SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vhi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 1vhi EPSTEIN BARR VIRUS
NUCLEAR ANTIGEN-1
(Human
gammaherpesvirus
4) 		5 / 9 LEU A 485
PHE A 562
LEU A 533
VAL A 507
LEU A 575
 None
 1.17A 1e7aB-1vhiA:
undetectable		 1e7aB-1vhiA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1vhi EPSTEIN BARR VIRUS
NUCLEAR ANTIGEN-1
(Human
gammaherpesvirus
4) 		4 / 7 THR A 524
LEU A 485
VAL A 595
ILE A 593
 None
 0.79A 1t87B-1vhiA:
undetectable		 1t87B-1vhiA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 1vhi EPSTEIN BARR VIRUS
NUCLEAR ANTIGEN-1
(Human
gammaherpesvirus
4) 		4 / 4 LEU A 575
ARG A 521
LEU A 520
ALA A 525
 None
 1.14A 3b9mA-1vhiA:
undetectable		 3b9mA-1vhiA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 1vhi EPSTEIN BARR VIRUS
NUCLEAR ANTIGEN-1
(Human
gammaherpesvirus
4) 		5 / 10 THR A 524
PHE A 571
GLN A 530
ARG A 496
LEU A 485
 None
 1.16A 3kvrA-1vhiA:
undetectable		 3kvrA-1vhiA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 1vhi EPSTEIN BARR VIRUS
NUCLEAR ANTIGEN-1
(Human
gammaherpesvirus
4) 		5 / 10 THR A 524
PHE A 571
GLN A 530
ARG A 496
LEU A 485
 None
 1.15A 3kvrB-1vhiA:
undetectable		 3kvrB-1vhiA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 1vhi EPSTEIN BARR VIRUS
NUCLEAR ANTIGEN-1
(Human
gammaherpesvirus
4) 		4 / 8 ASN A 475
PRO A 476
MET A 469
PHE A 478
 None
 1.45A 4v30B-1vhiA:
0.0		 4v30B-1vhiA:
22.09