SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vf6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 1vf6 MAGUK P55 SUBFAMILY
MEMBER 5
(Mus
musculus) 		5 / 12 ILE C 147
SER C 129
LYS C 132
LEU C 150
LEU C 127
 None
 1.30A 1lbcA-1vf6C:
undetectable
1lbcC-1vf6C:
undetectable		 1lbcA-1vf6C:
11.79
1lbcC-1vf6C:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 1vf6 PALS1-ASSOCIATED
TIGHT JUNCTION
PROTEIN
(Homo
sapiens) 		3 / 3 ASP A  28
LYS A  22
ARG A  18
 None
 1.14A 1ra8A-1vf6A:
undetectable		 1ra8A-1vf6A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vf6 PALS1-ASSOCIATED
TIGHT JUNCTION
PROTEIN
(Homo
sapiens) 		4 / 6 LEU A  13
GLN A  14
LEU A  42
PHE A  38
 None
 0.97A 3ag1C-1vf6A:
undetectable
3ag1J-1vf6A:
undetectable		 3ag1C-1vf6A:
14.56
3ag1J-1vf6A:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 1vf6 MAGUK P55 SUBFAMILY
MEMBER 5
PALS1-ASSOCIATED
TIGHT JUNCTION
PROTEIN
(Homo
sapiens;
Mus
musculus) 		4 / 5 LEU A  19
LEU A  16
LEU C 149
SER C 148
 None
 1.02A 3vhuA-1vf6A:
undetectable		 3vhuA-1vf6A:
16.43