SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vf8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		9 / 9 TYR A   6
PHE A  37
GLY A  77
ASP A 117
GLN A 119
MET A 189
TYR A 191
ASP A 192
TRP A 339
 None
 0.57A 1e9lA-1vf8A:
64.1		 1e9lA-1vf8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_A_D16A414_1
(THYMIDYLATE SYNTHASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 12 GLU A 148
ILE A 103
LEU A 114
GLY A 113
ALA A  38
 None
 1.12A 1hvyA-1vf8A:
undetectable		 1hvyA-1vf8A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 12 GLU A 148
ILE A 103
LEU A 114
GLY A 113
ALA A  38
 None
 1.19A 1hvyB-1vf8A:
undetectable		 1hvyB-1vf8A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 12 ILE A 226
GLY A 242
VAL A 188
ALA A 245
SER A 205
 None
 1.21A 1nbhA-1vf8A:
undetectable		 1nbhA-1vf8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 12 ILE A 226
GLY A 242
VAL A 188
ALA A 245
SER A 205
 None
 1.21A 1nbhC-1vf8A:
undetectable		 1nbhC-1vf8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 12 ILE A 226
GLY A 242
VAL A 188
ALA A 245
SER A 205
 None
 1.22A 1nbhD-1vf8A:
undetectable		 1nbhD-1vf8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		4 / 5 VAL A 241
GLY A 242
VAL A 188
TRP A 339
 None
 1.23A 1tkqB-1vf8A:
undetectable		 1tkqB-1vf8A:
3.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		4 / 7 PRO A 269
LEU A 280
GLY A 247
PRO A 196
 None
 0.90A 1ya4B-1vf8A:
undetectable		 1ya4B-1vf8A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		7 / 11 PHE A  37
GLY A  77
ASP A 117
MET A 189
TYR A 191
ASP A 192
TYR A 246
 None
 0.78A 2a3aA-1vf8A:
14.4		 2a3aA-1vf8A:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		7 / 11 TYR A   6
PHE A  37
GLY A  77
MET A 189
TYR A 191
ASP A 192
TYR A 246
 None
 0.62A 2a3aA-1vf8A:
14.4		 2a3aA-1vf8A:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		7 / 11 TYR A   6
PHE A  37
GLY A  77
TRP A  78
MET A 189
TYR A 191
TYR A 246
 None
 0.87A 2a3aA-1vf8A:
14.4		 2a3aA-1vf8A:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 9 PHE A  37
GLY A  77
ASP A 192
TYR A 246
TRP A 339
 None
 0.91A 2a3aB-1vf8A:
44.1		 2a3aB-1vf8A:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		6 / 9 PHE A  37
GLY A  77
MET A 189
TYR A 191
ASP A 192
TYR A 246
 None
 0.42A 2a3aB-1vf8A:
44.1		 2a3aB-1vf8A:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		7 / 11 TYR A   6
PHE A  37
GLY A  77
MET A 189
TYR A 191
ASP A 192
TYR A 246
 None
 0.63A 2a3bA-1vf8A:
44.1		 2a3bA-1vf8A:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		6 / 10 PHE A  37
GLY A  77
ASP A 117
MET A 189
TYR A 191
TYR A 246
 None
 0.86A 2a3bB-1vf8A:
44.1		 2a3bB-1vf8A:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 10 PHE A  37
GLY A  77
ASP A 192
TYR A 246
TRP A 339
 None
 0.94A 2a3bB-1vf8A:
44.1		 2a3bB-1vf8A:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		6 / 10 PHE A  37
GLY A  77
MET A 189
TYR A 191
ASP A 192
TYR A 246
 None
 0.46A 2a3bB-1vf8A:
44.1		 2a3bB-1vf8A:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		8 / 12 TYR A   6
TRP A  10
PHE A  37
GLY A  77
ASP A 117
MET A 189
TYR A 191
TYR A 246
 None
 0.89A 2a3cA-1vf8A:
13.8		 2a3cA-1vf8A:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		8 / 12 TYR A   6
TRP A  10
PHE A  37
GLY A  77
MET A 189
TYR A 191
ASP A 192
TYR A 246
 None
 0.61A 2a3cA-1vf8A:
