SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ven'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 6 GLY A 441
TYR A 454
ALA A 444
GLU A 383
 None
 0.89A 1dmaB-1venA:
undetectable		 1dmaB-1venA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		5 / 12 TYR A 388
LEU A 349
LEU A 356
TYR A 313
ILE A 353
 None
 1.24A 1fmlA-1venA:
undetectable		 1fmlA-1venA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		5 / 12 TYR A 388
LEU A 349
LEU A 356
TYR A 313
ILE A 353
 None
 1.24A 1fmlB-1venA:
undetectable		 1fmlB-1venA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		3 / 3 ASP A  97
HIS A  89
ASP A  49
 GLC  A 900 (-2.8A)
GLC  A 900 (-4.0A)
GLC  A 900 (-2.9A)
 0.76A 1nw5A-1venA:
undetectable		 1nw5A-1venA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 8 TYR A 178
CYH A 331
TRP A 293
LEU A 349
 GLC  A 903 (-4.5A)
None
None
None
 1.39A 1uw6A-1venA:
undetectable
1uw6B-1venA:
undetectable		 1uw6A-1venA:
17.63
1uw6B-1venA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 8 TYR A 178
CYH A 331
TRP A 293
LEU A 349
 GLC  A 903 (-4.5A)
None
None
None
 1.35A 1uw6D-1venA:
undetectable
1uw6E-1venA:
undetectable		 1uw6D-1venA:
17.63
1uw6E-1venA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 8 TRP A 293
LEU A 349
TYR A 178
CYH A 331
 None
None
GLC  A 903 (-4.5A)
None
 1.31A 1uw6P-1venA:
undetectable
1uw6T-1venA:
undetectable		 1uw6P-1venA:
17.63
1uw6T-1venA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		3 / 3 HIS A  89
ILE A 103
LEU A 145
 GLC  A 900 (-4.0A)
None
None
 0.72A 2kceA-1venA:
undetectable		 2kceA-1venA:
18.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XFF_A_QPSA600_1
(BETA-AMYLASE)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		8 / 12 ALA A 170
GLU A 172
ARG A 174
TYR A 178
GLY A 290
HIS A 292
THR A 330
MET A 334
 GLC  A 900 ( 4.0A)
None
None
GLC  A 903 (-4.5A)
None
GLC  A 903 (-4.2A)
None
GLC  A 903 (-4.2A)
 0.40A 2xffA-1venA:
41.4		 2xffA-1venA:
31.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 6 TYR A  67
ARG A  70
PHE A  71
PHE A  31
 None
 1.43A 3af3A-1venA:
0.0		 3af3A-1venA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 5 PRO A 419
VAL A 417
THR A 440
GLY A 447
 None
 1.20A 3elzB-1venA:
undetectable		 3elzB-1venA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		5 / 12 HIS A  89
SER A  87
THR A  88
GLY A 168
LEU A 165
 GLC  A 900 (-4.0A)
GLC  A 900 ( 4.3A)
None
None
None
 1.15A 3fzgA-1venA:
undetectable		 3fzgA-1venA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		5 / 12 HIS A  89
SER A  87
THR A  88
GLY A 171
LEU A 165
 GLC  A 900 (-4.0A)
GLC  A 900 ( 4.3A)
None
GLC  A 900 ( 4.9A)
None
 1.26A 3fzgA-1venA:
undetectable		 3fzgA-1venA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 6 PRO A 169
LEU A 261
ALA A 308
PRO A 176
 None
 0.96A 3gv1A-1venA:
undetectable
3gv1C-1venA:
undetectable		 3gv1A-1venA:
14.09
3gv1C-1venA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 6 LEU A 261
ALA A 308
PRO A 176
PRO A 169
 None
 1.00A 3gv1A-1venA:
undetectable
3gv1B-1venA:
undetectable		 3gv1A-1venA:
14.09
3gv1B-1venA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		6 / 12 GLY A 168
GLY A 167
ALA A 286
ALA A 170
PRO A 176
TYR A 310
 None
None
None
GLC  A 900 ( 4.0A)
None
None
 1.18A 3jayA-1venA:
