SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vh0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		4 / 6 LEU A 125
GLU A  91
THR A  72
LEU A  76
 None
 1.27A 1etb2-1vh0A:
undetectable		 1etb2-1vh0A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		6 / 9 LEU A  76
ILE A 107
GLY A 108
GLY A 112
SER A 126
SER A 128
 None
 0.65A 2qmmA-1vh0A:
7.2		 2qmmA-1vh0A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		6 / 11 LEU A  76
ILE A 107
GLY A 108
GLY A 112
SER A 126
SER A 128
 None
 0.70A 2qmmA-1vh0A:
7.2
2qmmB-1vh0A:
7.0		 2qmmA-1vh0A:
24.17
2qmmB-1vh0A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		5 / 12 ILE A 107
GLY A  60
ALA A   7
LEU A   6
VAL A  55
 None
 1.15A 2yvlB-1vh0A:
undetectable		 2yvlB-1vh0A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		5 / 10 GLU A  37
ILE A 107
GLY A 109
LEU A 118
ILE A  63
 None
 1.09A 3adsA-1vh0A:
undetectable		 3adsA-1vh0A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		5 / 9 LEU A  76
ILE A 107
GLY A 108
SER A 126
SER A 128
 None
 0.49A 3ai9X-1vh0A:
6.9		 3ai9X-1vh0A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		5 / 12 ILE A 107
VAL A 106
GLY A 109
ALA A   7
ILE A  52
 None
 1.01A 3mb5A-1vh0A:
undetectable		 3mb5A-1vh0A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		4 / 8 ILE A  33
ILE A   3
PHE A 105
SER A  85
 None
 0.84A 4ac9C-1vh0A:
undetectable		 4ac9C-1vh0A:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		4 / 8 ILE A  33
ILE A   3
PHE A 105
SER A  85
 None
 0.80A 4acbC-1vh0A:
undetectable		 4acbC-1vh0A:
15.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		5 / 10 GLY A 109
GLY A 112
SER A 128
THR A 131
PHE A 132
 None
 0.99A 4fakA-1vh0A:
29.2		 4fakA-1vh0A:
96.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		8 / 10 LEU A  76
GLY A 108
GLY A 109
PHE A 127
SER A 128
THR A 131
PHE A 132
MET A 137
 None
 1.29A 4fakA-1vh0A:
29.2		 4fakA-1vh0A:
96.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		10 / 10 LEU A  76
ILE A  78
ILE A 107
GLY A 108
GLY A 112
PHE A 127
SER A 128
THR A 131
PHE A 132
MET A 137
 None
 0.33A 4fakA-1vh0A:
29.2		 4fakA-1vh0A:
96.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 ILE A   3
MET A 152
ARG A 153
 None
 0.92A 4lnwA-1vh0A:
undetectable		 4lnwA-1vh0A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 ILE A   3
MET A 152
ARG A 153
 None
 0.91A 4lnxA-1vh0A:
undetectable		 4lnxA-1vh0A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.60A 5qgjA-1vh0A:
undetectable		 5qgjA-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.66A 5qglA-1vh0A:
undetectable		 5qglA-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.61A 5qgmA-1vh0A:
undetectable		 5qgmA-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.62A 5qguA-1vh0A:
undetectable		 5qguA-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.69A 5qgvA-1vh0A:
undetectable		 5qgvA-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.69A 5qgwA-1vh0A:
undetectable		 5qgwA-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.69A 5qgxA-1vh0A:
undetectable		 5qgxA-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.67A 5qh0A-1vh0A:
undetectable		 5qh0A-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.73A 5qh1A-1vh0A:
undetectable		 5qh1A-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.67A 5qh4A-1vh0A:
undetectable		 5qh4A-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.67A 5qh6A-1vh0A:
undetectable		 5qh6A-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.64A 5qh9A-1vh0A:
undetectable		 5qh9A-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.64A 5qhaA-1vh0A:
undetectable		 5qhaA-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.67A 5qhcA-1vh0A:
undetectable		 5qhcA-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.66A 5qheA-1vh0A:
undetectable		 5qheA-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.65A 5qhfA-1vh0A:
undetectable		 5qhfA-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.70A 5qhgA-1vh0A:
undetectable		 5qhgA-1vh0A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		3 / 3 VAL A   8
VAL A  38
GLN A  61
 None
 0.66A 5qhhA-1vh0A:
undetectable		 5qhhA-1vh0A:
22.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		9 / 12 LEU A  76
ILE A  78
ILE A 107
GLY A 108
GLY A 112
SER A 126
SER A 128
THR A 131
HIS A 134
 None
 0.57A 5twjA-1vh0A:
23.6		 5twjA-1vh0A:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		7 / 10 LEU A  76
ILE A  78
ILE A 107
GLY A 108
GLY A 112
SER A 128
HIS A 134
 None
 0.50A 5twjB-1vh0A:
23.2		 5twjB-1vh0A:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		7 / 12 LEU A  76
ILE A  78
ILE A 107
GLY A 108
LEU A 113
SER A 126
SER A 128
 None
 0.51A 5twjC-1vh0A:
23.4		 5twjC-1vh0A:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		7 / 11 LEU A  76
ILE A  78
ILE A 107
GLY A 108
GLY A 112
SER A 128
THR A 131
 None
 0.56A 5twjD-1vh0A:
23.4		 5twjD-1vh0A:
32.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1vh0 HYPOTHETICAL UPF0247
PROTEIN
SAV0024/SA0023
(Staphylococcus
aureus) 		6 / 11 LEU A  76
ILE A 107
GLY A 108
GLY A 109
SER A 128
THR A 131
 None
 1.27A 5twjD-1vh0A:
23.4		 5twjD-1vh0A:
32.34