SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vgj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)
1vgj HYPOTHETICAL PROTEIN
PH0099

(Pyrococcus
horikoshii)
4 / 6 HIS A  40
ILE A 126
ALA A  20
VAL A  75
None
1.03A 1hk1A-1vgjA:
undetectable
1hk1A-1vgjA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)
1vgj HYPOTHETICAL PROTEIN
PH0099

(Pyrococcus
horikoshii)
5 / 12 HIS A  71
GLU A  98
ILE A  94
ILE A  41
ALA A 104
None
1.36A 1ki7A-1vgjA:
undetectable
1ki7A-1vgjA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)
1vgj HYPOTHETICAL PROTEIN
PH0099

(Pyrococcus
horikoshii)
4 / 5 LEU A  46
LEU A  61
ILE A 107
ALA A   6
None
0.76A 2i2zA-1vgjA:
undetectable
2i2zA-1vgjA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)
1vgj HYPOTHETICAL PROTEIN
PH0099

(Pyrococcus
horikoshii)
3 / 3 LYS A 164
LEU A 177
ALA A   3
None
0.63A 4iizA-1vgjA:
undetectable
4iizA-1vgjA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)
1vgj HYPOTHETICAL PROTEIN
PH0099

(Pyrococcus
horikoshii)
4 / 7 VAL A 157
ARG A 101
ILE A  94
ALA A 124
None
0.83A 4lv9A-1vgjA:
undetectable
4lv9A-1vgjA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)
1vgj HYPOTHETICAL PROTEIN
PH0099

(Pyrococcus
horikoshii)
4 / 7 VAL A 157
ARG A 101
ILE A  94
ALA A 124
None
0.81A 4lv9B-1vgjA:
undetectable
4lv9B-1vgjA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)
1vgj HYPOTHETICAL PROTEIN
PH0099

(Pyrococcus
horikoshii)
3 / 3 LYS A  70
ASN A  96
ASP A 158
None
0.83A 4o1eA-1vgjA:
undetectable
4o1eA-1vgjA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')
1vgj HYPOTHETICAL PROTEIN
PH0099

(Pyrococcus
horikoshii)
5 / 9 LEU A  17
VAL A  13
VAL A  75
ILE A  41
ASP A   8
None
1.17A 5yf9X-1vgjA:
undetectable
5yf9X-1vgjA:
19.77