undetectable		 3jayA-1venA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 7 ARG A 204
VAL A 207
VAL A 217
LEU A 225
 None
 0.82A 3o14A-1venA:
undetectable		 3o14A-1venA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 5 LEU A 173
GLY A 168
THR A 129
ILE A 138
 None
 0.92A 3wriA-1venA:
1.6		 3wriA-1venA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		3 / 3 ASP A 136
TRP A 106
SER A 115
 None
 1.05A 4lrhA-1venA:
undetectable		 4lrhA-1venA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 4 LEU A 395
SER A 371
LEU A 407
LEU A  15
 None
 1.00A 4n09A-1venA:
2.2		 4n09A-1venA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		3 / 3 THR A 335
ASN A 387
PHE A 386
 None
 0.72A 4pd9A-1venA:
undetectable		 4pd9A-1venA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		3 / 3 PRO A 307
VAL A 291
HIS A 292
 None
None
GLC  A 903 (-4.2A)
 0.83A 4pevC-1venA:
undetectable		 4pevC-1venA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RV6_A_RPBA1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		5 / 11 GLN A 258
GLY A 244
TYR A 257
TYR A 253
SER A 247
 None
 1.42A 4rv6A-1venA:
undetectable		 4rv6A-1venA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RV6_B_RPBB1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		5 / 11 GLN A 258
GLY A 244
TYR A 257
TYR A 253
SER A 247
 None
 1.41A 4rv6B-1venA:
undetectable		 4rv6B-1venA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 5 LEU A 395
ALA A  13
LEU A  15
VAL A 417
 None
 0.95A 5cr1A-1venA:
undetectable		 5cr1A-1venA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 6 GLY A 168
ILE A 353
TYR A 310
TYR A 178
 None
None
None
GLC  A 903 (-4.5A)
 0.98A 5iwuA-1venA:
undetectable		 5iwuA-1venA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 6 GLY A 171
ILE A 353
TYR A 310
TYR A 178
 GLC  A 900 ( 4.9A)
None
None
GLC  A 903 (-4.5A)
 0.97A 5iwuA-1venA:
undetectable		 5iwuA-1venA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 6 GLU A 121
PRO A 307
GLY A 237
ARG A 189
 None
 1.22A 5jcnB-1venA:
0.4		 5jcnB-1venA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		3 / 3 ARG A 174
PRO A 169
ASN A 126
 None
 0.87A 5jwaA-1venA:
undetectable
5jwaH-1venA:
undetectable		 5jwaA-1venA:
22.22
5jwaH-1venA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		5 / 12 GLY A 250
TYR A 211
ASN A 218
THR A 223
LEU A 225
 None
 1.45A 5lsuB-1venA:
undetectable		 5lsuB-1venA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M10_A_NCAA603_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 5 LEU A 225
PHE A 203
LEU A 232
TRP A 221
 None
 1.40A 5m10A-1venA:
undetectable		 5m10A-1venA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 6 ASN A 218
THR A 223
ILE A 231
GLU A 228
 None
 1.10A 5uigA-1venA:
undetectable		 5uigA-1venA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		5 / 12 GLY A 285
GLU A 164
LYS A 162
ILE A  85
LEU A 396
 None
 1.20A 5ul4A-1venA:
2.1		 5ul4A-1venA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		4 / 7 ALA A 148
THR A 147
TYR A 146
PRO A 104
 None
 0.96A 6cduA-1venA:
undetectable
6cduE-1venA:
undetectable		 6cduA-1venA:
20.46
6cduE-1venA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 1ven BETA-AMYLASE
(Bacillus
cereus) 		3 / 3 TYR A 403
ASP A 400
GLN A 399
 None
 0.90A 6g1pA-1venA:
undetectable		 6g1pA-1venA:
21.69