SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vh2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.74A 1v54A-1vh2A:
undetectable
1v54A-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.75A 1v54N-1vh2A:
undetectable
1v54N-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.74A 1v55A-1vh2A:
undetectable
1v55A-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.74A 1v55N-1vh2A:
undetectable
1v55N-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.72A 2dyrA-1vh2A:
1.4
2dyrA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.75A 2dyrN-1vh2A:
undetectable
2dyrN-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.69A 2dysA-1vh2A:
undetectable
2dysA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.68A 2dysN-1vh2A:
undetectable
2dysN-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.72A 2eijA-1vh2A:
undetectable
2eijA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.73A 2eijN-1vh2A:
undetectable
2eijN-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.70A 2eikA-1vh2A:
0.0
2eikA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.74A 2eikN-1vh2A:
0.0
2eikN-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.71A 2eilA-1vh2A:
0.0
2eilA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.72A 2eilN-1vh2A:
0.0
2eilN-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.75A 2eimA-1vh2A:
undetectable
2eimA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.70A 2eimN-1vh2A:
undetectable
2eimN-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.66A 2einA-1vh2A:
undetectable
2einA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.70A 2einN-1vh2A:
undetectable
2einN-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
4 / 6 PRO A 118
HIS A  57
ASP A  52
ASP A 132
None
ZN  A 167 (-3.4A)
None
None
1.20A 2lh8A-1vh2A:
0.0
2lh8A-1vh2A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
4 / 6 ARG A 137
THR A  58
ALA A 136
PRO A 118
None
1.36A 2ql8A-1vh2A:
2.7
2ql8B-1vh2A:
2.7
2ql8A-1vh2A:
21.26
2ql8B-1vh2A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.78A 2zxwN-1vh2A:
undetectable
2zxwN-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.75A 3abkA-1vh2A:
undetectable
3abkA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.79A 3ablN-1vh2A:
undetectable
3ablN-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.74A 3ag2N-1vh2A:
0.0
3ag2N-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.74A 3asnA-1vh2A:
undetectable
3asnA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.75A 3asoA-1vh2A:
undetectable
3asoA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.74A 3s33A-1vh2A:
undetectable
3s33A-1vh2A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.75A 3s38A-1vh2A:
undetectable
3s38A-1vh2A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.72A 3s39A-1vh2A:
undetectable
3s39A-1vh2A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.75A 3s3aA-1vh2A:
undetectable
3s3aA-1vh2A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.72A 3s3bA-1vh2A:
undetectable
3s3bA-1vh2A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.73A 3s3cA-1vh2A:
undetectable
3s3cA-1vh2A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.72A 3s3dA-1vh2A:
undetectable
3s3dA-1vh2A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.72A 3x2qA-1vh2A:
undetectable
3x2qA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
4 / 7 PHE A  43
LEU A  44
THR A 110
VAL A 143
None
1.06A 4wnvD-1vh2A:
undetectable
4wnvD-1vh2A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.74A 5b1aA-1vh2A:
undetectable
5b1aA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.76A 5b1aN-1vh2A:
undetectable
5b1aN-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.74A 5x19A-1vh2A:
undetectable
5x19A-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.74A 5x1fA-1vh2A:
undetectable
5x1fA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.76A 5z84A-1vh2A:
undetectable
5z84A-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.75A 5z84N-1vh2A:
undetectable
5z84N-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.77A 5z85A-1vh2A:
undetectable
5z85A-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.74A 5z85N-1vh2A:
undetectable
5z85N-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.78A 5z86N-1vh2A:
0.0
5z86N-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.77A 5zcoA-1vh2A:
undetectable
5zcoA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.73A 5zcoN-1vh2A:
undetectable
5zcoN-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.74A 5zcpA-1vh2A:
undetectable
5zcpA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.75A 5zcpN-1vh2A:
0.0
5zcpN-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.73A 5zcqA-1vh2A:
0.0
5zcqA-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
3 / 3 HIS A  61
HIS A 131
HIS A  57
ZN  A 167 (-3.3A)
ZN  A 167 ( 4.9A)
ZN  A 167 (-3.4A)
0.74A 5zcqN-1vh2A:
0.0
5zcqN-1vh2A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)
1vh2 S-RIBOSYLHOMOCYSTEIN
ASE

(Deinococcus
radiodurans)
4 / 4 ASP A 132
ILE A 117
PRO A 116
LEU A 133
None
1.46A 6mkeB-1vh2A:
undetectable
6mkeB-1vh2A:
18.52