SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vgg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 1vgg CONSERVED
HYPOTHETICAL PROTEIN
TT1634 (TTHA1091)
(Thermus
thermophilus) 		5 / 11 LEU A  83
VAL A 132
GLY A 131
ALA A 110
LEU A 116
 None
 1.27A 2bxgA-1vggA:
undetectable		 2bxgA-1vggA:
16.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GL0_A_ADNA901_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1vgg CONSERVED
HYPOTHETICAL PROTEIN
TT1634 (TTHA1091)
(Thermus
thermophilus) 		5 / 10 ASN A  15
ILE A  93
ALA A 113
ASN A 114
TYR A 159
 None
 0.40A 2gl0A-1vggA:
25.8
2gl0B-1vggA:
26.1		 2gl0A-1vggA:
57.65
2gl0B-1vggA:
57.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GL0_B_ADNB902_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1vgg CONSERVED
HYPOTHETICAL PROTEIN
TT1634 (TTHA1091)
(Thermus
thermophilus) 		6 / 11 ASN A  15
ILE A  93
THR A 112
ALA A 113
ASN A 114
TYR A 159
 None
 0.41A 2gl0B-1vggA:
26.1
2gl0C-1vggA:
26.2		 2gl0B-1vggA:
57.65
2gl0C-1vggA:
57.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1vgg CONSERVED
HYPOTHETICAL PROTEIN
TT1634 (TTHA1091)
(Thermus
thermophilus) 		6 / 12 ASN A  15
ILE A  93
THR A 112
ALA A 113
ASN A 114
TYR A 159
 None
 0.49A 2gl0A-1vggA:
25.8
2gl0C-1vggA:
26.2		 2gl0A-1vggA:
57.65
2gl0C-1vggA:
57.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1vgg CONSERVED
HYPOTHETICAL PROTEIN
TT1634 (TTHA1091)
(Thermus
thermophilus) 		6 / 12 ASN A  15
ILE A  93
THR A 112
ALA A 113
ASN A 114
TYR A 159
 None
 0.45A 2gl0D-1vggA:
26.1
2gl0E-1vggA:
25.8		 2gl0D-1vggA:
57.65
2gl0E-1vggA:
57.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GL0_E_ADNE905_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1vgg CONSERVED
HYPOTHETICAL PROTEIN
TT1634 (TTHA1091)
(Thermus
thermophilus) 		6 / 11 ASN A  15
ILE A  93
THR A 112
ALA A 113
ASN A 114
TYR A 159
 None
 0.43A 2gl0E-1vggA:
25.8
2gl0F-1vggA:
26.2		 2gl0E-1vggA:
57.65
2gl0F-1vggA:
57.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GL0_F_ADNF906_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 1vgg CONSERVED
HYPOTHETICAL PROTEIN
TT1634 (TTHA1091)
(Thermus
thermophilus) 		6 / 11 ASN A  15
ILE A  93
THR A 112
ALA A 113
ASN A 114
TYR A 159
 None
 0.50A 2gl0D-1vggA:
26.1
2gl0F-1vggA:
26.2		 2gl0D-1vggA:
57.65
2gl0F-1vggA:
57.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 1vgg CONSERVED
HYPOTHETICAL PROTEIN
TT1634 (TTHA1091)
(Thermus
thermophilus) 		5 / 12 LEU A  14
GLY A  87
VAL A  66
HIS A  31
VAL A  35
 None
 1.29A 4okwA-1vggA:
undetectable		 4okwA-1vggA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 1vgg CONSERVED
HYPOTHETICAL PROTEIN
TT1634 (TTHA1091)
(Thermus
thermophilus) 		5 / 12 LEU A  14
GLY A  87
VAL A  66
HIS A  31
VAL A  35
 None
 1.29A 4okxA-1vggA:
undetectable		 4okxA-1vggA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1vgg CONSERVED
HYPOTHETICAL PROTEIN
TT1634 (TTHA1091)
(Thermus
thermophilus) 		4 / 7 GLU A  12
LEU A  14
ASN A  72
LEU A  65
 None
 0.72A 4wg0B-1vggA:
undetectable
4wg0C-1vggA:
undetectable		 4wg0B-1vggA:
5.59
4wg0C-1vggA:
5.59