SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vhf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2003_1
(SERUM ALBUMIN)		 1vhf PERIPLASMIC DIVALENT
CATION TOLERANCE
PROTEIN
(Thermotoga
maritima) 		5 / 10 LEU A  69
HIS A  73
LEU A  21
ILE A  27
ALA A  53
 None
 0.95A 2bxeB-1vhfA:
undetectable		 2bxeB-1vhfA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 1vhf PERIPLASMIC DIVALENT
CATION TOLERANCE
PROTEIN
(Thermotoga
maritima) 		5 / 12 LEU A  69
HIS A  73
LEU A  21
ILE A  27
ALA A  53
 None
 0.99A 2bxqA-1vhfA:
undetectable		 2bxqA-1vhfA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1vhf PERIPLASMIC DIVALENT
CATION TOLERANCE
PROTEIN
(Thermotoga
maritima) 		4 / 6 LEU A  21
PHE A  30
PHE A  55
LEU A  69
 None
 1.03A 3wg7C-1vhfA:
undetectable
3wg7J-1vhfA:
undetectable		 3wg7C-1vhfA:
15.71
3wg7J-1vhfA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vhf PERIPLASMIC DIVALENT
CATION TOLERANCE
PROTEIN
(Thermotoga
maritima) 		4 / 6 LEU A  21
PHE A  30
PHE A  55
LEU A  69
 None
 1.09A 5x19P-1vhfA:
undetectable		 5x19P-1vhfA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1vhf PERIPLASMIC DIVALENT
CATION TOLERANCE
PROTEIN
(Thermotoga
maritima) 		4 / 5 LEU A  21
PHE A  30
PHE A  55
LEU A  69
 None
 1.09A 5x1bP-1vhfA:
undetectable		 5x1bP-1vhfA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1vhf PERIPLASMIC DIVALENT
CATION TOLERANCE
PROTEIN
(Thermotoga
maritima) 		4 / 7 LEU A  21
PHE A  30
PHE A  55
LEU A  69
 None
 1.03A 5x1fP-1vhfA:
undetectable
5x1fW-1vhfA:
undetectable		 5x1fP-1vhfA:
15.71
5x1fW-1vhfA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1vhf PERIPLASMIC DIVALENT
CATION TOLERANCE
PROTEIN
(Thermotoga
maritima) 		4 / 8 ILE A  17
PHE A   8
ARG A  70
LEU A  65
 None
 0.95A 5zcqN-1vhfA:
undetectable
5zcqW-1vhfA:
undetectable		 5zcqN-1vhfA:
11.13
5zcqW-1vhfA:
17.31