13.8		 2a3cA-1vf8A:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		7 / 12 TRP A  10
PHE A  37
GLY A  77
ASP A 117
MET A 189
TYR A 191
TYR A 246
 None
 0.82A 2a3cB-1vf8A:
44.1		 2a3cB-1vf8A:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		7 / 12 TRP A  10
PHE A  37
GLY A  77
MET A 189
TYR A 191
ASP A 192
TYR A 246
 None
 0.47A 2a3cB-1vf8A:
44.1		 2a3cB-1vf8A:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		4 / 7 VAL A 222
SER A 205
LEU A 328
PHE A 321
 None
 1.11A 2f78A-1vf8A:
undetectable		 2f78A-1vf8A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		4 / 5 ASP A 184
LEU A 159
MET A 141
ARG A 156
 None
 1.38A 2gj5A-1vf8A:
undetectable		 2gj5A-1vf8A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_ACTA148_0
(UPF0066 PROTEIN
AF_0241)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		3 / 3 VAL A 150
GLU A 146
GLU A 147
 None
 0.81A 2nv4A-1vf8A:
undetectable		 2nv4A-1vf8A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 9 LEU A 116
ILE A  75
GLY A  76
GLY A  77
LEU A  72
 None
 1.14A 2qmmA-1vf8A:
undetectable		 2qmmA-1vf8A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 9 TYR A   6
PHE A  37
GLY A  77
ASP A 117
TRP A 339
 None
 0.77A 2uy4A-1vf8A:
19.7		 2uy4A-1vf8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 9 TYR A   6
PHE A  37
GLY A  77
ASP A 117
TYR A 191
 None
 0.69A 2uy4A-1vf8A:
19.7		 2uy4A-1vf8A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 10 TYR A   6
PHE A  37
GLY A  77
ASP A 117
TRP A 339
 None
 0.78A 2xtkB-1vf8A:
20.7		 2xtkB-1vf8A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 10 TYR A   6
PHE A  37
GLY A  77
ASP A 117
TYR A 191
 None
 0.81A 2xtkB-1vf8A:
20.7		 2xtkB-1vf8A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		4 / 8 GLN A 187
MET A   4
ILE A 240
SER A 180
 None
 1.12A 2xytH-1vf8A:
undetectable		 2xytH-1vf8A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		3 / 3 ASN A  24
ASP A  55
GLN A  51
 None
 0.72A 3eeyC-1vf8A:
undetectable		 3eeyC-1vf8A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		3 / 3 ASN A  24
ASP A  55
GLN A  51
 None
 0.72A 3eeyD-1vf8A:
undetectable		 3eeyD-1vf8A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		3 / 3 ASN A  24
ASP A  55
GLN A  51
 None
 0.73A 3eeyE-1vf8A:
undetectable		 3eeyE-1vf8A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		7 / 11 PHE A  37
GLY A  77
TRP A  78
ASP A 117
MET A 189
TYR A 191
TYR A 246
 None
 0.92A 3g6mA-1vf8A:
44.7		 3g6mA-1vf8A:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		6 / 11 PHE A  37
GLY A  77
TRP A  78
ASP A 192
TYR A 246
TRP A 339
 None
 0.96A 3g6mA-1vf8A:
44.7		 3g6mA-1vf8A:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		7 / 11 PHE A  37
GLY A  77
TRP A  78
MET A 189
TYR A 191
ASP A 192
TYR A 246
 None
 0.61A 3g6mA-1vf8A:
44.7		 3g6mA-1vf8A:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		7 / 11 TYR A   6
PHE A  37
GLY A  77
ASP A 117
MET A 189
TYR A 191
TYR A 246
 None
 0.95A 3g6mA-1vf8A:
44.7		 3g6mA-1vf8A:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		6 / 11 TYR A   6
PHE A  37
GLY A  77
ASP A 192
TYR A 246
TRP A 339
 None
 1.02A 3g6mA-1vf8A:
44.7		 3g6mA-1vf8A:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		7 / 11 TYR A   6
PHE A  37
GLY A  77
MET A 189
TYR A 191
ASP A 192
TYR A 246
 None
 0.62A 3g6mA-1vf8A:
44.7		 3g6mA-1vf8A:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA427_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		4 / 5 TRP A  78
