  27
TYR A  28
LEU A  35
None
1.16A 3abmA-1velA:
4.1
3abmC-1velA:
5.4
3abmP-1velA:
5.5
3abmA-1velA:
17.45
3abmC-1velA:
17.80
3abmP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.12A 3asnC-1velA:
5.5
3asnN-1velA:
3.3
3asnP-1velA:
5.4
3asnC-1velA:
17.80
3asnN-1velA:
17.45
3asnP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 ASP A  30
THR A  27
TYR A  28
LEU A  35
None
1.18A 3asoA-1velA:
2.4
3asoC-1velA:
5.5
3asoP-1velA:
5.5
3asoA-1velA:
17.45
3asoC-1velA:
17.80
3asoP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.14A 3asoC-1velA:
5.5
3asoN-1velA:
6.4
3asoP-1velA:
5.5
3asoC-1velA:
17.80
3asoN-1velA:
17.45
3asoP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
5 / 12 VAL A 116
LEU A  60
TYR A  28
LEU A  31
GLY A 143
None
1.03A 3n8wA-1velA:
undetectable
3n8wA-1velA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
5 / 12 GLY A  63
ALA A  65
ALA A  69
LEU A  25
ASN A  29
None
1.13A 3p5nA-1velA:
undetectable
3p5nA-1velA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
5 / 12 GLY A  63
ALA A  65
ALA A  69
LEU A  25
ASN A  29
None
1.13A 3p5nB-1velA:
undetectable
3p5nB-1velA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
5 / 12 VAL A 116
LEU A  60
TYR A  28
LEU A  31
GLY A 143
None
1.10A 3rr3C-1velA:
undetectable
3rr3C-1velA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
5 / 12 VAL A 116
LEU A  60
TYR A  28
LEU A  31
GLY A 143
None
1.11A 3rr3D-1velA:
undetectable
3rr3D-1velA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.15A 3x2qC-1velA:
5.4
3x2qN-1velA:
undetectable
3x2qP-1velA:
5.5
3x2qC-1velA:
17.80
3x2qN-1velA:
17.45
3x2qP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 5 TYR A 113
GLN A  57
ASP A  30
ASP A  89
None
1.28A 4qtuB-1velA:
undetectable
4qtuB-1velA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 ASP A  30
THR A  27
TYR A  28
LEU A  35
None
1.09A 5b1bA-1velA:
3.5
5b1bC-1velA:
5.5
5b1bP-1velA:
5.5
5b1bA-1velA:
17.45
5b1bC-1velA:
17.80
5b1bP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.10A 5iy5C-1velA:
5.6
5iy5N-1velA:
1.5
5iy5P-1velA:
5.5
5iy5C-1velA:
19.01
5iy5N-1velA:
17.45
5iy5P-1velA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 ASP A  30
THR A  27
TYR A  28
LEU A  35
None
1.07A 5w97A-1velA:
4.9
5w97C-1velA:
5.5
5w97c-1velA:
5.5
5w97A-1velA:
17.45
5w97C-1velA:
17.80
5w97c-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 7 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.11A 5w97C-1velA:
5.5
5w97a-1velA:
1.2
5w97c-1velA:
5.5
5w97C-1velA:
17.80
5w97a-1velA:
17.45
5w97c-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 ASP A  30
THR A  27
TYR A  28
LEU A  35
None
1.12A 5wauA-1velA:
1.5
5wauC-1velA:
5.5
5wauc-1velA:
5.5
5wauA-1velA:
17.45
5wauC-1velA:
17.80
5wauc-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 7 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.13A 5wauC-1velA:
5.4
5waua-1velA:
4.9
5wauc-1velA:
5.4
5wauC-1velA:
17.80
5waua-1velA:
17.45
5wauc-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 ASP A  30
THR A  27
TYR A  28
LEU A  35
None
1.04A 5x19A-1velA:
1.9
5x19C-1velA:
5.4
5x19P-1velA:
5.4
5x19A-1velA:
17.45
5x19C-1velA:
17.80
5x19P-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 7 ASP A  30
THR A  27
TYR A  28
LEU A  35
None
1.01A 5x1bA-1velA:
2.6
5x1bC-1velA:
5.4
5x1bP-1velA:
5.5
5x1bA-1velA:
17.45
5x1bC-1velA:
17.80
5x1bP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 7 ASP A  30
THR A  27
TYR A  28
LEU A  35
None
1.01A 5x1fA-1velA:
5.8
5x1fC-1velA:
5.5
5x1fP-1velA:
5.5
5x1fA-1velA:
17.45
5x1fC-1velA:
17.80
5x1fP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 ASP A  30
THR A  27
TYR A  28
LEU A  35
None
1.18A 5xdqA-1velA:
undetectable
5xdqC-1velA:
5.6
5xdqP-1velA:
5.5
5xdqA-1velA:
17.45
5xdqC-1velA:
17.80
5xdqP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.11A 5xdqC-1velA:
5.6
5xdqN-1velA:
4.0
5xdqP-1velA:
5.5
5xdqC-1velA:
17.80
5xdqN-1velA:
17.45
5xdqP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.10A 5xdxC-1velA:
3.3
5xdxN-1velA:
4.1
5xdxP-1velA:
5.5
5xdxC-1velA:
19.01
5xdxN-1velA:
17.45
5xdxP-1velA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 7 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.11A 5z84C-1velA:
5.5
5z84N-1velA:
1.5
5z84P-1velA:
5.5
5z84C-1velA:
17.80
5z84N-1velA:
17.45
5z84P-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 7 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.14A 5z85C-1velA:
5.4
5z85N-1velA:
1.5
5z85P-1velA:
5.5
5z85C-1velA:
17.80
5z85N-1velA:
17.45
5z85P-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.13A 5z86C-1velA:
5.5
5z86N-1velA:
undetectable
5z86P-1velA:
5.5
5z86C-1velA:
17.80
5z86N-1velA:
17.45
5z86P-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.14A 5zcoC-1velA:
5.5
5zcoN-1velA:
4.3
5zcoP-1velA:
5.4
5zcoC-1velA:
17.80
5zcoN-1velA:
17.45
5zcoP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
1.14A 5zcpC-1velA:
5.5
5zcpN-1velA:
undetectable
5zcpP-1velA:
5.5
5zcpC-1velA:
17.80
5zcpN-1velA:
17.45
5zcpP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 8 LEU A  35
ASP A  30
THR A  27
TYR A  28
None
0.99A 6nknC-1velA:
5.5
6nknN-1velA:
1.8
6nknP-1velA:
5.4
6nknC-1velA:
17.80
6nknN-1velA:
17.45
6nknP-1velA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1vel STARVATION-INDUCED
DNA PROTECTING
PROTEIN

(Mycolicibacteriu
m
smegmatis)
4 / 7 ASP A  30
THR A  27
TYR A  28
LEU A  35
None
0.91A 6nmfA-1velA:
undetectable
6nmfC-1velA:
5.4
6nmfP-1velA:
5.4
6nmfA-1velA:
17.45
6nmfC-1velA:
17.80
6nmfP-1velA:
17.80