SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vey'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_C_HISC450_0
(HISTIDYL-TRNA
SYNTHETASE)		 1vey PEPTIDE DEFORMYLASE
(Leptospira
interrogans) 		5 / 12 GLU A 144
ARG A  70
TYR A  71
GLY A  46
GLY A  48
 EPE  A1716 (-3.1A)
EPE  A1716 (-3.4A)
EPE  A1716 (-3.2A)
EPE  A1716 (-3.1A)
EPE  A1716 (-4.1A)
 1.13A 1httC-1veyA:
undetectable		 1httC-1veyA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 1vey PEPTIDE DEFORMYLASE
(Leptospira
interrogans) 		4 / 7 HIS A 147
LEU A  13
TYR A 153
ILE A   5
 ZN  A1513 (-3.6A)
None
None
None
 1.18A 1tuvA-1veyA:
undetectable		 1tuvA-1veyA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 1vey PEPTIDE DEFORMYLASE
(Leptospira
interrogans) 		5 / 12 MET A  37
GLY A  48
VAL A 140
LEU A 148
ILE A  82
 None
EPE  A1716 (-4.1A)
EPE  A1716 ( 4.9A)
None
None
 1.38A 3h52A-1veyA:
undetectable		 3h52A-1veyA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 1vey PEPTIDE DEFORMYLASE
(Leptospira
interrogans) 		5 / 12 MET A  37
GLY A  64
VAL A  77
ARG A  70
ILE A  82
 None
None
None
EPE  A1716 (-3.4A)
None
 1.43A 3h52A-1veyA:
undetectable		 3h52A-1veyA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 1vey PEPTIDE DEFORMYLASE
(Leptospira
interrogans) 		5 / 12 MET A  37
LEU A  49
VAL A 140
LEU A 148
ILE A  82
 None
None
EPE  A1716 ( 4.9A)
None
None
 1.39A 3h52A-1veyA:
undetectable		 3h52A-1veyA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 1vey PEPTIDE DEFORMYLASE
(Leptospira
interrogans) 		4 / 7 GLU A 144
TYR A  71
GLY A  46
GLY A  48
 EPE  A1716 (-3.1A)
EPE  A1716 (-3.2A)
EPE  A1716 (-3.1A)
EPE  A1716 (-4.1A)
 0.68A 4rdxA-1veyA:
undetectable		 4rdxA-1veyA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 1vey PEPTIDE DEFORMYLASE
(Leptospira
interrogans) 		4 / 8 HIS A 147
GLU A 144
ASP A 146
ARG A 156
 ZN  A1513 (-3.6A)
EPE  A1716 (-3.1A)
None
None
 1.16A 4uhxA-1veyA:
undetectable		 4uhxA-1veyA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 1vey PEPTIDE DEFORMYLASE
(Leptospira
interrogans) 		4 / 8 HIS A 147
GLU A 144
ASP A 146
ARG A 156
 ZN  A1513 (-3.6A)
EPE  A1716 (-3.1A)
None
None
 1.16A 4uhxA-1veyA:
undetectable		 4uhxA-1veyA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 1vey PEPTIDE DEFORMYLASE
(Leptospira
interrogans) 		4 / 7 PHE A  97
ILE A 139
GLY A 135
THR A  74
 EPE  A1716 (-4.2A)
None
None
EPE  A1716 ( 4.7A)
 1.15A 4zxiA-1veyA:
undetectable		 4zxiA-1veyA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_A_SALA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1vey PEPTIDE DEFORMYLASE
(Leptospira
interrogans) 		4 / 8 VAL A 154
LEU A 157
LEU A 169
GLY A 164
 None
 0.83A 5f1aA-1veyA:
undetectable		 5f1aA-1veyA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1vey PEPTIDE DEFORMYLASE
(Leptospira
interrogans) 		5 / 12 ILE A  60
PRO A  85
LEU A 148
GLU A 124
ARG A  80
 None
 1.31A 5k7uA-1veyA:
undetectable		 5k7uA-1veyA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 1vey PEPTIDE DEFORMYLASE
(Leptospira
interrogans) 		3 / 3 HIS A 147
HIS A 143
ARG A 113
 ZN  A1513 (-3.6A)
ZN  A1513 (-3.8A)
None
 1.10A 6b58A-1veyA:
undetectable		 6b58A-1veyA:
15.46