TYR A 120
MET A 189
ASP A 192
 None
 0.62A 3g6mA-1vf8A:
44.7		 3g6mA-1vf8A:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		4 / 6 GLN A 187
MET A   4
ILE A 240
SER A 180
 None
 0.90A 3pmzD-1vf8A:
undetectable		 3pmzD-1vf8A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 12 GLY A 202
SER A 210
GLY A 259
LEU A 193
ASP A 192
 None
 1.43A 3r24A-1vf8A:
undetectable		 3r24A-1vf8A:
20.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQV_A_GCSA501_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		7 / 11 PHE A  37
GLY A  77
TRP A  78
ASP A 117
ASP A 192
TYR A 246
TRP A 339
 None
 0.83A 3wqvA-1vf8A:
54.8		 3wqvA-1vf8A:
37.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQV_A_GCSA501_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		8 / 11 PHE A  37
GLY A  77
TRP A  78
ASP A 117
MET A 189
TYR A 191
ASP A 192
TYR A 246
 None
 0.49A 3wqvA-1vf8A:
54.8		 3wqvA-1vf8A:
37.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQW_A_GCSA501_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		8 / 11 PHE A  37
GLY A  77
TRP A  78
ASP A 117
MET A 189
ASP A 192
TYR A 246
TRP A 339
 None
 0.79A 3wqwA-1vf8A:
54.9		 3wqwA-1vf8A:
37.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQW_A_GCSA501_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		8 / 11 PHE A  37
GLY A  77
TRP A  78
ASP A 117
MET A 189
TYR A 191
ASP A 192
TYR A 246
 None
 0.51A 3wqwA-1vf8A:
54.9		 3wqwA-1vf8A:
37.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		4 / 8 PHE A 250
TRP A 312
PRO A 206
GLN A 301
 None
 1.00A 4j7uD-1vf8A:
undetectable		 4j7uD-1vf8A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		3 / 3 PRO A  82
ILE A  97
SER A 123
 None
 0.79A 5fsaA-1vf8A:
undetectable		 5fsaA-1vf8A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 8 PHE A  37
GLY A  77
TRP A  78
ASP A 192
TRP A 339
 None
 0.85A 5gqbA-1vf8A:
43.6		 5gqbA-1vf8A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 8 PHE A  37
GLY A  77
TRP A  78
TYR A 191
ASP A 192
 None
 0.54A 5gqbA-1vf8A:
43.6		 5gqbA-1vf8A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 12 ASP A 198
ASP A 316
PRO A 206
GLY A 314
TYR A 305
 None
 1.23A 5hfjH-1vf8A:
undetectable		 5hfjH-1vf8A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		4 / 5 PRO A 269
HIS A 248
LEU A 289
TYR A 283
 None
 1.45A 5igjA-1vf8A:
undetectable		 5igjA-1vf8A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 10 PRO A 269
LEU A 279
PRO A 244
ALA A 245
VAL A 285
 None
 1.37A 5m0oA-1vf8A:
undetectable		 5m0oA-1vf8A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		4 / 4 ILE A 225
LEU A 239
HIS A 232
ALA A 234
 None
 0.82A 6ck2C-1vf8A:
undetectable
6ck2D-1vf8A:
undetectable		 6ck2C-1vf8A:
5.00
6ck2D-1vf8A:
6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_2
(PROTEASE)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		3 / 3 GLY A 215
ASP A 219
ILE A 166
 None
 0.56A 6dgxB-1vf8A:
undetectable		 6dgxB-1vf8A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 12 VAL A 222
ASP A 223
LEU A 366
SER A 205
LEU A 362
 None
 1.18A 6ew0F-1vf8A:
undetectable		 6ew0F-1vf8A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 1vf8 SECRETORY PROTEIN
(Mus
musculus) 		5 / 12 VAL A 222
ASP A 223
LEU A 366
SER A 205
LEU A 362
 None
 1.18A 6ew0G-1vf8A:
undetectable		 6ew0G-1vf8A:
12.60