SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vf1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		5 / 12 ALA A 156
ASP A 157
LEU A 160
MET A  94
ARG A  69
 None
 1.17A 1errA-1vf1A:
undetectable		 1errA-1vf1A:
23.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		5 / 12 ARG A  13
GLY A  14
LYS A  15
LEU A 107
PRO A 110
 None
None
GSH  A2457 (-3.6A)
None
None
 1.20A 1gseA-1vf1A:
32.8		 1gseA-1vf1A:
64.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		5 / 12 TYR A   9
ARG A  13
GLY A  14
LYS A  15
LEU A 107
 None
None
None
GSH  A2457 (-3.6A)
None
 0.91A 1gseA-1vf1A:
32.8		 1gseA-1vf1A:
64.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		5 / 12 TYR A   9
PHE A  10
GLY A  14
LYS A  15
LEU A 107
 None
None
None
GSH  A2457 (-3.6A)
None
 1.25A 1gseA-1vf1A:
32.8		 1gseA-1vf1A:
64.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		5 / 12 TYR A   9
ARG A  13
GLY A  14
LYS A  15
LEU A 107
 None
None
None
GSH  A2457 (-3.6A)
None
 0.94A 1gseB-1vf1A:
32.8		 1gseB-1vf1A:
64.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		5 / 11 ALA A 156
LEU A 160
LEU A 148
LEU A 140
ALA A 135
 None
 1.13A 1h9zA-1vf1A:
undetectable		 1h9zA-1vf1A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_1
(AMINOMETHYLTRANSFERA
SE)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		4 / 4 ASP A 209
GLU A  36
ARG A 218
TYR A   9
 None
 1.43A 1wsvB-1vf1A:
0.0		 1wsvB-1vf1A:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		4 / 5 LEU A  72
GLY A  27
ALA A  76
ILE A  75
 None
 0.82A 2aohB-1vf1A:
undetectable		 2aohB-1vf1A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		4 / 6 LEU A 161
GLU A 168
ALA A 163
THR A  99
 None
 1.07A 2roxB-1vf1A:
undetectable		 2roxB-1vf1A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		5 / 11 HIS A 143
GLU A  88
VAL A 139
GLY A  83
ILE A  92
 None
 1.20A 2uxpB-1vf1A:
undetectable		 2uxpB-1vf1A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		3 / 3 ARG A  13
ARG A  20
PRO A 206
 None
 1.08A 2wljA-1vf1A:
undetectable		 2wljA-1vf1A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		5 / 12 ASP A  93
VAL A  96
TRP A 155
ASN A  73
TYR A  82
 None
 0.83A 3d4sA-1vf1A:
undetectable		 3d4sA-1vf1A:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		5 / 12 ASP A  93
VAL A  96
TRP A 155
ASN A  73
TYR A  82
 None
 0.90A 4amjA-1vf1A:
undetectable		 4amjA-1vf1A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		5 / 12 ASP A  93
VAL A  96
TRP A 155
ASN A  73
TYR A  82
 None
 0.89A 4amjB-1vf1A:
undetectable		 4amjB-1vf1A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		5 / 12 ALA A 156
ASP A 157
LEU A 160
MET A  94
ARG A  69
 None
 1.12A 4xi3A-1vf1A:
undetectable		 4xi3A-1vf1A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		4 / 8 TYR A 223
ILE A  19
SER A  18
GLY A  14
 None
 0.82A 5alcL-1vf1A:
undetectable		 5alcL-1vf1A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		4 / 6 MET A 103
GLY A  97
ALA A 156
LEU A 160
 None
 1.06A 6fosA-1vf1A:
undetectable		 6fosA-1vf1A:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		5 / 11 ASN A  73
HIS A 159
THR A  99
GLY A  97
ASP A 101
 None
 1.10A 6mb5A-1vf1A:
undetectable		 6mb5A-1vf1A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB7_A_PARA900_0
(AAC(3)-IIIB PROTEIN)		 1vf1 GLUTATHIONE
S-TRANSFERASE 3
(Gallus
gallus) 		5 / 10 ASN A  73
HIS A 159
THR A  99
GLY A  97
ASP A 101
 None
 1.09A 6mb7A-1vf1A:
undetectable		 6mb7A-1vf1A:
19.21