SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1vhm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 1vhm PROTEIN YEBR
(Escherichia
coli) 		4 / 8 TYR A  25
PHE A  24
THR A  49
LEU A  53
 None
 1.30A 1ea1A-1vhmA:
undetectable		 1ea1A-1vhmA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 1vhm PROTEIN YEBR
(Escherichia
coli) 		4 / 8 THR A  49
LEU A 165
VAL A 168
THR A 172
 None
 1.05A 1uyuB-1vhmA:
undetectable		 1uyuB-1vhmA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1vhm PROTEIN YEBR
(Escherichia
coli) 		4 / 7 THR A  49
LEU A 165
VAL A 168
THR A 172
 None
 1.03A 3fwiA-1vhmA:
undetectable		 3fwiA-1vhmA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1vhm PROTEIN YEBR
(Escherichia
coli) 		4 / 4 PRO A 129
LEU A 128
ILE A 126
ARG A 105
 None
 1.22A 3w1wA-1vhmA:
undetectable		 3w1wA-1vhmA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_1
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 1vhm PROTEIN YEBR
(Escherichia
coli) 		3 / 3 GLU A 125
ASP A 143
ASP A 108
 MES  A 194 (-3.2A)
MES  A 194 (-4.0A)
None
 0.67A 4gc9A-1vhmA:
undetectable		 4gc9A-1vhmA:
21.61